Del Ser et al.3131. Del Ser T, Hachinski V, Merskey H, Munoz DG. Clinical and pathologic features of two groups of patients with dementia with Lewy bodies: effect of coexisting Alzheimer-type lesion load. Alzheimer Dis Assoc Disord. Jan-Mar 2001;15(1):31-44. https://doi.org/10.1097/00002093-200101000-00005 https://doi.org/https://doi.org/10.1097/...
|
Not specified |
Retrospective cohort |
Pathological evaluation of patients from an outpatient setting |
11 pure DLB, 35 pure AD, 18 AD+DLB (pathological signs of both diseases) |
Neuropathological examination + DLB consensus criteria (McKeith, 1996) |
Not specified; patients were evaluated as either having loss of insight or not |
|
p = 0.03 |
8/9 |
Hanyu et al.3535. Hanyu H, Sato T, Akai T, Sakai M, Takasaki R, Iwamoto T. [Awareness of memory deficits in patients with dementias: a study with the Everyday Memory Checklist. Nihon Ronen Igakkai Zasshi. 2007 Jul;44(4):463-9. https://doi.org/10.3143/geriatrics.44.463 https://doi.org/https://doi.org/10.3143/...
|
Memory |
Cross-sectional |
Outpatient clinic |
17 DLB, 63 AD, 56 MCI, 14 VaD |
DLB consensus criteria (McKeith 2005) |
Difference between the Everyday Memory Checklist (EMC) filled by the patient and a caregiver. Patients with anosognosia were defined as having a difference greater than 9 |
|
p < 0.0001 |
7/9 |
Iizuka et al.3232. Iizuka T, Kameyama M. Metabolic correlate of memory-deficit awareness in dementia with Lewy bodies: Implication in cortical midline structure. Psychiatry Res Neuroimaging. 2017 Nov;269:43-7. https://doi.org/10.1016/j.pscychresns.2017.09.007 https://doi.org/https://doi.org/10.1016/...
|
Memory |
Cross-sectional |
Hospital-based study |
34 DLB, 18 HC |
DLB consensus criteria (McKeith 2005) |
Index comparing objective memory loss (RAVLT) and subjective memory loss (MAC-Q) |
|
p < 0.01 |
6/9 |
Rahman-Filipiak et al.3636. Rahman-Filipiak AM, Giordani B, Heidebrink J, Bhaumik A, Hampstead BM. Self-and informant-reported memory complaints: frequency and severity in cognitively intact individuals and those with mild cognitive impairment and neurodegenerative dementias. J Alzheimers Dis. 2018;65(3):1011-27. https://doi.org/10.3233/JAD-180083 https://doi.org/https://doi.org/10.3233/...
|
Memory |
Cross-sectional |
Participants recruited from the community |
16 DLB, 186 HC, 24 naMCI, 46 aMCI-SD, 71 aMCI-MD, 129 AD, 16 FTD |
DLB consensus criteria (McKeith 2005) |
The study did not calculate a specific anosognosia index but compared the scores of the traditional version of MAC-Q (subjective memory loss) and an informant version (MAC-F) across different diagnoses. |
|
-
p < 0.004 for HC
-
p = 0.999 for AD
|
7/9 |
Ballard et al.3333. Ballard C, McKeith I, Harrison R, O'Brien J, Thompson P, Lowery K, et al. A detailed phenomenological comparison of complex visual hallucinations in dementia with Lewy bodies and Alzheimer's disease. Int Psychogeriatr. 1997 Dec;9(4):381-8. https://doi.org/10.1017/s1041610297004523 https://doi.org/https://doi.org/10.1017/...
|
Visual hallucinations |
Cross-sectional |
Outpatient clinic |
38 DLB, 8 AD* |
Operational criteria for senile dementia of Lewy body type (McKeith 1992) |
Standardized interview. Insight was classified as absent or partial |
|
|
5/9 |
Reckner et al.3434. Reckner E, Cipolotti L, Foley JA. Presence phenomena in parkinsonian disorders: phenomenology and neuropsychological correlates. Int J Geriatr Psychiatry. 2020 Jul;35(7):785-93. https://doi.org/10.1002/gps.5303 https://doi.org/https://doi.org/10.1002/...
|
Presence phenomena |
Cross-sectional |
Outpatient clinic |
|
DLB consensus criteria (McKeith, 2017) |
Semi-structured interview. Insight was classified as reduced or preserved |
|
Not described; study did not focus on comparison between etiologies |
6/9 |