Therapeutic results with Mogadon in 68 children with epilepsy (34 cases of West syndrome, 14 with tipical P.M. seizures, 20 with atypical P.M. seizures) resistant to conventional therapy employed previously in various combinations for prolonged periods, is reported. The majority of the patients showed intense psychomotor retardation, probably due to the non-controlled evolution of the cases, before the administration of Mogadon. Results were excellent in regard to the control of the crise's frequency (100% in 28, 75% in 22, 50% in 10, 25% in one, and null in 7 cases). Concerning the psychomotor development the results were less evident. Side effects were negligible, being absent in 41 cases; 23 patients showed somnolence, accompanied by ataxia in two cases. Four patients complained of insomnia, promptly controlled with barbiturates. The period of post-treatment follow-up ranged between 6 and 18 months.