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Prevalence of clinical complications high risk associated with AIDS death

Abstract

Objective:

To investigate the high risk prevalence among deaths from the risk classification of clinical complications associated with AIDS and its relation with sociodemographic and therapeutic variables.

Methods:

A retrospective epidemiological study involving 80 cases of death from AIDS between 2007 and 2015 in a Northeastern Brazilian state. Risk stratification considered follow-up indicators obtained in the infection diagnosis, assigning values of 1,2 for viral load, and 1,2 and 3 for CD4 + T lymphocytes indicators, number of opportunistic diseases, clinical manifestations and chronic diseases. ranging from 5 to 14. The higher this score, the greater the risk for clinical complications. Data were analyzed by estimating prevalence and prevalence ratio for high risk, followed by Weight of Evidence method and Somers' D statistic.

Results:

Of the 80 cases studied, 51.2% were allocated to the high-risk stratum. The record of psychiatric history increased by 2 times the prevalence for high risk and age group was strongly related to this stratum. T-CD4 + lymphocyte count, opportunistic diseases and clinical manifestations were the indicators that showed the strongest association strength with risk stratification.

Conclusion:

The study showed the prevalence of high risk for the development of clinical complications, greater associative strength in LT-CD4 + indicators, opportunistic diseases and clinical manifestations with proposed risk score. These results suggest the need for special attention from specialized care services to outpatients.

Keywords
Prevalence; Acquired immunodeficiency syndrome; Mortality registries; Risk; Risk assessment

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