Whitehouse and Bishop(2323 Whitehouse AJ, Bishop DV. Do children with autism ‘switch off’ to speech sounds? An investigation using event-related potentials. Dev Sci. 2008;11:516-24.)
|
Prospective cross-sectional |
15 boys aged 7 to 14 years |
15 (11 boys) aged 7 to 14 years |
DSM-IV |
Verbal and non-verbal. Oddball Paradigm. |
For the non-verbal stimulus, there was no difference between the groups, but there was a difference for the verbal stimulus, and the SG presented reduced amplitude for the P1, N2 and P3 components. |
Analysis of amplitude only; it only presents the numerical values of the verbal stimulus; it only analyzes the P1, N2 and P3 components. |
Matas et al.(2424 Matas CG, Gonçalves IC, Magliaro FC. Audiologic and electrophysiologic evaluation in children with psychiatric disorders. Rev Bras Otorrinolaringol. 2009;75:130-8.)
|
Prospective cross-sectional |
10 (9 boys) aged 8 to 19 years |
20 (3 boys) aged 8 to 19 years |
DSM-IV |
Non-verbal (tone burst). Oddball Paradigm. |
P3 responses were altered by 15% in the CG (latency delay) and 40% in the SG (50% showed delayed latency and 50% showed no response). |
It does not present the results numerically; small sample size for the SG; evaluated only the P3 component; analyzed only the latency variable. |
Orekhova et al.(2525 Orekhova EV, Stroganova TA, Prokofiev AO, Nygren G, Gillberg C, Elam M. The right hemisphere fails to respond to temporal novelty in autism: evidence from an ERP study. Clin Neurophysiol. 2009;120:520-9.)
|
Prospective cross-sectional |
21 (17 boys) aged 4 to 8 years |
21 (18 boys) aged 4 to 8 years |
DSM-IV-TR and ICD-10 confirmed by DISCO-10 |
Non-verbal sounds presented at different intervals. Oddball Paradigm. |
The SG demonstrated reduced amplitude of N1 and N2 components. |
It does not present the results numerically; evaluated only the N1 and N2 components; evaluated only the amplitude variable. |
Russo et al.(2626 Russo NM, Zecker S, Trommer B, Chen J, Kraus N. Effects of background noise on cortical encoding of speech in autism spectrum disorders. J Autism Dev Disord. 2009;39:1185-96.)
|
Prospective cross-sectional |
16 (14 boys) aged 7 to 13 years |
11 (7 boys) aged 7 to 13 years |
ADOS and ADI-R |
Verbal with and without noise. Without using the Oddball paradigm. |
The SG showed increased latencies and decreased amplitudes of the P1 and N1 components. |
Evaluated only P1 and N1 components; small sample size for the CG. |
Magliaro et al.(44 Magliaro FC, Scheuer CI, Assumpção-Júnior FB, Matas CG. Study of auditory evoked potentials in autism. Pro Fono. 2010;22:31-6.)
|
Prospective cross-sectional |
16 (15 boys) aged 11.94 years on average |
25 (9 boys) aged 12.16 years on average |
DSM-IV |
Non-verbal (tone burst). Oddball Paradigm. |
Absence of response (60% of cases) was the predominant type of change in the SG compared with the CG (0% absence). |
It does not present the results for latency and amplitude; evaluated only the P3 component. |
Gomot et al.(2727 Gomot M, Blanc R, Clery H, Roux S, Barthelemy C, Bruneau N. Candidate electrophysiological endophenotypes of hyper-reactivity to change in autism. J Autism Dev Disord. 2011;41:705-14.)
|
Prospective cross-sectional |
27 (21 boys) aged 5 to 11 years |
27 (21 boys) aged 5 to 11 years |
DSM-IV-R |
Non-verbal (tone burst). Oddball paradigm, non-attentional. |
The SG showed decreased latency and increased amplitude values for the P3 component. |
Evaluated only the P3 component. |
Andersson et al.(2828 Andersson S, Posserud M, Lundervold AJ. Early and late auditory event-related potentials in cognitively high functioning male adolescents with autism spectrum disorder. Res Autism Spectr Disord. 2013;7:815-23.)
|
Prospective cross-sectional |
11 boys aged 16 years on average |
12 boys aged 15.3 years on average |
DISCO |
Non-verbal (tone burst). Oddball Paradigm. |
There were no differences between groups for the components analyzed (N1, P2, P3a, and P3b). |
Small sample size. |
Stroganova et al.(2929 Stroganova TA, Kozunov VV, Posikera IN, Galuta IA, Gratchev VV, Orekhova EV. Abnormal pre-attentive arousal in young children with autism spectrum disorder contributes to their atypical auditory behavior: an ERP study. PLoS One. 2013;8:e69100.)
|
Prospective cross-sectional |
10 boys aged 75.3 months on average |
19 boys aged 76.8 months on average |
DSM-IV-TR and ICD-10 |
Non-verbal Without using the Oddball paradigm |
Change in the CAEP at the level of temporal processing in the SG. There was an asymmetry in the responses of the cortical hemispheres, with those of the RH attenuated compared with those of the LH. The SG showed lower amplitude value for the P1 component when compared with that of the CG. |
It does not present the results numerically; small sample size for the SG, with a significant difference in sample size between the groups; evaluated only the P1 component. |
Azouz et al.(3030 Azouz HG, Kozou H, Khalil M, Abdou RM, Sakr M. The correlation between central auditory processing in autistic children and their language processing abilities. Int J Pediatr Otorhinolaryngol. 2014;78:2297-300.)
|
Prospective cross-sectional |
30 (23 boys) aged 5.5 years on average |
15 (unspecified gender) aged 5.5 years on average |
DSM-IV-TR and ADI-R |
Not specified. Unspecified paradigm. |
Greater latency and smaller amplitude of the N1 component in both ears in the SG compared with the CG, with components amplitude observed for the left ear. |
It does not present the results numerically; significant difference in sample size between groups; evaluated only the N1 component; did not describe the protocol for collecting and analyzing the CAEP. |
Donkers et al.(3131 Donkers FC, Schipul SE, Baranek GT, Cleary KM, Willoughby MT, Evans AM, et al. Attenuated auditory event-related potentials and associations with atypical sensory response patterns in children with autism. J Autism Dev Disord. 2015;45:506-23.)
|
Prospective cross-sectional |
28 (22 boys) aged 4 to 12 years |
39 (31 boys) aged 4 to 12 years |
ADI-R and ADOS-2 |
Non-verbal. Oddball Paradigm. |
The SG presented reduced amplitude of the P3a component. Lower latency values for the P1 and N2 components in the SG. The other components showed no statistically significant difference. |
Evaluated only the P1, N2 and P3 components. |
Gonzalez-Gadea et al.(3232 Gonzalez-Gadea ML, Chennu S, Bekinschtein TA, Rattazzi A, Beraudi A, Tripicchio P, et al. Predictive coding in autism spectrum disorder and attention deficit hyperactivity disorder. J Neurophysiol. 2015;114:2625-36.)
|
Prospective cross-sectional |
24 (23 boys) aged 8 to 15 years |
19 (15 boys) aged 8 to 15 years |
DSM-5 |
Non-verbal performed in three different presentations: frequent, rare-expected and rare-unexpected. |
P3 rare-expected for the SG: activation on the left side was greater. Rare-unexpected P3: decrease in P3 amplitude with greater activation on the right side. When comparing these results with the findings of the frequent stimulus, the only group that did not present better responses was the SG. |
It does not present the results numerically; evaluated only the P3 component. |
Sokhadze et al.(3333 Sokhadze EM, Casanova MF, Tasman A, Brockett S. Electrophysiological and behavioral outcomes of berard Auditory Integration Training (AIT) in children with autism spectrum disorder. Appl Psychophysiol Biofeedback. 2016;41:405-20.)
|
Prospective Longitudinal |
18 (15 boys) aged 11 years on average |
16 (12 boys) aged 12 years on average |
DSM-IV-TR and ADI-R |
Non-verbal. Oddball Paradigm. |
Pre-training: increased latency values of the N1, P3a and P3b components in the SG. |
It does not present the results numerically; evaluated only the N1, P3a and P3b components. |
Post-Training: latency decreased in the SG, but was still increased compared with the CG. The amplitude of P3a decreased in the SG, and difference compared with the CG was no longer observed. |
Galilee et al.(3434 Galilee A, Stefanidou C, McCleery JP. Atypical speech versus non-speech detection and discrimination in 4- to 6- yr old children with autism spectrum disorder: an ERP study. PLoS One. 2017;12:e0181354.)
|
Prospective cross-sectional |
14 (12 boys) aged 4 to 6 years |
14 (12 boys) aged 4 to 6 years |
ADOS-G |
Verbal and non-verbal, with a new paradigm of repetition pairs. Oddball Paradigm. |
The SG detected and discriminated verbal and non-verbal stimuli similarly to the CG (N330 and P350); however, the SG used only the LH for this processing, unlike the CG, which used both hemispheres. |
It does not present the results numerically; small sample size; evaluated only the N330 and P350 components. |
Kamita(3535 Kamita MK. Brainstem evoked response auditory and long-latency auditory evoked potential in children with autism spectrum disorder [dissertation]. São Paulo: Faculdade de Medicina, Universidade de São Paulo; 2017.)
|
Prospective cross-sectional |
15 (13 boys) aged 7 to 12 years |
15 (13 boys) aged 7 to 12 years |
Not specified |
Verbal and non-verbal. Oddball Paradigm |
No statistically significant difference was found between the groups. |
There is no diagnostic criterion for ASD. |
Lortie et al.(3636 Lortie M, Proulx-Bégin L, Saint-Amour D, Cousineau D, Théoret H, Lepage JF. Brief report: biological sound processing in children with autistic spectrum disorder. J Autism Dev Disord. 2017;47:1904-9.)
|
Prospective cross-sectional |
10 (9 boys) aged 6 years on average |
12 (8 boys) aged 6 years on average |
DSM-IV-TR |
Biological sounds and control stimuli with P3 component analysis with involuntary attentional guidance. Oddball Paradigm. |
The SG presented higher latency for biological sounds than the CG; however, the SG presented lower latency for the control stimuli compared with the CG. |
It does not present the results numerically; small sample size; evaluated only the P3 component; evaluated only the latency. |