In 10 patients with functional uterine bleeding, the existence of epileptic manifestations (clinical and electroencephalographic) was investigated: 7 among the 10 cases had a previous history and/or symptoms of a nature that was probably Or certainly epileptic; the electroencephalogram showed abnormalities in 5 cases. The action of intravenous Premarin (20 mg) was studied during electroencephalogram recording. There was no change in the normal electroencephalogram and in the patological ones there was not an increase of the abnormalities.