ABSTRACT
BACKGROUND AND OBJECTIVES:
Despite the ancestral use of cannabinoids in adults, safety and efficacy in children is unclear. The impact of cannabis on the developing brain is unknown1 While studies conducted in adults can provide insight into the efficacy/toxicity profile of cannabis, there is a need for specific studies in children and adolescents to understand the impact of cannabis on the developing brain, as well as the potential long-term effects of cannabis use. The objective of this study was to bring a comprehensive view and critical discussion on the subject.
CONTENTS:
A narrative review based on research in the Pubmed, Medline and Scielo databases was prepared, with an open theme and a selective literature review in the context of the pediatric population.
CONCLUSION:
Current research on the impact of medical cannabis use in children and adolescents remains limited4, which reinforces the need for robust studies in this population.
Keywords:
Cancer; Medical cannabis; Pediatrics
HIGHLIGHTS
The impact of cannabis on the developing brain is unknown.
The role of the endocannabinoid system in mediating neural and cognitive function is not restricted to gestation or early childhood.
There is a need for robust studies on safety and efficacy in the pediatric population.