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Prevalence of Urinary Symptoms and Predictive Factors in Kidney Transplant Patients in a Brazilian Center

ABSTRACT

Objectives:

Identify relationships between voiding symptom scores and variables related to transplantation.

Methods:

Observational, cross-sectional, and analytical study, in which all patients undergoing kidney transplantation in the state of Rondônia, Brazil, were evaluated through interviews and analysis of records, regarding their clinical-demographic profile and signs and symptoms of voiding dysfunction. Chi-square, analysis of variance (ANOVA), and multivariate linear regression were used to establish possible correlations.

Results:

Eight-one point eighty-seven percent of patients were approached (n = 122). The most common symptoms were increased frequency (68.2%) and nocturia (97.6%). ANOVA demonstrated a relationship between age and International Consultation on Incontinence Questionnaire (ICIQ) (p = 0.014), alcoholism and Overactive Bladder Questionnaire (OAB) (p = 0.001), immunosuppressive regimen and ICIQ (p = 0.04), thymoglobulin and OAB (p = 0.009), use of double J and ICIQ (p = 0.014), citomegalovirus infection and OAB (p = 0.031), and International Prostate Symptom Score (IPSS) (p = 0.008). Of the comorbidities, it was observed heart failure related to OAB (p = 0.009) and ICIQ (p = 0.003) scores. Chi-square showed an association between alcohol use and group 1 of the OAB (p = 0.005). The Pearson test positively correlated graft ischemia time with ICIQ (p = 0.04).

Conclusion:

The prevalence of lower urinary tract symptoms is higher in kidney transplant recipients than in the general population, and it was possible to determine predictive factors for their occurrence.

Descriptors
Organ Transplantation; Kidney Transplantation; Miction; Urinary Bladder Overactive; Urinary Incontinence

Associação Brasileira de Transplante de Órgãos Avenida Paulista, 2.001 - 17° andar Conj. 1.704/1.707, Cerqueira César - CEP: 01311-300, Tel: (55) 11 98243 - 3901 - São Paulo - SP - Brazil
E-mail: abto@abto.org.br