ABSTRACT
In order to evaluate the effect of the octuple vaccine (Duramune DA2PP+ CvK/LCI - Fort Dodge) on the leukogram and neutrophil oxidative metabolism, analyses were made of blood of 20 adult healthy dogs at 4 different moments: M0 (before the vaccination), M1 (2 days after), M2 (15 days after) andM 3 (30 days after). The neutrophil oxidative metabolism estimated by nitroblue tetrazolium (NBT) reduction test didn’t show any significative differences among the moments studied, on neither the stimulated test nor on the non-stimulated one. The results show that the polyvalent vaccine does not interfere on the neutrophil oxidative metabolism, nor on the leukogram.
KEY WORDS:
Vaccine response; nbt; octuple vaccine; immunosupression.