Vieira1111 Vieira RAdC, Lopes A, Oliveira HV, et al. Anal paracoccidioidomycosis: an unusual presentation of disseminated disease. Rev Soc Bras Med Trop. 2001;34 (6):583-6., 2001 |
Brazil |
60 |
M |
Weight loss, coughing, dyspnea, dysphonia, ulcerated anal lesion, sphincteral hyponony |
Large intestine, rectum |
No |
No |
SFD |
Recovery |
High |
Muñoz Urribarri1212 Muñoz Urribarri AB, Chaparro Dammert E, Ferrufino Llach JC, Vasquez Flores L. Apendicitis por Paracoccidioides brasiliensis. Rev Med Herediana. 2006;17(1):58-60., 2006 |
Peru |
5 |
M |
Vomiting, abdominal pain, fever |
Large intestine |
No |
No |
ICZ, SI |
Recovery |
High |
Duani1313 Duani H, Nunes VRT, Assumpç ão AB, et al. Bilateral paracoccidioidomycotic iliopsoas abscess associated with ileo-colonic lesion. Rev Soc Bras Med Trop. 2012;45(5):649-51., 2012 |
Brazil |
24 |
M |
Fatigue, weight loss, diarrhea, hematochezia, abdominal pain, fever |
Large intestine |
No |
Yes |
SMZ-TMP, AmB, ICZ, SFD |
Recovery |
High |
Penna1414 Penna F. Blastomycosis of the colon resembling clinically ulcerative colitis. Gut. 1979;20(10):896-9., 1979 |
Brazil |
8 |
F |
Anorexia, diarrhea, hematochezia, abdominal pain, fever |
Large intestine, rectum |
No |
Yes |
SMZ-TMP |
Recovery |
High |
Bravo1515 Bravo EA, Zegarra AJ, Piscoya A, et al. Chronic diarrhea and pancolitis caused by paracoccidioidomycosis: a case report. Case Rep Med. 2010;2010., 2010 |
Peru |
39 |
F |
Weight loss, diarrhea, hematochezia, abdominal pain, fever |
Large intestine |
No |
No |
AmB |
Death |
Moderate |
Benard1616 Benard G, Costa A, Leopércio A, Vicentini A, Kono A, Shikanai-Yasuda M. Chronic paracoccidioidomycosis of the intestine as single organ involvement points to an alternative pathogenesis of the mycosis. Mycopathologia. 2013;176 (5):353-7., 2013 |
Brazil |
58 |
F |
Weight loss, diarrhea, fever |
Large intestine |
No |
No |
ICZ |
Recovery |
High |
Benard1616 Benard G, Costa A, Leopércio A, Vicentini A, Kono A, Shikanai-Yasuda M. Chronic paracoccidioidomycosis of the intestine as single organ involvement points to an alternative pathogenesis of the mycosis. Mycopathologia. 2013;176 (5):353-7., 2013 |
Brazil |
56 |
F |
Two colonic polyps found on routine colonoscopy |
Large intestine |
No |
No |
ICZ, endoscopic removal of the polyps |
Recovery |
Moderate |
Alcántara1717 Alcántara FC, Verástegui R, Aphang LM, Cáceres AD. Colon Paracoccidioidomycosis in a hospital from Lima-Peru: report of 4 cases. Rev Gastroenterol Peru. 2017;37(1):77., 2017 |
Peru |
29 |
F |
Weight loss, diarrhea, hematochezia, abdominal pain, fever, dizziness |
Large intestine, rectum |
No |
No |
AmB, ICZ |
Recovery |
Moderate |
Alcántara1717 Alcántara FC, Verástegui R, Aphang LM, Cáceres AD. Colon Paracoccidioidomycosis in a hospital from Lima-Peru: report of 4 cases. Rev Gastroenterol Peru. 2017;37(1):77., 2017 |
Peru |
24 |
M |
Fatigue, weight loss, diarrhea, dizziness, dyspnea |
Small and large intestine |
No |
No |
AmB, ICZ |
Recovery |
Moderate |
Alcántara1717 Alcántara FC, Verástegui R, Aphang LM, Cáceres AD. Colon Paracoccidioidomycosis in a hospital from Lima-Peru: report of 4 cases. Rev Gastroenterol Peru. 2017;37(1):77., 2017 |
Peru |
29 |
M |
Weight loss, diarrhea, abdominal pain, severe anemia |
Large intestine |
No |
No |
ICZ, SMZ-TMP |
Recovery |
Moderate |
Martinez1818 Martinez CAR, Priolli DG, Ramos CO, Waisberg J, Margarido NF. Paracoccidioidomicose do cólon: relato de caso. Arq Méd ABC. 2006: 78-82., 2006 |
Brazil |
22 |
M |
Weight loss, diarrhea, abdominal pain, fever |
Small and large intestine |
No |
Yes |
ICZ |
Recovery |
Moderate |
Verona1919 Verona R, Gamarra J, Nava E, Chávez M, Perez J, Valdivia M. Colonic paracoccidioimycosis: a report on one case. Rev Gastroenterol Peru. 1998;18(3):285-91., 1998 |
Peru |
36 |
M |
Weight loss, abdominal pain, anal fissure, abdominal mass |
Small and large intestine |
No |
No |
ICZ |
Recovery |
Moderate |
Bravo2020 Bravo EA, Zegarra AJ, Piscoya A, et al. Dimorphic fungal coinfection as a cause of chronic diarrhea and pancolitis. Case Rep Med. 2011;2011., 2011 |
Peru |
34 |
M |
Upper palate, nose, mouth and right foot ulcers, weight loss, diarrhea, hematochezia |
Large intestine |
No |
No |
AmB, ICZ |
Recovery |
Moderate |
Hahn2121 Hahn RC, Morato Conceicao YT, Santos NL, Ferreira JF, Hamdan JS. Disseminated paracoccidioidomycosis: correlation between clinical and in vitro resistance to ketoconazole and trimethoprim sulphamethoxazole. Mycoses. 2003;46(8):324-9., 2003 |
Brazil |
22 |
M |
Weight loss, vomiting, abdominal pain, hepatomegaly, intestinal obstruction |
Small intestine |
No |
No |
SMZ-TMP, KCZ, AmB, FCZ, ICZ, SI |
Recovery |
High |
Meyer2222 Meyer T. Obstrucao duodenal por blastomicose sulamericana. AMB rev Assoc Med Bras. 1982:73-4., 1982 |
Brazil |
9 |
F |
Diarrhea, vomiting, abdominal pain, abdominal mass |
Small and large intestine |
No |
No |
SFD, SMZ-TMP, SI |
Recovery |
Low |
Healy2323 Healey S, Said W, Fayyaz F, Bell A. First report of paracoccidioidomycosis reactivation as a complication of immunosuppressive therapy for acute severe colitis in a caving enthusiast. BMJ Case Reports CP. 2020;13(7):e234125., 2020 |
England |
52 |
M |
Diarrhea, hematochezia, fever |
Large intestine |
UC |
No |
ICZ, SI, Posaconazol, Voriconazole, Azathioprine |
Recovery |
Low |
Galeazzi2424 Galeazzi CJ, Estofolete CF, Moraes Filho ACSd, Simoni AL, Gonç alves-Filho FdA, Netinho JG. Fungal Colitis by Paracoccidioides brasiliensis: a case report. J Coloproctol. 2011;31(4):393-6., 2011 |
Brazil |
68 |
F |
Weight loss, diarrhea, abdominal mass |
Small and large intestine |
No |
Yes |
ICZ, SFD, AmB |
NR |
Moderate |
Vinagre2525 Barrosi UMVJSMCEMd. Paracoccidioidomicose intestinal. Gastroenterol Endoscopia Dig. 2004;23:241-2., 2004 |
Brazil |
22 |
M |
Weight loss, diarrhea, hematochezia, abdominal pain, fever |
Large intestine |
No |
No |
NR |
NR |
High |
Freitas Junior2626 Freitas Junior Rd, Arcencio JL, Costa LA. Abdomen agudo inflamatorio por blastomicose sul-anericana. Relato de caso. Rev Col Bras Cir. 1991: 93-6., 1991 |
Brazil |
36 |
M |
Anorexia, vomiting, abdominal pain, fever |
Small intestine |
No |
No |
SI |
Recovery |
Moderate |
Gava2727 Gava P, de Melo ASA, Marchiori E, de Magalhães Costa MH, Pereira E, Rangel RDB. Intestinal and appendiceal paracoccidioidomycosis. Radiol Bras. 2015;48 (2):126., 2015 |
Brazil |
20 |
M |
Weight loss, hematochezia |
Mouth, small and large intestine, rectum |
No |
Yes |
AmB |
Recovery |
High |
Ribas2828 Ribas AM, Oliveira Rd, Cavalli BC, et al. Acometimento intestinal da paracoccidioidomicose: relato de caso. GED Gastroenterol Endosc Dig. 2008: 111-4., 2008 |
Brazil |
27 |
M |
Weight loss, diarrhea, hematochezia, vomiting, abdominal pain |
Large intestine |
No |
No |
SMZ-TMP, FCZ |
Recovery |
Moderate |
Rocha2929 Rocha N, Suguiama E, Maia D, Costa H, Coelho K, Franco M. Intestinal malakoplakia associated with paracoccidiodomycosis: a new association. Histopathology. 1997;30(1):79-83., 1997 |
Brazil |
26 |
M |
Diarrhea, abdominal pain, ascites |
Small and large intestine, rectum |
No |
No |
KCZ, SI, Sulfisoxazole |
Recovery |
High |
Rocha2929 Rocha N, Suguiama E, Maia D, Costa H, Coelho K, Franco M. Intestinal malakoplakia associated with paracoccidiodomycosis: a new association. Histopathology. 1997;30(1):79-83., 1997 |
Brazil |
30 |
M |
Anorexia, weight loss, diarrhea, abdominal pain |
Large intestine |
No |
No |
Antifungal therapy |
Death |
Moderate |
Lomazi8, 2018 |
Brazil |
13 |
M |
Weight loss, diarrhea, hematochezia, abdominal pain |
Large intestine, rectum |
No |
Yes |
ICZ, AmB |
Recovery |
Moderate |
Chojniak3030 Chojniak R, Vieira RAdC, Lopes A, Silva JCA, Godoy CE. Intestinal paracoccidioidomycosis simulating colon cancer. Rev Soc Bras Med Trop. 2000;33(3):309-12., 2000 |
Brazil |
57 |
NR |
Weight loss, diarrhea, abdominal pain |
Small and large intestine |
No |
No |
KCZ, SI |
Recovery |
Moderate |
Hossne3131 Hossne RS, Hossne WS, Prado RG, Bakonyi Neto A. Paracoccidioidomicose intestinal: relato de caso. GED Gastroenterol Endosc Dig. 2005:148-50., 2005 |
Brazil |
48 |
M |
Weight loss, abdominal pain |
Small and large intestine |
No |
Yes |
SI |
Recovery |
Moderate |
Gorodner3232 Gorodner OZd, Vadillo C, Otaño R, Robles A, Zittercoff J, Gonzalez H. Paracoccidioidomicosis: presentación intestinal seudotumoral. Bol Inst Med Reg. 2004:168-70., 2004 |
Argentina |
59 |
M |
Weight loss, abdominal pain |
Mouth, small intestine |
No |
No |
SI |
NR |
Moderate |
Rüssel3333 Ru€ssel M, Melo VL, Paniagua BA, Tracogna F, Giménez MF. Paracoccidioidomicosis: presentación inusual. Arch Argent Dermatol. 2016;66(1):12-4., 2016 |
Argentina |
63 |
M |
Intestinal infarction, ischemia of the right lower limb |
Small and large intestine |
No |
No |
ICZ, SI |
Death |
Moderate |
Golçalves3434 Golç alves AJR, Terra GMF, Rozenbaum R, Londero AT. Paracoccidioidomicose com enterocolite em crianç a com 12 anos. J Bras Med. 1996;50. 2, 4-, 2, 4., 1996 |
Brazil |
12 |
F |
Weight loss, diarrhea, hematochezia, vomiting, abdominal pain, fever, hepatomegaly, splenomegaly |
Small and large intestine, rectum |
No |
No |
SMZ-TMP, AmB |
Recovery |
High |
Cury3535 Cury MdS, Ribeiro BdS, Costa PP, de Lima VM, Mizsputen SJ, Ferrari AP. Paracoccidioidomycosis masquerading as Crohn’s disease. Gastrointest Endosc. 2000;51(6):722-3., 2000 |
Brazil |
43 |
M |
Weight loss, vomiting, abdominal pain |
Small and large intestine |
No |
Yes |
SMZ-TMP |
Recovery |
Moderate |
Rodríguez3636 Rodríguez JY, Rodríguez GJ, A, lvarez-Moreno CA, Ramirez VG. Paracoccidioidomycosis simulating Crohn’s disease. Int J Infect Dis. 2018;72:20-1., 2018 |
Colombia |
26 |
M |
Weight loss, diarrhea, abdominal pain |
Small and large intestine |
No |
Yes |
SMZ-TMP, AmB, SI |
Recovery |
Moderate |
Troncon3737 Troncon L, Martinez R, Meneghelli U, De Oliveira R, Iazigi N. Protein-losing enteropathy in paracoccidioidomycosis. Rev Hosp Clin. 1981;36(4):172-8., 1981 |
Brazil |
23 |
M |
Vomiting, abdominal pain, fever, hepatomegaly, jaundice; ascites |
NR |
No |
No |
AmB, SFD |
Recovery |
High |
Troncon3737 Troncon L, Martinez R, Meneghelli U, De Oliveira R, Iazigi N. Protein-losing enteropathy in paracoccidioidomycosis. Rev Hosp Clin. 1981;36(4):172-8., 1981 |
Brazil |
26 |
M |
Diarrhea, hepatomegaly, jaundice; ascites |
NR |
No |
No |
SFD |
NR |
High |
Berni3838 de Mendonça Berni AD, Júnior EE, Arão Filho A, Paniago AMM. Protein-losing enteropathy in paracoccidioidomycosis identified by scintigraphy: report of three cases. Braz J Infect Dis. 2010;14(5):540-3., 2010 |
Brazil |
53 |
M |
Weight loss, diarrhea, abdominal pain, fever, hepatomegaly |
Mouth, large intestine |
No |
No |
SMZ-TMP, AmB; ICZ; Pyrazinamide |
Recovery |
High |
Berni3838 de Mendonça Berni AD, Júnior EE, Arão Filho A, Paniago AMM. Protein-losing enteropathy in paracoccidioidomycosis identified by scintigraphy: report of three cases. Braz J Infect Dis. 2010;14(5):540-3., 2010 |
Brazil |
36 |
F |
Weight loss, abdominal pain, fever, hepatomegaly, jaundice; ascites |
Mouth, large intestine |
No |
No |
SMZ-TMP, AmB |
Recovery |
Moderate |
Berni3838 de Mendonça Berni AD, Júnior EE, Arão Filho A, Paniago AMM. Protein-losing enteropathy in paracoccidioidomycosis identified by scintigraphy: report of three cases. Braz J Infect Dis. 2010;14(5):540-3., 2010 |
Brazil |
50 |
M |
Weight loss, abdominal pain, fever, hepatomegaly, jaundice, oral lesions |
Mouth, small intestine |
No |
No |
SMZ-TMP, AmB |
Recovery |
High |
Avritchir3939 Avritchir Y, Perroni AA. Radiological manifestations of small intestinal South American blastomycosis. Radiology. 1978;127 (3):607-9., 1978 |
Brazil |
23 |
NR |
Diarrhea, palpable abdominal mass |
Small intestine |
No |
No |
AmB |
Recovery |
Moderate |
Avritchir3939 Avritchir Y, Perroni AA. Radiological manifestations of small intestinal South American blastomycosis. Radiology. 1978;127 (3):607-9., 1978 |
Brazil |
20 |
NR |
Diarrhea, abdominal pain, palpable abdominal mass |
Small intestine |
No |
No |
Antifungal therapy |
Recovery |
Moderate |
Avritchir3939 Avritchir Y, Perroni AA. Radiological manifestations of small intestinal South American blastomycosis. Radiology. 1978;127 (3):607-9., 1978 |
Brazil |
36 |
M |
Diarrhea, hematochezia, abdominal pain, oral ulcers |
Mouth, small intestine |
No |
No |
NR |
NR |
Low |
Fernández4040 Celestino Fernández J, Castillo Rosales T, Osorio Naupari M, Ayala E, Caller I, Purón Del Aguilla R. South American blastomycosis. Colonoscopic diagnosis. Arch Gastroenterol. 1979;16(1):24-9., 1979 |
Peru |
23 |
M |
Diarrhea, hematochezia, abdominal pain |
Small and large intestine |
No |
Yes |
NR |
NR |
Low |
Fernández4040 Celestino Fernández J, Castillo Rosales T, Osorio Naupari M, Ayala E, Caller I, Purón Del Aguilla R. South American blastomycosis. Colonoscopic diagnosis. Arch Gastroenterol. 1979;16(1):24-9., 1979 |
Peru |
63 |
M |
Increased frequency of bowel movements |
Large intestine |
No |
No |
NR |
NR |
Moderate |
Neves-Silva4141 Neves-Silva R, Fernandes PM, Santos-Silva AR, Vargas PA, de Souza Cavalcante R, Lopes MA. Unusual intestinal involvement by paracoccidioidomycosis diagnosed after oral manifestation. Mycopathologia. 2018;183(6): 987-93., 2018 |
Brazil |
36 |
M |
Weight loss, diarrhea, vomiting, oral ulcers, dysphagia |
Mouth, small and large intestine, rectum |
No |
No |
ICZ, SI |
Recovery |
High |
Martinez4242 Martinez R, Rossi MA. Paracoccidioidomicose duodenal com sangramento digestivo. Rev Inst Med Trop Sao Paulo. 1984;26 (3):160-4., 1984 |
Brazil |
35 |
F |
Anorexia, fatigue, weight loss, diarrhea, hematochezia, vomiting, abdominal pain, fever, hepatomegaly, jaundice |
Esophagus, small and large intestine |
No |
No |
NR |
Death |
High |
León4343 León M, Alave J, Bustamante B, Cok J, Gotuzzo E, Seas C. Human T lymphotropic virus 1 and paracoccidioidomycosis: a probable association in Latin America. Clin Infect Dis. 2010;51 (2):250-1., 2010 |
Peru |
66 |
M |
Weight loss, dyspnea; dry cough, oral lesions |
Mouth |
No |
No |
ICZ |
Recovery |
Moderate |
León4343 León M, Alave J, Bustamante B, Cok J, Gotuzzo E, Seas C. Human T lymphotropic virus 1 and paracoccidioidomycosis: a probable association in Latin America. Clin Infect Dis. 2010;51 (2):250-1., 2010 |
Peru |
34 |
M |
Weight loss, diarrhea, oral ulcers, odynophagia, dry cough |
Mouth, small and large intestine |
No |
No |
ICZ, AmB |
Recovery |
Moderate |
León4343 León M, Alave J, Bustamante B, Cok J, Gotuzzo E, Seas C. Human T lymphotropic virus 1 and paracoccidioidomycosis: a probable association in Latin America. Clin Infect Dis. 2010;51 (2):250-1., 2010 |
Peru |
40 |
F |
Weight loss, diarrhea, hepatomegaly |
Large intestine |
No |
No |
AmB |
Death |
Moderate |