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Clinical and metabolic alterations and insulin resistance among adolescents

Abstract

Objective

Analyzing the clinical and metabolic alterations and their relation to insulin resistance among adolescents.

Methods

Analytic study, carried out with 357 adolescents of state public schools in a municipality in Northeastern Brazil. The applied form contained the variables Body Mass index, Waist Circumference, Neck Circumference, Taper index, Average Blood Pressure, Triglycerides, Blood Sugar Level, High-Density Lipoprotein Cholesterol, insulin, and Homeostasis Model Assessment Index, analyzed through descriptive measures for quantitative variables; and through frequency for qualitative variables. Association tests were made through Chi-Square test and through Odds Ratio.

Results

Prevalence of insulin resistance was 33.9%. The average values of waist circumference, neck circumference, taper index, average systolic blood pressure and average diastolic blood pressure were high in, respectively, 4.2%, 30%, 10.9%, 4.2% and 14% of adolescents. High-Density Lipoprotein Cholesterol levels were decreased in 30.5% of the sample, whereas triglycerides were high in 18.8%. No blood sugar alteration was identified. Those who presented altered values for body mass index, waist circumference, neck circumference, taper index, and triglycerides had higher chances to present insulin resistance (OD: 3.62, 11.54, 3.50, 4.49, 3.05, respectively). On the other hand, adolescents with altered average systolic blood pressure, average diastolic blood pressure and High-Density Lipoprotein Cholesterol did not present statistical significance (p<0.05).

Conclusion

Insulin resistance is present among adolescents, with positive and significant association to clinical and metabolic alterations.

Keywords
Insulin resistance; Adolescent; Obesity; Risk factors; Chronic diseases

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