A 33-year-old woman presented with breathing discomfort, cough, and fever. The real-time reverse-transcriptase polymerase-chain-reaction (rRT-PCR) analysis was positive for coronavirus disease 2019 (COVID-19). The computed tomography (CT) scan showed ground glass opacities in lung parenchyma (►Figure 1A-C). The patient was treated with favipiravir. One month after discharge, the magnetic resonance imaging (MRI) scan showed a lesion in the corpus callosum (►Figure 2A–B). The imaging results were compatible with a transient splenial lesion. The patient was completely recovered after 1 month, without any specific treatment. Control MRI showed complete resolution of the lesion (►Figure 2C-D). We thought that the splenial lesion was caused by the coronavirus infection; COVID-19 infection presenting with transient splenial lesion in an adult patient has been reported in only a few cases.11 Hayashi M, Sahashi Y, Baba Y, Okura H, Shimohata T. COVID-19-associated mild encephalitis/encephalopathy with a reversible splenial lesion. J Neurol Sci 2020;415:116941, 22 El Aoud S, Sorial D, Selmaoui A, et al. A first case of Mild Encephalitis with Reversible Splenial Lesion(MERS) as a presenting feature of SARS-CoV-2. Rev Neurol (Paris) 2021;177(1-2):139–141, 33 Chauffier J, Poey N, Husain M, et al. First Case of Mild Encephalopathy with Reversible Splenial Lesion in SARS-CoV-2 Infection. Infect Dis Now 2021;51(01):99–101
(A–C) Axial thorax CT during the presentation scans show ground glass opacities (circles) in both lung parenchyma.
References
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1Hayashi M, Sahashi Y, Baba Y, Okura H, Shimohata T. COVID-19-associated mild encephalitis/encephalopathy with a reversible splenial lesion. J Neurol Sci 2020;415:116941
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2El Aoud S, Sorial D, Selmaoui A, et al. A first case of Mild Encephalitis with Reversible Splenial Lesion(MERS) as a presenting feature of SARS-CoV-2. Rev Neurol (Paris) 2021;177(1-2):139–141
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3Chauffier J, Poey N, Husain M, et al. First Case of Mild Encephalopathy with Reversible Splenial Lesion in SARS-CoV-2 Infection. Infect Dis Now 2021;51(01):99–101
Publication Dates
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Publication in this collection
23 Jan 2023 -
Date of issue
2022
History
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Received
11 Nov 2021 -
Accepted
19 Feb 2022