Conventional
|
Terpenes |
Cafestol |
Anti-inflammation, hepatoprotective, anticancer, antidiabetic, and anti-osteoclastogenesis activities (Ren et al., 2019Ren, Y., Wang, C., Xu, J., & Wang, S. (2019). Cafestol and kahweol: a review on their bioactivities and pharmacological properties. International Journal of Molecular Sciences, 20(17), 4238. http://dx.doi.org/10.3390/ijms20174238. PMid:31480213. http://dx.doi.org/10.3390/ijms20174238...
) |
Andrographolide |
Antiviral (Adiguna et al., 2021Adiguna, S. P., Panggabean, J. A., Atikana, A., Untari, F., Izzati, F., Bayu, A., Rosyidah, A., Rahmawati, S. I., & Putra, M. Y. (2021). Antiviral activities of andrographolide and its derivatives: mechanism of action and delivery system. Pharmaceuticals, 14(11), 1102. http://dx.doi.org/10.3390/ph14111102. PMid:34832884. http://dx.doi.org/10.3390/ph14111102...
). |
Polyphenols |
7-Hydroxycoumarine |
Antiulcerogenic antidiarrheal and antibacterial (Cruz et al., 2020Cruz, L. F., Figueiredo, G. F., Pedro, L. P., Amorin, Y. M., Andrade, J. T., Passos, T. F., Rodrigues, F. F., Souza, I. L. A., Gonçalves, T. P. R., Dos Santos Lima, L. A. R., Ferreira, J. M. S., & Araújo, M. G. F. (2020). Umbelliferone (7-hydroxycoumarin): a non-toxic antidiarrheal and antiulcerogenic coumarin. Biomedicine and Pharmacotherapy, 129, 110432. http://dx.doi.org/10.1016/j.biopha.2020.110432. PMid:32768935. http://dx.doi.org/10.1016/j.biopha.2020....
). |
4-Methoxycinnamic acid |
Anticancer (Hasibuan et al., 2020Hasibuan, P. A. Z., Harahap, U., Sitorus, P., & Satria, D. (2020). The anticancer activities of Vernonia amygdalina Delile. Leaves on 4T1 breast cancer cells through phosphoinositide 3-kinase (PI3K) pathway. Heliyon, 6(7), e04449. http://dx.doi.org/10.1016/j.heliyon.2020.e04449. PMid:32715129. http://dx.doi.org/10.1016/j.heliyon.2020...
). |
Vanillin |
Antibacterial (Retnosari et al., 2021Retnosari, R., Rachman, I. B., Sutrisno, S., Sari, M. E. F., Sukarianingsih, D., & Rukayadi, Y. (2021). The antibacterial activity of vanillin derivative compounds. AIP Conference Proceedings, 2349(1), 020073. http://dx.doi.org/10.1063/5.0051523. http://dx.doi.org/10.1063/5.0051523...
). |
Shogaol |
Antimicrobial (Rampogu et al., 2018Rampogu, S., Baek, A., Gajula, R. G., Zeb, A., Bavi, R. S., Kumar, R., Kim, Y., Kwon, Y. J., & Lee, K. W. (2018). Ginger (Zingiber officinale) phytochemicals-gingerenone-A and shogaol inhibit SaHPPK: Molecular docking, molecular dynamics simulations and in vitro approaches. Annals of Clinical Microbiology and Antimicrobials, 17(1), 16. http://dx.doi.org/10.1186/s12941-018-0266-9. PMid:29609660. http://dx.doi.org/10.1186/s12941-018-026...
). |
Quercetin-3β-D-glucoside |
Anticarcinogenic agent (Razavi et al., 2009Razavi, S. M., Zahri, S., Zarrini, G., Nazemiyeh, H., & Mohammadi, S. (2009). Biological activity of quercetin-3-O-glucoside, a known plant flavonoid. Bioorganicheskaia khimiia, 35(3), 414-416. http://dx.doi.org/10.1134/S1068162009030133. PMid:19621057. http://dx.doi.org/10.1134/S1068162009030...
). |
Phloretin |
Antimicrobial (Barreca et al., 2014Barreca, D., Bellocco, E., Laganà, G., Ginestra, G., & Bisignano, C. (2014). Biochemical and antimicrobial activity of phloretin and its glycosilated derivatives present in apple and kumquat. Food Chemistry, 160, 292-297. http://dx.doi.org/10.1016/j.foodchem.2014.03.118. PMid:24799241. http://dx.doi.org/10.1016/j.foodchem.201...
). |
Acetophenone |
Antioxidant agent (Emami et al., 2018Emami, S., Esmaili, Z., Dehghan, G., Bahmani, M., Hashemi, S. M., Mirzaei, H., Shokrzadeh, M., & Moradi, S. E. (2018). Acetophenone benzoylhydrazones as antioxidant agents: synthesis, in vitro evaluation and structure-activity relationship studies. Food Chemistry, 268, 292-299. http://dx.doi.org/10.1016/j.foodchem.2018.06.083. PMid:30064761. http://dx.doi.org/10.1016/j.foodchem.201...
). |
Dibenzylamine |
Antibiotic (Dinarvand & Spain, 2021Dinarvand, M., & Spain, M. (2021). Identification of bioactive compounds from marine natural products and exploration of Structure-Activity Relationships (SAR). Antibiotics (Basel, Switzerland), 10(3), 337. http://dx.doi.org/10.3390/antibiotics10030337. PMid:33810102. http://dx.doi.org/10.3390/antibiotics100...
). |
Alkaloids |
Trigonelline |
Hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and antitumor activities (Zhou et al., 2012Zhou, J., Chan, L., & Zhou, S. (2012). Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease. Current Medicinal Chemistry, 19(21), 3523-3531. http://dx.doi.org/10.2174/092986712801323171. PMid:22680628. http://dx.doi.org/10.2174/09298671280132...
). |
Piperine |
Antibacterial (Hikal, 2018Hikal, D. M. (2018). Antibacterial activity of piperine and black pepper oil. Biosciences Biotechnology Research Asia, 15(4), 877-880. http://dx.doi.org/10.13005/bbra/2697. http://dx.doi.org/10.13005/bbra/2697...
). |
Nicotinamide |
As an adjunct in many dermatological diseases because of its anti-inflammatory, antioxidant, barrier repair and protective effects (Bains et al., 2018Bains, P., Kaur, M., Kaur, J., & Sharma, S. (2018). Nicotinamide: mechanism of action and indications in dermatology. Indian Journal of Dermatology, Venereology and Leprology, 84(2), 234-237. http://dx.doi.org/10.4103/ijdvl.IJDVL_286_17. PMid:29405129. http://dx.doi.org/10.4103/ijdvl.IJDVL_28...
). |
Amino acid derivatives |
Choline |
Essential nutrient for human health (Zeisel & da Costa, 2009Zeisel, S. H., & da Costa, K. A. (2009). Choline: an essential nutrient for public health. Nutrition Reviews, 67(11), 615-623. http://dx.doi.org/10.1111/j.1753-4887.2009.00246.x. PMid:19906248. http://dx.doi.org/10.1111/j.1753-4887.20...
). |
Betaine |
Anti-inflammatory (Zhao et al., 2018Zhao, G., He, F., Wu, C., Li, P., Li, N., Deng, J., Zhu, G., Ren, W., & Peng, Y. (2018). Betaine in inflammation: Mechanistic aspects and applications. Frontiers in Immunology, 9, 1070. http://dx.doi.org/10.3389/fimmu.2018.01070. PMid:29881379. http://dx.doi.org/10.3389/fimmu.2018.010...
). |
Total
|
15 compounds |
|
MAE
|
Terpenes |
Cafestol |
Antiinflammation, hepatoprotective, anticancer, antidiabetic, and anti-osteoclastogenesis activities (Ren et al., 2019Ren, Y., Wang, C., Xu, J., & Wang, S. (2019). Cafestol and kahweol: a review on their bioactivities and pharmacological properties. International Journal of Molecular Sciences, 20(17), 4238. http://dx.doi.org/10.3390/ijms20174238. PMid:31480213. http://dx.doi.org/10.3390/ijms20174238...
). |
Andrographolide |
Antiviral (Adiguna et al., 2021Adiguna, S. P., Panggabean, J. A., Atikana, A., Untari, F., Izzati, F., Bayu, A., Rosyidah, A., Rahmawati, S. I., & Putra, M. Y. (2021). Antiviral activities of andrographolide and its derivatives: mechanism of action and delivery system. Pharmaceuticals, 14(11), 1102. http://dx.doi.org/10.3390/ph14111102. PMid:34832884. http://dx.doi.org/10.3390/ph14111102...
). |
Polyphenols |
7-Hydroxycoumarine |
Antiulcerogenic antidiarrheal and antibacterial (Cruz et al., 2020Cruz, L. F., Figueiredo, G. F., Pedro, L. P., Amorin, Y. M., Andrade, J. T., Passos, T. F., Rodrigues, F. F., Souza, I. L. A., Gonçalves, T. P. R., Dos Santos Lima, L. A. R., Ferreira, J. M. S., & Araújo, M. G. F. (2020). Umbelliferone (7-hydroxycoumarin): a non-toxic antidiarrheal and antiulcerogenic coumarin. Biomedicine and Pharmacotherapy, 129, 110432. http://dx.doi.org/10.1016/j.biopha.2020.110432. PMid:32768935. http://dx.doi.org/10.1016/j.biopha.2020....
). |
Benzophenone |
Antifungal, anti-HIV, antimicrobial, antioxidant, antiviral and cytotoxic (Wu et al., 2014Wu, S. B., Long, C., & Kennelly, E. J. (2014). Structural diversity and bioactivities of natural benzophenones. Natural Product Reports, 31(9), 1158-1174. http://dx.doi.org/10.1039/C4NP00027G. PMid:24972079. http://dx.doi.org/10.1039/C4NP00027G...
). |
Vanillin |
Antibiotic (Bezerra et al., 2017Bezerra, C. F., Camilo, C. J., do Nascimento Silva, M. K., de Freitas, T. S., Ribeiro-Filho, J., & Coutinho, H. D. M. (2017). Vanillin selectively modulates the action of antibiotics against resistant bacteria. Microbial Pathogenesis, 113, 265-268. http://dx.doi.org/10.1016/j.micpath.2017.10.052. PMid:29107747. http://dx.doi.org/10.1016/j.micpath.2017...
). |
Acetophenone |
Antioxidant agent (Emami et al., 2018Emami, S., Esmaili, Z., Dehghan, G., Bahmani, M., Hashemi, S. M., Mirzaei, H., Shokrzadeh, M., & Moradi, S. E. (2018). Acetophenone benzoylhydrazones as antioxidant agents: synthesis, in vitro evaluation and structure-activity relationship studies. Food Chemistry, 268, 292-299. http://dx.doi.org/10.1016/j.foodchem.2018.06.083. PMid:30064761. http://dx.doi.org/10.1016/j.foodchem.201...
). |
3,5-di-tert-Butyl-4-hydroxybenzoic acid |
Antitumor (Ding et al., 2012Ding, W., Liu, Z., Tian, L., & Quan, X. (2012). Synthesis, characterization, and in vitro cytotoxicity of triorganotin 3,5-Di-tert-butyl-4-hydroxybenzoates. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 42(1), 82-87. http://dx.doi.org/10.1080/15533174.2011.609233. http://dx.doi.org/10.1080/15533174.2011....
). |
Dibenzylamine |
Antibiotic (Dinarvand & Spain, 2021Dinarvand, M., & Spain, M. (2021). Identification of bioactive compounds from marine natural products and exploration of Structure-Activity Relationships (SAR). Antibiotics (Basel, Switzerland), 10(3), 337. http://dx.doi.org/10.3390/antibiotics10030337. PMid:33810102. http://dx.doi.org/10.3390/antibiotics100...
). |
Alkaloids |
Trigonelline |
Hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and antitumor activities (Zhou et al., 2012Zhou, J., Chan, L., & Zhou, S. (2012). Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease. Current Medicinal Chemistry, 19(21), 3523-3531. http://dx.doi.org/10.2174/092986712801323171. PMid:22680628. http://dx.doi.org/10.2174/09298671280132...
). |
Piperine |
Antibacterial (Hikal, 2018Hikal, D. M. (2018). Antibacterial activity of piperine and black pepper oil. Biosciences Biotechnology Research Asia, 15(4), 877-880. http://dx.doi.org/10.13005/bbra/2697. http://dx.doi.org/10.13005/bbra/2697...
). |
Nicotinamide |
As an adjunct in many dermatological diseases because of its antiinflammatory, antioxidant, barrier repair and protective effects (Bains et al., 2018Bains, P., Kaur, M., Kaur, J., & Sharma, S. (2018). Nicotinamide: mechanism of action and indications in dermatology. Indian Journal of Dermatology, Venereology and Leprology, 84(2), 234-237. http://dx.doi.org/10.4103/ijdvl.IJDVL_286_17. PMid:29405129. http://dx.doi.org/10.4103/ijdvl.IJDVL_28...
). |
Nicotinic acid |
Antioxidant (Sinthupoom et al., 2014Sinthupoom, N., Prachayasittikul, V., Prachayasittikul, S., Ruchirawat, S., & Prachayasittikul, V. (2014). Nicotinic acid and derivatives as multifunctional pharmacophores for medical applications. European Food Research and Technology, 240, 1-17. http://dx.doi.org/10.1007/s00217-014-2354-1. http://dx.doi.org/10.1007/s00217-014-235...
). |
Amino acid derivatives |
Choline |
Essential nutrient for human health (Zeisel & da Costa, 2009Zeisel, S. H., & da Costa, K. A. (2009). Choline: an essential nutrient for public health. Nutrition Reviews, 67(11), 615-623. http://dx.doi.org/10.1111/j.1753-4887.2009.00246.x. PMid:19906248. http://dx.doi.org/10.1111/j.1753-4887.20...
). |
|
Total
|
13 compounds |
|
UAE-Bath
|
Terpenes |
Andrographolide |
Antiviral (Adiguna et al., 2021Adiguna, S. P., Panggabean, J. A., Atikana, A., Untari, F., Izzati, F., Bayu, A., Rosyidah, A., Rahmawati, S. I., & Putra, M. Y. (2021). Antiviral activities of andrographolide and its derivatives: mechanism of action and delivery system. Pharmaceuticals, 14(11), 1102. http://dx.doi.org/10.3390/ph14111102. PMid:34832884. http://dx.doi.org/10.3390/ph14111102...
). |
Polyphenols |
7-Hydroxycoumarine |
Antiulcerogenic antidiarrheal and antibacterial (Cruz et al., 2020Cruz, L. F., Figueiredo, G. F., Pedro, L. P., Amorin, Y. M., Andrade, J. T., Passos, T. F., Rodrigues, F. F., Souza, I. L. A., Gonçalves, T. P. R., Dos Santos Lima, L. A. R., Ferreira, J. M. S., & Araújo, M. G. F. (2020). Umbelliferone (7-hydroxycoumarin): a non-toxic antidiarrheal and antiulcerogenic coumarin. Biomedicine and Pharmacotherapy, 129, 110432. http://dx.doi.org/10.1016/j.biopha.2020.110432. PMid:32768935. http://dx.doi.org/10.1016/j.biopha.2020....
). |
Diaveridine |
Antibacterial (Wang et al., 2021Wang, L., Wen, L., Pan, Y., Liu, Z., Zhang, C., Yuan, Z., & Huang, L. (2021). Development of radioactive tracing coupled with LC/MS-IT-TOF methodology for the discovery and identification of diaveridine metabolites in pigs. Food Chemistry, 363, 130200. http://dx.doi.org/10.1016/j.foodchem.2021.130200. PMid:34120054. http://dx.doi.org/10.1016/j.foodchem.202...
). |
4-Methoxycinnamic acid |
Anticancer (Hasibuan et al., 2020Hasibuan, P. A. Z., Harahap, U., Sitorus, P., & Satria, D. (2020). The anticancer activities of Vernonia amygdalina Delile. Leaves on 4T1 breast cancer cells through phosphoinositide 3-kinase (PI3K) pathway. Heliyon, 6(7), e04449. http://dx.doi.org/10.1016/j.heliyon.2020.e04449. PMid:32715129. http://dx.doi.org/10.1016/j.heliyon.2020...
). |
Shogaol |
Antibacterial (Rigane et al., 2018Rigane, G., Mnif, S., & ben Salem, R. (2018). One step purification of 6-shogaol from zingiber officinale rosco, a phenolic compound having a high effectiveness against bacterial strains. Revue Roumaine de Chimie, 63(1), 5-10.). |
Acetophenone |
Antioxidant agent (Emami et al., 2018Emami, S., Esmaili, Z., Dehghan, G., Bahmani, M., Hashemi, S. M., Mirzaei, H., Shokrzadeh, M., & Moradi, S. E. (2018). Acetophenone benzoylhydrazones as antioxidant agents: synthesis, in vitro evaluation and structure-activity relationship studies. Food Chemistry, 268, 292-299. http://dx.doi.org/10.1016/j.foodchem.2018.06.083. PMid:30064761. http://dx.doi.org/10.1016/j.foodchem.201...
). |
Dibenzylamine |
Antibiotic (Dinarvand & Spain, 2021Dinarvand, M., & Spain, M. (2021). Identification of bioactive compounds from marine natural products and exploration of Structure-Activity Relationships (SAR). Antibiotics (Basel, Switzerland), 10(3), 337. http://dx.doi.org/10.3390/antibiotics10030337. PMid:33810102. http://dx.doi.org/10.3390/antibiotics100...
). |
3,5-di-tert-Butyl-4-hydroxybenzoic acid |
Antitumor (Ding et al., 2012Ding, W., Liu, Z., Tian, L., & Quan, X. (2012). Synthesis, characterization, and in vitro cytotoxicity of triorganotin 3,5-Di-tert-butyl-4-hydroxybenzoates. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 42(1), 82-87. http://dx.doi.org/10.1080/15533174.2011.609233. http://dx.doi.org/10.1080/15533174.2011....
). |
Alkaloids |
Trigonelline |
Hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities (Zhou et al., 2012Zhou, J., Chan, L., & Zhou, S. (2012). Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease. Current Medicinal Chemistry, 19(21), 3523-3531. http://dx.doi.org/10.2174/092986712801323171. PMid:22680628. http://dx.doi.org/10.2174/09298671280132...
). |
Reserpine |
Antibacterial (Negi et al., 2014Negi, J. S., Bisht, V., Bhandari, A. K., Bisht, D. S., Singh, P., & Singh, N. (2014). Quantification of reserpine content and antibacterial activity of Rauvolfia serpentina (L.) Benth. ex Kurz. African Journal of Microbiological Research, 8(2), 162-166. http://dx.doi.org/10.5897/AJMR2013.5847. http://dx.doi.org/10.5897/AJMR2013.5847...
). |
Nicotinamide |
As an adjunct in many dermatological diseases because of its antiinflammatory, antioxidant, barrier repair and protective effects (Bains et al., 2018Bains, P., Kaur, M., Kaur, J., & Sharma, S. (2018). Nicotinamide: mechanism of action and indications in dermatology. Indian Journal of Dermatology, Venereology and Leprology, 84(2), 234-237. http://dx.doi.org/10.4103/ijdvl.IJDVL_286_17. PMid:29405129. http://dx.doi.org/10.4103/ijdvl.IJDVL_28...
). |
Piperine |
Antibacterial (Hikal, 2018Hikal, D. M. (2018). Antibacterial activity of piperine and black pepper oil. Biosciences Biotechnology Research Asia, 15(4), 877-880. http://dx.doi.org/10.13005/bbra/2697. http://dx.doi.org/10.13005/bbra/2697...
). |
Amino acid derivatives |
Choline |
Essential nutrient for human health (Zeisel & da Costa, 2009Zeisel, S. H., & da Costa, K. A. (2009). Choline: an essential nutrient for public health. Nutrition Reviews, 67(11), 615-623. http://dx.doi.org/10.1111/j.1753-4887.2009.00246.x. PMid:19906248. http://dx.doi.org/10.1111/j.1753-4887.20...
). |
Betaine |
Anti-inflammatory (Zhao et al., 2018Zhao, G., He, F., Wu, C., Li, P., Li, N., Deng, J., Zhu, G., Ren, W., & Peng, Y. (2018). Betaine in inflammation: Mechanistic aspects and applications. Frontiers in Immunology, 9, 1070. http://dx.doi.org/10.3389/fimmu.2018.01070. PMid:29881379. http://dx.doi.org/10.3389/fimmu.2018.010...
). |
|
Total
|
14 compounds |
|
UAE-Probe
|
Terpenes |
Cafestol |
Antiinflammation, hepatoprotective, anticancer, antidiabetic, and anti-osteoclastogenesis activities (Ren et al., 2019Ren, Y., Wang, C., Xu, J., & Wang, S. (2019). Cafestol and kahweol: a review on their bioactivities and pharmacological properties. International Journal of Molecular Sciences, 20(17), 4238. http://dx.doi.org/10.3390/ijms20174238. PMid:31480213. http://dx.doi.org/10.3390/ijms20174238...
). |
Andrographolide |
Antiviral (Adiguna et al., 2021Adiguna, S. P., Panggabean, J. A., Atikana, A., Untari, F., Izzati, F., Bayu, A., Rosyidah, A., Rahmawati, S. I., & Putra, M. Y. (2021). Antiviral activities of andrographolide and its derivatives: mechanism of action and delivery system. Pharmaceuticals, 14(11), 1102. http://dx.doi.org/10.3390/ph14111102. PMid:34832884. http://dx.doi.org/10.3390/ph14111102...
). |
Polyphenols |
7-Hydroxycoumarine |
Antiulcerogenic antidiarrheal and antibacterial (Cruz et al., 2020Cruz, L. F., Figueiredo, G. F., Pedro, L. P., Amorin, Y. M., Andrade, J. T., Passos, T. F., Rodrigues, F. F., Souza, I. L. A., Gonçalves, T. P. R., Dos Santos Lima, L. A. R., Ferreira, J. M. S., & Araújo, M. G. F. (2020). Umbelliferone (7-hydroxycoumarin): a non-toxic antidiarrheal and antiulcerogenic coumarin. Biomedicine and Pharmacotherapy, 129, 110432. http://dx.doi.org/10.1016/j.biopha.2020.110432. PMid:32768935. http://dx.doi.org/10.1016/j.biopha.2020....
). |
Phloretin |
Antimicrobial (Barreca et al., 2014Barreca, D., Bellocco, E., Laganà, G., Ginestra, G., & Bisignano, C. (2014). Biochemical and antimicrobial activity of phloretin and its glycosilated derivatives present in apple and kumquat. Food Chemistry, 160, 292-297. http://dx.doi.org/10.1016/j.foodchem.2014.03.118. PMid:24799241. http://dx.doi.org/10.1016/j.foodchem.201...
). |
4-Methoxycinnamic acid |
Anticancer (Hasibuan et al., 2020Hasibuan, P. A. Z., Harahap, U., Sitorus, P., & Satria, D. (2020). The anticancer activities of Vernonia amygdalina Delile. Leaves on 4T1 breast cancer cells through phosphoinositide 3-kinase (PI3K) pathway. Heliyon, 6(7), e04449. http://dx.doi.org/10.1016/j.heliyon.2020.e04449. PMid:32715129. http://dx.doi.org/10.1016/j.heliyon.2020...
). |
Quercetin-3β-D-glucoside |
Anticarcinogenic agent (Razavi et al., 2009Razavi, S. M., Zahri, S., Zarrini, G., Nazemiyeh, H., & Mohammadi, S. (2009). Biological activity of quercetin-3-O-glucoside, a known plant flavonoid. Bioorganicheskaia khimiia, 35(3), 414-416. http://dx.doi.org/10.1134/S1068162009030133. PMid:19621057. http://dx.doi.org/10.1134/S1068162009030...
). |
Quercetin |
Antioxidant (Song et al., 2020Song, X., Wang, Y., & Gao, L. (2020). Mechanism of antioxidant properties of quercetin and quercetin-DNA complex. Journal of Molecular Modeling, 26(6), 133. http://dx.doi.org/10.1007/s00894-020-04356-x. PMid:32399900. http://dx.doi.org/10.1007/s00894-020-043...
). |
Acetophenone |
Antioxidant agent (Emami et al., 2018Emami, S., Esmaili, Z., Dehghan, G., Bahmani, M., Hashemi, S. M., Mirzaei, H., Shokrzadeh, M., & Moradi, S. E. (2018). Acetophenone benzoylhydrazones as antioxidant agents: synthesis, in vitro evaluation and structure-activity relationship studies. Food Chemistry, 268, 292-299. http://dx.doi.org/10.1016/j.foodchem.2018.06.083. PMid:30064761. http://dx.doi.org/10.1016/j.foodchem.201...
). |
Dibenzylamine |
Antibiotic (Dinarvand & Spain, 2021Dinarvand, M., & Spain, M. (2021). Identification of bioactive compounds from marine natural products and exploration of Structure-Activity Relationships (SAR). Antibiotics (Basel, Switzerland), 10(3), 337. http://dx.doi.org/10.3390/antibiotics10030337. PMid:33810102. http://dx.doi.org/10.3390/antibiotics100...
). |
Caffeic acid |
Antioxidant, antiinflammatory and anticarcinogenic (Espíndola et al., 2019Espíndola, K. M. M., Ferreira, R. G., Narvaez, L. E. M., Silva Rosario, A. C. R., da Silva, A. H. M., Silva, A. G. B., Vieira, A. P. O., & Monteiro, M. C.. (2019). Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma. Frontiers in Oncology, 9(JUN), 541. http://dx.doi.org/10.3389/fonc.2019.00541. PMid:31293975. http://dx.doi.org/10.3389/fonc.2019.0054...
). |
2-Hydroxycinnamic acid |
Antioxidant, antimicrobial, anticancer and antiinflammatory (Sova & Saso, 2020Sova, M., & Saso, L. (2020). Natural sources, pharmacokinetics, biological activities and health benefits of hydroxycinnamic acids and their metabolites. Nutrients, 12(8), 2190. http://dx.doi.org/10.3390/nu12082190. PMid:32717940. http://dx.doi.org/10.3390/nu12082190...
). |
3,5-di-tert-Butyl-4-hydroxybenzoic acid |
Antitumor (Ding et al., 2012Ding, W., Liu, Z., Tian, L., & Quan, X. (2012). Synthesis, characterization, and in vitro cytotoxicity of triorganotin 3,5-Di-tert-butyl-4-hydroxybenzoates. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 42(1), 82-87. http://dx.doi.org/10.1080/15533174.2011.609233. http://dx.doi.org/10.1080/15533174.2011....
). |
Alkaloids |
Reserpine |
Antibacterial (Negi et al., 2014Negi, J. S., Bisht, V., Bhandari, A. K., Bisht, D. S., Singh, P., & Singh, N. (2014). Quantification of reserpine content and antibacterial activity of Rauvolfia serpentina (L.) Benth. ex Kurz. African Journal of Microbiological Research, 8(2), 162-166. http://dx.doi.org/10.5897/AJMR2013.5847. http://dx.doi.org/10.5897/AJMR2013.5847...
). |
Trigonelline |
Hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities (Zhou et al., 2012Zhou, J., Chan, L., & Zhou, S. (2012). Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease. Current Medicinal Chemistry, 19(21), 3523-3531. http://dx.doi.org/10.2174/092986712801323171. PMid:22680628. http://dx.doi.org/10.2174/09298671280132...
). |
Nicotinamide |
As an adjunct in many dermatological diseases because of its antiinflammatory, antioxidant, barrier repair and protective effects (Bains et al., 2018Bains, P., Kaur, M., Kaur, J., & Sharma, S. (2018). Nicotinamide: mechanism of action and indications in dermatology. Indian Journal of Dermatology, Venereology and Leprology, 84(2), 234-237. http://dx.doi.org/10.4103/ijdvl.IJDVL_286_17. PMid:29405129. http://dx.doi.org/10.4103/ijdvl.IJDVL_28...
). |
4-Picoline |
Anticancer (Altay et al., 2018Altay, A., Caglar, S., Caglar, B., & Sahin, O. (2018). Synthesis, structural, thermal elucidation and in vitro anticancer activity of novel silver(I) complexes with non-steroidal anti-inflammatory drugs diclofenac and mefenamic acid including picoline derivatives. Polyhedron, 151, 160-170. http://dx.doi.org/10.1016/j.poly.2018.05.038. http://dx.doi.org/10.1016/j.poly.2018.05...
). |
Amino acid derivatives |
Choline |
Essential nutrient for human health (Zeisel & da Costa, 2009Zeisel, S. H., & da Costa, K. A. (2009). Choline: an essential nutrient for public health. Nutrition Reviews, 67(11), 615-623. http://dx.doi.org/10.1111/j.1753-4887.2009.00246.x. PMid:19906248. http://dx.doi.org/10.1111/j.1753-4887.20...
). |
Betaine |
Anti-inflammatory (Zhao et al., 2018Zhao, G., He, F., Wu, C., Li, P., Li, N., Deng, J., Zhu, G., Ren, W., & Peng, Y. (2018). Betaine in inflammation: Mechanistic aspects and applications. Frontiers in Immunology, 9, 1070. http://dx.doi.org/10.3389/fimmu.2018.01070. PMid:29881379. http://dx.doi.org/10.3389/fimmu.2018.010...
). |
Total
|
18 compounds |
|