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Status epilepticus in Lennox-Gastaut syndrome: therapeutic aspects

Therapeutic aspects of convulsive and non convulsive status epilepticus observed in fourteen patients with Lennox-Gastaut syndrome were studied. A temporal relationship between the status epilepticus onset and the beginning of treatment with chlonazepam and diphenylhydantoin was observed; these drugs withdrawal was followed by suppression of symptoms. The possibility of treating status epilepticus by altering the orally administered therapy and leaving parenteral therapy for such cases with progressive impairment of consciousness and/or neuvoregetative disorders was indicated.


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