Figure 2
ROC curves for the prognosis of early (A) and late (B) mortality among patients with sepsis and septic shock. A: AUC demonstrates that serum PCT measures 0.634 (95% CI, 0.586-0.682), hs-CRP measures 0.640 (95% CI, 0.587-0.692), WBC measures 0.595 (95% CI, 0.536-0.654), SOFA score measures 0.805 (95% CI, 0.763-0.847), MEDS score measures 0.761 (95% CI, 0.715-0.807), LODS score measures 0.785 (95% CI, 0.742-0.827), and APACHE II score measures 0.778 (95% CI, 0.736-0.821) for the prognosis of early mortality. B: AUC demonstrates that serum PCT measures 0.596 (95% CI, 0.548-0.645), hs-CRP measures 0.605 (95% CI, 0.555-0.656), WBC measures 0.586 (95% CI, 0.532-0.640), SOFA score measures 0.754 (95% CI, 0.709-0.799), MEDS score measures 0.744 (95% CI, 0.699-0.788), LODS score measures 0.755 (95% CI, 0.711-0.799), and APACHE-II score measures 0.774 (95% CI, 0.734-0.815) for prognosis of late mortality. ROC, receiver operating characteristic; AUC, area under the curve; PCT, procalcitonin; CI, confidence interval; hs-CRP, high sensitivity C-reactive protein; WBC, white blood cell; SOFA, Sequential organ failure assessment; LODS, Logistic organ dysfunction system; MEDS, Mortality in emergency department sepsis; APACHE-II, Acute Physiology and Chronic Health Evaluation II.
Figure 3
ROC curves for serum PCT, hs-CRP, and WBC. A: AUC demonstrates that serum PCT measures 0.718 (95% CI, 0.648-0.788), hs-CRP measures 0.614 (95% CI, 0.543-0.682), and WBC measures 0.588 (95% CI, 0.497-0.679) for the prognosis of early mortality of patients with sepsis and septic shock caused by GPB infections. B: AUC demonstrates that serum PCT measures 0.583 (95% CI, 0.507-0.659), hs-CRP measures 0.603 (95% CI, 0.520-0.686), and WBC measures 0.608 (95% CI, 0.518-0.697) for the prognosis of early mortality of patients with sepsis and septic shock caused by GNB infections. C: AUC demonstrates that serum PCT measures 0.678 (95% CI, 0.603-0.753), hs-CRP measures 0.600 (95% CI, 0.529-0.669), and WBC measures 0.587 (95% CI, 0.515-0.656) for the prognosis of late mortality in patients with sepsis and septic shock caused by GPB infections. D: AUC demonstrates that serum PCT measures 0.547 (95% CI, 0.473-0.621); hs-CRP, 0.588 (95% CI, 0.510-0.667), and WBC measures 0.570 (95% CI, 0.487-0.652) for the prognosis of late mortality of patients with sepsis and septic shock caused by GNB infections. ROC, receiver operating characteristic; PCT, procalcitonin; hs-CRP, high-sensitivity C-reactive protein; WBC, white blood cell; AUC, area under the curve; CI, confidence interval; GPB, gram-positive bacteria; GNB, gram-negative bacteria.
Figure 4
ROC curves for SOFA, LODS, MEDS, and APACHE-II. A: AUC demonstrates that SOFA measures 0.782 (95% CI, 0.709-0.854), LODS was 0.756 (95% CI, 0.687-0.826), 0.739 (95%CI, 0.669-0.808), and APACHE II measures 0.814 (95% CI, 0.754-0.874) for the prognosis of early mortality of patients with sepsis and septic shock caused by GPB infections. B: AUC demonstrates that SOFA measures 0.731 (95% CI, 0.657-0.805), LODS measures 0.723 (95% CI, 0.652-0.794), MEDS was 0.724 (95%CI, 0.654-0.794), and APACHE II measures 0.780 (95% CI, 0.718-0.843) for the prognosis of late mortality in patients with sepsis and septic shock caused by GPB infections. C: AUC demonstrates that SOFA measures 0.806 (95% CI: 0.747-0.864), LODS measures 0.796 (95% CI, 0.736-0.857), MEDS measures 0.807 (95%CI, 0.746-0.867), and APACHE II measures 0.761 (95% CI, 0.697-0.825) for the prognosis of early mortality in patients with sepsis and septic shock caused by GNB infections. D: AUC demonstrates that SOFA measures 0.782 (95% CI, 0.723-0.842), LODS was 0.795 (95% CI, 0.736-0.853), 0.796 (95% CI, 0.736-0.855), and APACHE II measures 0.783 (95% CI, 0.724-0.842) for the prognosis of late mortality in patients with sepsis and septic shock caused by GNB infections. ROC, receiver operating characteristic; PCT, procalcitonin; hs-CRP, high-sensitivity C-reactive protein; WBC, white blood cell; AUC, area under the curve; CI, confidence interval; GPB, gram-positive bacteria; GNB, gram-negative bacteria.