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Pharmaceutical interventions arising from the review of pharmacotherapy in hospital patients with COVID-19

Abstract

To characterize the main pharmaceutical interventions performed by reviewing the pharmacotherapy of hospital patients with COVID-19. This is a study carried out in a hospital center in the northern region of Santa Catarina, in which data were collected on pharmaceutical interventions resulting from the review of the pharmacotherapy of hospital patients with COVID-19, between April 2020 and June 2021. During the study period, a total of 16,675 medical presciptions were validated by pharmacists in theselected hospitalization sectors. These validations resulted in 1,108 pharmaceutical interventions, with the largest number related to drug dose adjustment (25.9%). Among the drugs, the class with the highest number of interventions was antimicrobials, especially Azithromycin with 23.5% of interventions performed, followed by Teicoplanin 23.9% and Meropenem 18.6%. Pharmaceutical interventions due to kidney function were also highlighted, as the disease is not restricted to damage to the respiratory system, but also presents complications in other organs, such as the kidneys. Through the review of pharmacotherapy and the pharmaceutical interventions resulting from this activity, clinical pharmacists played a key role in optimizing pharmacotherapy, in addition to promoting the safe use of medications.

Keywords:
COVID-19; SARS-CoV-2 virus; Clinical pharmacy; Pharmaceutical care; Pharmaceutical services

Universidade de São Paulo, Faculdade de Ciências Farmacêuticas Av. Prof. Lineu Prestes, n. 580, 05508-000 S. Paulo/SP Brasil, Tel.: (55 11) 3091-3824 - São Paulo - SP - Brazil
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