1 |
Khalfa et al. (2004)(2525 Khalfa S, Bruneau N, Rogé B, Georgieff N, Veuillet E, Adrien JL, et al. Increased perception of loudness in autism. Hear Res. 2004;198(1-2):87-92. http://dx.doi.org/10.1016/j.heares.2004.07.006. PMid:15617227. http://dx.doi.org/10.1016/j.heares.2004....
) HPA |
GASD=11 CG=11 9-17 years old |
Questioning relatives |
Auditory – Psychoacoustics |
- thresholds for pure tones with no difference between groups - GASD show measures of discomfort thresholds and dynamic field of hearing, smaller than CG - HPA in 63.0% in GASD vs. 27.0% CG - The dynamic field of hearing was lower at 4 and 8 kHz, regardless of the group |
2 |
Danesh and Kaf (2012)(1616 Danesh AA, Kaf WA. DPOAEs and contralateral acoustic stimulation and their link to sound hypersensitivity in children with autism. Int J Audiol. 2012;5(4):345-52. http://dx.doi.org/10.3109/14992027.2011.626202. PMid:22299666. http://dx.doi.org/10.3109/14992027.2011....
) HSA |
GASD = 18 CG = 12 6-14 years old X = 8 |
Not used |
1. Evoked Otoacoustic Emissions (EOAE) Sensory response – inner ear 2. Inhibitory effect of emissions otoacoustic Sensory neural/subcortical response |
- GASD show lower amplitudes of response than CG - GASD showed lower values of the suppression effect than CG and they were higher for the left ear than to the right - The lower the age the greater the suppression value, without differences between the ages in each of the groups |
3 |
Matsuzaki et al. (2012)(3737 Matsuzaki J, Kagitani-Shimono K, Goto T, Sanefuji W, Yamamoto T, Sakai S, et al. Differential responses of primary auditory cortex in autistic spectrum disorder with auditory hypersensitivity. Neuroreport. 2012;23(2):113-8. http://dx.doi.org/10.1097/WNR.0b013e32834ebf44. PMid:22146579. http://dx.doi.org/10.1097/WNR.0b013e3283...
) HSA |
GASD = 18 X = 9 years old GC = 12 X = 10 years old |
Infant/Toddler Sensory Profile (Dunn, 2002)
(
38
38 Dunn W. Infant/toddler sensory profile. San Antonio, TX: The Psychological Corporation; 2002.
)
|
Auditory – magnetoencephalography |
- The score of the questionnaire defined the presence of AHS and subdivided the GASD in with and without AHS - Amplitude measurements of the M50 and M100 components were not different between the groups, regardless of the questionnaire score - Latency of the M50 had a difference only between GASD and AHS when compared with CG - Latency of the M100, there was a difference between the three GASD groups with AHS > GASD without AHS > CG |
4 |
Thabet and Zaghloul (2013)(3939 Thabet EM, Zaghloul HS. Auditory profile and high resolution CT scan in autism spectrum disorders children with auditory hypersensitivity. Eur Arch Otorhinolaryngol. 2013;270(8):2353-8. http://dx.doi.org/10.1007/s00405-013-2482-4. PMid:23580033. http://dx.doi.org/10.1007/s00405-013-248...
) HSA |
GASD =14 CG =15 2-8 years X= 3 years ± 1 |
Informal reporting of relatives |
1. ABR Neural response – subcortical 2. Image − Internal ear tomography |
- Electrophysiological threshold with no difference between groups - Absolute latencies of components I and III and interpeak latencies I – III, with no differences between groups - Absolute latency of early GASD component V and intervals III – V and I – V with lower values than CG - 29% of GASD showed images compatible with dehiscence of the semicircular canals |
5 |
Bhatara et al. (2013)(77 Bhatara A, Babikian T, Laugeson E, Tachdjian R, Sininger Y. Impaired timing and frequency discrimination in high-functioning autism spectrum disorders. J Autism Dev Disord. 2013;43(10):2312-28. http://dx.doi.org/10.1007/s10803-013-1778-y. PMid:23386117. http://dx.doi.org/10.1007/s10803-013-177...
) HSA |
GASD =17 CG =17 X=10-14 years old |
1. Sensory Profile (Dunn, 1999)
(
40
40 Dunn W. Sensory profile. San Antonio, TX: The Psychological Corporation; 1999.
)
2. Adolescent/adult sensory profile (Dunn, 2002)
(
38
38 Dunn W. Infant/toddler sensory profile. San Antonio, TX: The Psychological Corporation; 2002.
)
|
Auditory – psychoacoustics |
- Adolescents with ASD presented higher scores in sensory profile than neurotypical (NT) group - The group with ASD requires a greater ratio signal-noise than control group to understand the words in the speech with noise test - Group with ASD: impaired frequency discrimination |
6 |
Bhatara et al. (2013)(4141 Bhatara A, Quintin EM, Fombonne E, Levitin DJ. Early sensitivity to sound and musical preferences and enjoyment in adolescents with autism spectrum disorders. Psychomusicology. 2013;32(2):100-8. http://dx.doi.org/10.1037/a0033754. http://dx.doi.org/10.1037/a0033754...
) HSA |
GASD =33 CG=35 10-19 years old |
1. Salk and McGill Musical Inventory
|
Not used |
- Adolescents with ASD (68%) showed auditory hypersensitivity in childhood more frequently than in control group (17%). - Even with hypersensitivity, the interest in music in individuals with ASD was the same as in control group - Verbal performance and IQ do not predict auditory hypersensitivity, as well as chronological age also showed a negative correlation to hypersensitivity. |
7 |
Thabet (2014)(4242 Thabet EM. Ocular vestibular evoked myogenic potentials n10 response in autism spectrum disorders children with auditory hypersensitivity: an indicator of semicircular canal dehiscence. Eur Arch Otorhinolaryngol. 2014;271(5):1283-8. http://dx.doi.org/10.1007/s00405-013-2736-1. PMid:24100882. http://dx.doi.org/10.1007/s00405-013-273...
) HSA |
GASD =14 CG =15 2-4 years old |
Not applicable |
Not used |
- Study Group: VEMP amplitude increase in five subjects - VEMP showed diagnostic capability in the differentiation of hypersensitivity caused by semicircular canal dehiscence syndrome or by atypical cortical development. |
8 |
Matsuzaki et al. (2014)(4343 Matsuzaki J, Kagitani-Shimono K, Sugata H, Hirata M, Hanaie R, Nagatani F, et al. Progressively increased M50 responses to repeated sounds in autism spectrum disorder with auditory hypersensitivity: a magnetoencephalographic study. PLoS One. 2014;9(7):e102599. http://dx.doi.org/10.1371/journal.pone.0102599. PMid:25054201. http://dx.doi.org/10.1371/journal.pone.0...
) HSA |
GASD =21 CG =15 X= 9 years old ± 1 |
1. Infant/Toddler Sensory Profile (Dunn, 2002)
(
38
38 Dunn W. Infant/toddler sensory profile. San Antonio, TX: The Psychological Corporation; 2002.
)
|
Magnetoencephalography |
- Group with ASD and auditory hypersensitivity showed more prolonged responses with latencies (M50/M100) than other groups; - Latency was shown to be significantly related to the severity of auditory hypersensitivity |
9 |
Donkers et al. (2015)(4444 Donkers FC, Schipul SE, Baranek GT, Cleary KM, Willoughby MT, Evans AM, et al. Attenuated auditory event-related potentials and associations with atypical sensory response patterns in children with autism. J Autism Dev Disord. 2015;45(2):506-23. http://dx.doi.org/10.1007/s10803-013-1948-y. PMid:24072639. http://dx.doi.org/10.1007/s10803-013-194...
) AHR |
GASD =29 CG =30 4-12 years old |
1. The Sensory the Tactile Defensiveness
2. Discrimination Test-Revised
3. Sensory Processing Assessment for Young 4. Sensory Experiences Questionnaire
5. Sensory Profile
|
LLAEP Neural responses -subcortical and cortical |
- It was observed for standard sounds, the relation between wave P1 and N2: P1 responses greater and N2 attenuated, auditory more severe hyper-responsiveness. - P1 attenuated and N2 attenuated, - lighter hyper-responsiveness. |
10 |
Danesh et al. (2015)(2929 Danesh AA, Lang D, Kaf W, Andreassen WD, Scott J, Eshraghi AA. Tinnitus and hyperacusis in autism spectrum disorders with emphasis on high functioning individuals diagnosed with Asperger’s Syndrome. Int J Pediatr Otorhinolaryngol. 2015;79(10):1683-8. http://dx.doi.org/10.1016/j.ijporl.2015.07.024. PMid:26243502. http://dx.doi.org/10.1016/j.ijporl.2015....
) AHR |
GASD =55 4-42 years old X=17 years old |
1. Hyperacusis Questionnaire (Khalfa et al., 2002)(4545 Khalfa S, Dubal S, Veuillet E, Perez-Diaz F, Jouvent R, Collet L. Psychometric normalization of a hyperacusis questionnaire. ORL J Otorhinolaryngol Relat Spec. 2002;64(6):436-42. http://dx.doi.org/10.1159/000067570. PMid:12499770. http://dx.doi.org/10.1159/000067570...
)
|
Not used |
- 69% of the subjects reported hyperacusis - 35% reported buzzing sound - Higher prevalence of hyperacusis and buzzing sound in the population with ASD than in general population. |
11 |
Green et al. (2015)(4646 Green SA, Hernandez L, Tottenham N, Krasileva K, Bookheimer SY, Dapretto M. Neurobiology of sensory overresponsivity in youth with autism spectrum disorders. JAMA Psychiatry. 2015;72(8):778-86. http://dx.doi.org/10.1001/jamapsychiatry.2015.0737. PMid:26061819. http://dx.doi.org/10.1001/jamapsychiatry...
) AHR |
GASD =19 TG = 19 9-17 years old X = 14 |
1. Short Sensory Profile.
2. Sensory Over-Responsivity Scales (SORS)
|
Functional resonance |
- There was no difference in activity activation between the groups for auditory stimulation, but for tactile and for concomitant stimulation, GASD showed a higher response than CG. - There was a positive correlation between SORS score and activation of cortical areas. - There was no difference between groups for habituation onset, but once the process began, it was slower in GASD and in GASD with SOR, it was slower for time when compared to CG GASD |
12 |
Dunlop et al. (2016)(88 Dunlop WA, Enticott PG, Rajan R. Speech discrimination difficulties in high-functioning autism spectrum disorder are likely independent of auditory hypersensitivity. Front Hum Neurosci. 2016;401(10):401. http://dx.doi.org/10.3389/fnhum.2016.00401. PMid:27555814. http://dx.doi.org/10.3389/fnhum.2016.004...
) AHR |
GASD =16 20-52 years old CG =31 19 years old |
1. Auditory Attention and Distress Questionnaire |
Auditory – psychoacoustics |
- There was a statistically significant difference between the discomfort threshold of CG and GASD with without hypersensitivity, demonstrating that the latter has lower values of auditory discomfort thresholds |
13 |
Wilson et al. (2017)(1717 Wilson US, Sadler KM, Hancock KE, Guinan JJ Jr, Lichtenhan JT. Efferent inhibition strength is a physiological correlate of hyperacusis in children with autism spectrum disorder. J Neurophysiol. 2017;118(2):1164-72. http://dx.doi.org/10.1152/jn.00142.2017. PMid:28592687. http://dx.doi.org/10.1152/jn.00142.2017...
) HPA |
GASD =18 CG=14 10-16 years old |
1. Hyperacusis Questionnaire (Khalfa et al., 2002)
(
45
45 Khalfa S, Dubal S, Veuillet E, Perez-Diaz F, Jouvent R, Collet L. Psychometric normalization of a hyperacusis questionnaire. ORL J Otorhinolaryngol Relat Spec. 2002;64(6):436-42. http://dx.doi.org/10.1159/000067570. PMid:12499770. http://dx.doi.org/10.1159/000067570...
)
|
Auditory – electroacoustic |
- Positive correlation between severity of hyperacusis and suppression of EOAE. - The suppression effect is higher in all frequencies of GASD with severe HPA when compared to GASD without severe HPA and CG. |