Abstract
Background
Drug-Resistant Tuberculosis (DRTB) is one of the most relevant challenge to public health.
Objective
This study analyzed the temporal trend of the DRTB and resistance types in the state of Pernambuco, from 2002 to 2014.
Method
This was an observational study of the temporal trend type of a historical series using data from the Special Treatment Information System of Tuberculosis (SITE-TB) and also analysis by the autoregressive moving average models of order 2.
Results
A total of 298 new DRTB cases were reported, ranging from 0.06 to 0.71 per 100,000 inhabitants. At least one case was reported in 40 of the 185 municipalities in the state. The temporal trend of DRTB and the proportion between resistance types did not present a linear behavior. In the last 5 years, there has been an upward trend, concentrating 71.1% of the historical series. In 2014, there was an expressive growth of both primary and secondary DRTB, when compared to the year 2002.
Conclusion
Despite the low incidence and tendency of DRTB not to be linear, the increase in cases in the last years of the historical series can be considered as a warning sign for the disease control programs of Pernambuco.
Keywords:
tuberculosis; multidrug-resistant tuberculosis; epidemiology; time series studies
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