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Canine mammary tumors: hormonal influence and effects of ovariohiysterectomy as an adjuvant therapy

The mammary neoplasms comprises aproximatel 50% ofthe diagnosed tumor s m the bitch. Although female sexual honnones play a fundamental role in the development of these tumors in mammals, the value of the suppression hormonal (ovariohysterectomy) as an adjuvam treatment remains controversial. There are still arguments on whether the ovariohysterectomy after diagnosis of the tumor possesses influences lhe growth and progression of the tumor on the affected gland or on other mammary glands. The objective ofthis review is to discuss some aspects related to the hormonal influence in the pathogenesis of the canine tumor, as well as the therapeutic value ofspaying. when accomplished in the moment ofthe mastectomy.

mammary tumor; bitches; sexual steroid honnones; mastectomy; ovariohysterectomy


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