Effect of prodigiosin on the alleviation of the intestinal inflammation of weaned rats based on ¹H-NMR spectroscopy study and biochemistry indexes

FIGURE 1
Effect of PG on the body mass.

FIGURE 2
Effect of PG on the contents of feces moisture.

FIGURE 3
¹H-NMR spectra of the feces metabolites from the control group and PG group.

FIGURE 4
Multivariate statistical analysis of ¹H-NMR spectra data sets of the feces contents of weaned rats. Each point in A, B, and D represented one sample. A represented the PCA score of the 1H-NMR spectrum dataset of the cecal contents; B and C respectively represented the PLS-DA model score and the permutation verification; D and E represented the score and load diagram of the OPLS-DA model respectively. The original point in C represented the R² value of the model. The square point represented the model Q² value. Each point in E represented the chemical shift value with the integral interval.

FIGURE 5
Effect of PG on the accumulation of organic acids in the cecal of weaned rats.

FIGURE 6
Effect of PG on the contents of free ammonia.

FIGURE 7
The effect of PG on the jejunum morphology of weaned rats. Note: A: control group; B: PG group. In the Figure 7A, the box and ellipse areas pointed by the arrow were the inflammatory areas. Correspondingly, no inflammatory area was detected in the Figure 7B after feeding PG.