Bacillus subtilis var natto |
Vegetable cheese, Natto, Japan |
Nattokinase |
Sumi et al. (1987)Sumi, H., Hamada, H., Tsushima, H., Mihara, H., & Muraki, H. (1987). A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet. Experientia, 43(10), 1110-1111. http://dx.doi.org/10.1007/BF01956052. PMid:3478223. http://dx.doi.org/10.1007/BF01956052...
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Bacillus natto, NK |
Natto, Japan |
Nattokinase |
Fujita et al. (1993)Fujita, M., Nomura, K., Hong, K., Ito, Y., Asada, A., & Nishimuro, S. (1993). Purification and characterization of a strong fibrinolytic enzyme (Nattokinase) in the vegetable cheese Natto, a popular soybean fermented food in Japan. Biochemical and Biophysical Research Communications, 197(3), 1340-1347. http://dx.doi.org/10.1006/bbrc.1993.2624. PMid:8280151. http://dx.doi.org/10.1006/bbrc.1993.2624...
|
Bacillus sp. |
Tofuyo, Japan |
SMCE |
Fujita et al. (1993)Fujita, M., Nomura, K., Hong, K., Ito, Y., Asada, A., & Nishimuro, S. (1993). Purification and characterization of a strong fibrinolytic enzyme (Nattokinase) in the vegetable cheese Natto, a popular soybean fermented food in Japan. Biochemical and Biophysical Research Communications, 197(3), 1340-1347. http://dx.doi.org/10.1006/bbrc.1993.2624. PMid:8280151. http://dx.doi.org/10.1006/bbrc.1993.2624...
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Katsuwonus pelamis
|
Skipjack, Japan |
Katsuwokinase |
Sumi et al. (1995)Sumi, H., Nakajima, N., & Yatagai, C. (1995). A unique strong fibrinolytic enzyme (datsuwokinase) in skipjack “Shiokara”, a Japanese traditional fermented food. Comparative Biochemistry and Physiology, 112(3), 543-547. http://dx.doi.org/10.1016/0305-0491(95)00100-X. PMid:8529030. http://dx.doi.org/10.1016/0305-0491(95)0...
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Bacillus sp. CK |
Chungkook-jang, Korea |
CK |
Kim et al. (1996aKim, W., Choi, K., Kim, Y., Park, H., Choi, J., Lee, Y., Oh, H., Kwon, I., & Lee, S. (1996a). Purification and characterization of a fibrinolytic enzyme produced from Bacillus sp. strain CK 11–4 screened from Chungkook-Jang. Applied and Environmental Microbiology, 62(7), 2482-2488. http://dx.doi.org/10.1128/AEM.62.7.2482-2488.1996. PMid:8779587. http://dx.doi.org/10.1128/AEM.62.7.2482-...
,bKim, W., Choi, K., Kim, Y., Park, H., Choi, J., Lee, Y., Oh, H., Kwon, I., & Lee, S. (1996b). Purification and characterization of a fibrinolytic enzyme produced from Bacillus sp. strain CK 11-4 screened from Chungkook-Jang. Applied and Environmental Microbiology, 62(7), 1488-2482. http://dx.doi.org/10.1128/AEM.62.7.2482-2488.1996. PMid:8779587. http://dx.doi.org/10.1128/AEM.62.7.2482-...
) |
Bacillus sp. KA38 |
Jeot-gal, Korea |
Jeot-gal enzyme |
Hyun-Kuk Kim et al. (1997)Hyun-Kuk Kim, Gu-Taek Kim, Dae-Kyung Kim, Won-A Choi, Sung-Hoon Park, Yong-Kee Jeong, & In-Soo Kong. (1997). Purification and characterization of a novel fibrinolytic enzyme from Bacillus sp. KA38 originated from fermented fish. Journal of Fermentation and Bioengineering, 84(4), 307-312. http://dx.doi.org/10.1016/S0922-338X(97)89249-5. http://dx.doi.org/10.1016/S0922-338X(97)...
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Bacillus sp. |
Kimchi, Korea |
Bacillus protease |
Noh et al. (1999)Noh, K. A., Kim, D. H., Choi, N. S., & Kim, S. H. (1999). Isolation of fibrinolytic enzyme producing strains from kimchi. Korean Journal of Food Science Technology, 31, 219-223.
|
Armillaria mella
|
Armillaria mella |
Neutral metalloprotease |
Kim & Kim (1999)Kim, J. H., & Kim, Y. S. (1999). A fibrinolytic metalloprotease from the fruiting bodies of an edible mushroom, Armillariella mellea. Bioscience, Biotechnology, and Biochemistry, 63(12), 2130-2136. http://dx.doi.org/10.1271/bbb.63.2130. PMid:10664846. http://dx.doi.org/10.1271/bbb.63.2130...
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Bacillus sp. DJ-4 |
Doen-jang, Korea |
Subtilisin DJ-4 |
Kim & Choi (2000)Kim, S. H., & Choi, N. S. (2000). Purification and characterization of subtilisin DJ-4 secreted by Bacillus sp strain DJ-4 screened from Doen-Jang. Bioscience, Biotechnology, and Biochemistry, 64(8), 1722-1725. http://dx.doi.org/10.1271/bbb.64.1722. PMid:10993162. http://dx.doi.org/10.1271/bbb.64.1722...
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Bacillus subtilis IMR-NK1 |
Natto, Japan |
Nattokinase |
Chang et al. (2000)Chang, C. T., Fan, M. H., Kuo, F. C., & Sung, H. Y. (2000). Potent fibrinolytic enzyme from a mutant of Bacillus subtilis IMR-NK1. Journal of Agricultural and Food Chemistry, 48(8), 3210-3216. http://dx.doi.org/10.1021/jf000020k. PMid:10956093. http://dx.doi.org/10.1021/jf000020k...
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Bacillus sp. KDO-13 |
Soybeanpaste, Korea |
- |
Lee et al. (2001)Lee, S. K., Bae, D. H., Kwon, T. J., Lee, S. B., Lee, H. H., Park, J. H., Heo, S., & Johnson, M. G. (2001). Purification and characterization of a fibrinolytic enzyme from Bacillus sp. KDO-13 isolated from soybean paste. Journal of Microbiology and Biotechnology, 11(5), 845-852.
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Enterococcus faecalis
|
Tempe, Indonesia |
E. faecalis BRCA-5 |
Joo et al. (2002)Joo, Y. S., Yu, M. E., Sim, G. S., Kwon, S. T., Hwang, J. K., Shin, J. K., Yeo, I. H., & Pyung, Y. R. (2002). Screening and characterization of microorganisms with fibrinolytic activity from fermented foods. Journal of Microbiology and Biotechnology, 12, 649-656.
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Bacillus subtilis
|
Natto, Japan |
Nattokinase |
Yamashita et al. (2003)Yamashita, T., Oda, E., Giddings, J. C., & Yamamoto, J. (2003). The Effect of dietary Bacillus natto productive protein on in vivo endogenous thrombolysis. Pathophysiology of Haemostasis and Thrombosis, 33(3), 138-143. http://dx.doi.org/10.1159/000077822. PMid:15170394. http://dx.doi.org/10.1159/000077822...
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B. amyloliquefaciens DC-4 |
Douchi, China |
Subtilisin DFE |
Peng et al. (2003)Peng, Y., Huang, Q., Zhang, R., & Zhang, Y. (2003). Purification and characterization of a fibrinolytic enzyme produced by Bacillus emyloliquefaciens DC-4 screened from douchi, a traditional Chinese soybean food. Journal of Biochemistry and Molecular Biology, 134(1), 45-52. http://dx.doi.org/10.1016/S1096-4959(02)00183-5. PMid:12524032. http://dx.doi.org/10.1016/S1096-4959(02)...
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Bacillus subtilis QK02 |
Fermented soybean |
QK-1 and QK-2 |
Ko et al. (2004)Ko, J. H., Yan, J. P., Zhu, L., & Qi, Y. P. (2004). Identification of two novel fibrinolytic enzymes from Bacillus subtilis QK02. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP, 137(1), 65-74. http://dx.doi.org/10.1016/j.cca.2003.11.008. PMid:14984705. http://dx.doi.org/10.1016/j.cca.2003.11....
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Bacillus firmus NA-1 |
Natto, Japan |
- |
Seo & Lee (2004)Seo, J. H., & Lee, S. P. (2004). Production of fibrinolytic enzyme from soybean grits fermented by Bacillus firmus NA-1. Journal of Medicinal Food, 7(4), 442-449. http://dx.doi.org/10.1089/jmf.2004.7.442. PMid:15671687. http://dx.doi.org/10.1089/jmf.2004.7.442...
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Bacillus sp. DJ-2 |
Doen-jang, Korea |
bpDJ-2 |
Choi et al., (2005)Choi, N. S., Yoo, K. H., Hahm, J. H., Yoon, K. S., Chang, K. T., Hyun, B. H., Maeng, P. J., & Kim, S. H. (2005). Purification and characterization of a new peptidase, bacillopeptidase DJ-2, having fibrinolytic activity: produced by Bacillus sp. DJ 2 from Doen-Jang. Journal of Microbiology and Biotechnology, 15(1), 72-79.
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Rhizopus chinensis 12 |
Chinese wine, China |
- |
Xiao-lan et al. (2005)Xiao-lan, L., Lian-Xiang, D., Fu-Ping, L., Xi-Qun, Z., & Jing, X. (2005). Purification and characterization of a novel fibrinolytic enzyme from Rhizopus chinensis 12. Applied Microbiology and Biotechnology, 67(2), 209-214. http://dx.doi.org/10.1007/s00253-004-1846-5. PMid:15614557. http://dx.doi.org/10.1007/s00253-004-184...
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Fusarium sp |
Tempe
|
- |
Sugimoto et al. (2007)Sugimoto, S., Fujii, T., Morimiya, T., Johdo, O., & Nakamura, T. (2007). The fibrinolytic activity of a novel protease derived from tempeh producing fungus, Fusarium sp. BLB. Bioscience, Biotechnology, and Biochemistry, 71(9), 2184-2189. http://dx.doi.org/10.1271/bbb.70153. PMid:17827689. http://dx.doi.org/10.1271/bbb.70153...
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B. amyloliquefaciens
|
Fermented chickpeas, China |
- |
Wei et al. (2011)Wei, X., Luo, M., Xu, L., Zhang, Y., Lin, X., Kong, P., & Liu, H. (2011). Production of fibrinolytic enzyme from Bacillus amyloliquefaciens by fermentation of chickpeas, with the evaluation of the anticoagulant and antioxidant properties of chickpeas. Journal of Agricultural and Food Chemistry, 59(8), 3957-3963. http://dx.doi.org/10.1021/jf1049535. PMid:21391672. http://dx.doi.org/10.1021/jf1049535...
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Bacillus coagulans
|
Fermented fish, Jambal roti and Terasi, Indonesia |
- |
Prihanto et al. (2013)Prihanto, A.A., Darius, & Firdaus, M. (2013). Proteolytic and fibrinolytic activities of halophilic lactic acid bacteria from two indonesian fermented foods. Journal of Microbiology, Biotechnology and Food Sciences, 2(5), 2291-2293.
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Bacillus licheniformis RO3 |
Red oncom, Indonesia |
- |
Afifah et al. (2014)Afifah, D.N., Sulchan, M., Syah, D., & Suhartono, M. T. (2014). Isolation and identification of fibrinolytic protease-producing microorganisms from Red Oncom and Gembus, Indonesian fermented soybean cakes. Malaysian Journal of Microbiology, 10(4), 273-279. http://dx.doi.org/10.21161/mjm.61914. http://dx.doi.org/10.21161/mjm.61914...
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Bacillus pumillus
|
Gembus, Indonesia |
- |
Afifah et al. (2014)Afifah, D.N., Sulchan, M., Syah, D., & Suhartono, M. T. (2014). Isolation and identification of fibrinolytic protease-producing microorganisms from Red Oncom and Gembus, Indonesian fermented soybean cakes. Malaysian Journal of Microbiology, 10(4), 273-279. http://dx.doi.org/10.21161/mjm.61914. http://dx.doi.org/10.21161/mjm.61914...
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Bacillus licheniformis
|
Soy flour
|
|
Gad et al. (2014)Gad, R. G., Nirmala, S., & Sivvaswamy, S. N. (2014). Fibrinolytic enzyme from Bacillus amyloliquefaciens: optimisation and scale up studies. International Journal of Pharmacy and Pharmaceutical Sciences, 6(10), 370-378.
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Bacillus amyloliquefaciens
|
Spoilt milk
|
- |
Gad et al. (2014)Gad, R. G., Nirmala, S., & Sivvaswamy, S. N. (2014). Fibrinolytic enzyme from Bacillus amyloliquefaciens: optimisation and scale up studies. International Journal of Pharmacy and Pharmaceutical Sciences, 6(10), 370-378.
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Bacillus subtilis ZA400 |
Kimchi, Korea |
BsfA |
Ahn et al. (2015)Ahn, M. J., Ku, H. J., Lee, S. H., & Lee, J. H. (2015). Characterization of a novel fibrinolytic enzyme, bsfa, from Bacillus subtilis ZA 400 in kimchi reveals its pertinence to thrombosis treatment. Journal of Microbiology and Biotechnology, 25(12), 2090-2099. http://dx.doi.org/10.4014/jmb.1509.09048. PMid:26403822. http://dx.doi.org/10.4014/jmb.1509.09048...
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Stenotrophomonas sp |
Oncom, Indonesia |
Stenoprotease |
Nailufar et al. (2016)Nailufar, F., Tjandrawinata, R. R., & Suhartono, M. T. (2016). Thrombus degradation by fibrinolytic enzyme of Stenotrophomonas sp. originated from Indonesian soybean-based fermented food on Wistar rats. Advances in Pharmacological Sciences, 1-9. http://dx.doi.org/10.1155/2016/4206908. https://doi.org/10.1155/2016/4206908...
, Kurnia et al. (2017)Kurnia, F., Tjandrawinata, R. R., Yulandi, A., & Suhartono, M. T. (2017). Protease of Stenotrophomonas sp. from Indonesian fermented food gene cloning and analysis. Journal of Biological Research (Thessaloniki), 90(2), 70-76.
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