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Vascular Cognitive Impairment (VCI) after non-embolic ischemic stroke during a 12-month follow-up in Brazil

COMPROMETIMENTO COGNITIVO VASCULAR (CCV) APÓS ACIDENTE VASCULAR ISQUÊMICO NÃO EMBÓLICO, EM SEGUIMENTO DE 12 MESES NO BRASIL

ABSTRACT

VCI represents a spectrum of cognitive impairments associated with stroke, vascular brain injury, or subclinical disease ranging from the least to most severe manifestations. Few studies are available on the prevalence of post-stroke VCI and none have been conducted in Brazil.

Objective:

To determine the prevalence rates of VCI and associated risk factors in a sample of ischemic stroke patients.

Methods:

We evaluated 172 patients with ischemic stroke for cognitive impairment one year after ictus.

Results:

Patients comprised 81 women (47.1%) and had a mean age of 67.77 (7.86) years, schooling of 3.52 (2.99) years, and MMSE score of 24.94 (3.59) points. After cognitive evaluation, 4.6% were diagnosed as CIND (cognitive impairment no dementia) and 12.2% had a diagnosis of dementia (probable vascular dementia in 20 patients and one subject with cerebrovascular disease and Alzheimer's disease).

Conclusion:

The prevalence of dementia was lower than previous reports but our sample had a lower age than others, while a 12 month-period of follow-up prevented interference from associated neurodegenerative disorders.

Key words:
vascular cognitive impairment; cognitive impairment no dementia; vascular dementia; post-stroke dementia; post-stroke cognitive impairment

Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento R. Vergueiro, 1353 sl.1404 - Ed. Top Towers Offices, Torre Norte, São Paulo, SP, Brazil, CEP 04101-000, Tel.: +55 11 5084-9463 | +55 11 5083-3876 - São Paulo - SP - Brazil
E-mail: revistadementia@abneuro.org.br | demneuropsy@uol.com.br