The fractions obtained from ethanolic extract from Sesbania virgata leaves showed cytotoxic activities on Vero and MDBK cells and promising antiviral activities against bovine and swine herpesvirus.
KEY WORDS:
Sesbania virgata; antiherpes activity; bovine herpesvirus; swine herpesvirus; cytotoxicity.
| Tested materials | MDBK cells | Vero cells | ||||
|---|---|---|---|---|---|---|
| NTMC (μg/mL) | Antiviral activity (SI) | NTMC (μg/mL) | Antiviral activity (SI) | |||
| BHV-1 | SHV-1 | BHV-1 | SHV-1 | |||
| EE | 125 | 4,0 | 1,0 | 125 | 1,0 | 1,0 |
| WIF | 125 | 4,0 | 1,0 | 125 | 1,0 | 1,0 |
| EAF | 125 | 8,0 | 1,0 | 62,50 | 1,0 | 1,0 |
| BF | 250 | 2,0 | 1,0 | 62,50 | 1,0 | 1,0 |
| F-l | 3,91 | 32,58 | 1,0 | 15,62 | 2,0 | 2,0 |
| F-2 | 3,91 | 16,29 | 1,0 | 15,62 | 2,0 | 2,0 |
| F-3 | 15,62 | 3,99 | 1,0 | 31,25 | 1,0 | 1,0 |
| F-4 | 15,62 | 3,99 | 1,0 | 31,25 | 1,0 | 1,0 |
| F-5 | 15,62 | 3,99 | 1,0 | 31,25 | 1,0 | 1,0 |
