Palacín et al. (2008)Palacín I, Abecia JA, Forcada F, Casao A, Cebrián JÁ, Muiño T, Pontes JM. Effects of exogenous melatonin treatment on out-of-season ram fertility. Ital J Anim Sci. 2008;7(2):199-206. http://doi.org/10.4081/ijas.2008.199. http://doi.org/10.4081/ijas.2008.199...
|
Outside |
8 Soay |
Subcutaneous implant |
Seminal vesicles were removed |
88 days |
Silastic sheet (500-1DOw Corning sheeting, Midland, MI, USA) 1 g |
After melatonin administration, emphasis was on the secretory epithelium characteristics. Induced a significant increase in the number and height of principal cells that showed signs of increased secretory activity. Main cytological alterations in the principal cells: increase in the concentrically arranged membranes of secretory vacuoles and glycogen granules, appearance of numerous lysosomes and multivesicular bodies |
Casao et al. (2010a) |
Outside |
2 Aragonesa |
Subcutaneous implant |
Artificial vagina |
66 to day 126 |
3, 18-mg melatonin implants (Melovine; Ceva Sanidad Animal, Barcelona, Spain) |
Increased the percentage of progressive motile spermatozoa |
Outside |
16 Dohne Merino |
Subcutaneous implant |
Artificial vagina |
30 to day 78 |
3, 18-mg melatonin implants (Melovine; Ceva Sanidad Animal, Barcelona, Spain) |
Increase in the scrotal circumference without changing the seminal quality parameters of fresh and frozen/thawed semen |
Rekik et al. (2015)Rekik M, Taboubi R, Ben Salem I, Fehri Y, Sakly C, Lassoued N, Hilali ME. Melatonin administration enhances the reproductive capacity of young rams under a southern Mediterranean environment. Anim Sci J. 2015;86(7):666-72. http://doi.org/10.1111/asj.12350. PMid:25689168. http://doi.org/10.1111/asj.12350...
|
Outside |
7 Barbarine 10 Saint Croix rams |
Subcutaneous implant |
Artificial vagina |
24 days |
3, 18-mg melatonin implants (Melovine; Ceva Sanidad Animal, Barcelona, Spain) |
Increased sperm concentration at the end of the experimental period. Scrotal circumference increased, and mating behaviour improved |
Abecia et al. (2018)Abecia JA, Araya J, Chemineau P, Palacios C, Keller M, Delgadillo JA. Photoperiod-melatonin-induced, sexually-activated rams increase pregnancy rate and number of lambs per ewe in a ram effect. Large Anim Rev. 2018;24:31-5.
|
Outside |
6 Aragonesa |
Subcutaneous implant |
Blood |
0-30 days |
3, 18-mg melatonin implants (Melovine; Ceva Sanidad Animal, Barcelona, Spain) |
Treated rams exhibited certain sexual behaviours and had higher plasma testosterone concentrations |
More of the ewes that mated with those rams became pregnant and produced more lambs per ewe compared to those that mated with non-treated rams |
Pool et al. (2020a)Pool KR, Rickard JP, De Graaf SP. Exogenous melatonin advances the ram breeding season and increases testicular function. Sci Rep. 2020a;10(1):1-11. http://doi.org/10.1038/s41598-020-66594-6. PMid:32546776. http://doi.org/10.1038/s41598-020-66594-...
|
Outside |
31, Merino and Poll Dorset |
Subcutaneous implant |
Blood |
0 to day 72 |
Unmentioned |
Increased blood plasma testosterone levels. Growth in testicular size and sperm count per ejaculation between weeks 3 and 12 after implantation. Reduced sperm DNA fragmentation in Poll Dorset rams during multiple weeks of the non-reproductive season |
Abd-Elhafeez et al. (2021)Abd-Elhafeez HH, Hassan AHS, Hussein MT. Melatonin administration provokes the activity of dendritic reticular cells in the seminal vesicle of Soay ram during the non-breeding season. Sci Rep. 2021;11(1):872. http://doi.org/10.1038/s41598-020-79529-y. PMid:33441634. http://doi.org/10.1038/s41598-020-79529-...
|
Outside |
8 Soay |
Sub- cutaneous implant |
Seminal vesicles were removed |
66 days |
Silastic sheet (500-1DOw Corning sheeting, Midland, MI, USA) 1 g |
Melatonin administration stimulated dendritic cells and macrophages through increasing the size and number of the endosomal compartments, which may correlate to increased immunity |
Assani et al. (2023)Assani BVM, Ayssiwede SB, Kinnou MS. Evaluation of the effects of melatonin implants on testicular and spermatic parameters of rams raised in station in the niayes zone in senegal. Anim Vet Sci. 2023;11(3):55-63. http://doi.org/10.11648/j.avs.20231103.11. http://doi.org/10.11648/j.avs.20231103.1...
|
Outside |
6 Touabire x Ladoum and Touabire x Peul Peul |
Sub- cutaneous implant |
Electroejaculator |
60 to day 135 |
3, 18-mg melatonin implants (Melovine; Ceva Sanidad Animal, Barcelona, Spain) |
Induced improvements in ejaculate volume, colour and appearance, sperm production and morphological abnormality rate; sperm motility and survival rate of spermatozoa were significantly improved |