Qualidade de vida em pessoas com comprometimento cognitivo leve: uma revisão sistemática e metanálise

Gopalakrishnan, Priya; Tiwari, Shivani; Nagaraja, Ravishankar; Krishnan, Gopee

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Dementia & Neuropsychologia

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Brasil

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Sumário

View & Review • Dement. neuropsychol. 18 • 2024 • https://doi.org/10.1590/1980-5764-DN-2023-0093 copiar

Qualidade de vida em pessoas com comprometimento cognitivo leve: uma revisão sistemática e metanálise

Autoria SCIMAGO INSTITUTIONS RANKINGS

RESUMO

O aumento global da população idosa tem suscitado preocupações quanto a condições relacionadas à idade, como demência e comprometimento cognitivo leve (CCL), e seus impactos nas pessoas afetadas. Indivíduos com CCL apresentam déficits cognitivos superiores ao esperado para sua idade e nível de alfabetização, e embora a condição seja considerada leve estudos demonstram que até déficits mais sutis podem afetar a qualidade de vida (QdV).

Objetivo:

Este trabalho explora e compara a QdV em idosos com e sem CCL, por meio de revisão sistemática e metanálise.

Métodos:

Após uma busca detalhada de artigos até maio de 2021 em relevantes bases eletrônicas (PubMed Central, PubMed, Scopus, CINAHL Plus, Web of Science, ProQuest e Cochrane) usando as palavras-chave "mild cognitive impairment", "quality of life", "old", "old aged", "aged", "older adult", "geriatrics", "healthy controls", "healthy participants", e "normal controls", incluímos 23 artigos na revisão e 12 na metanálise.

Resultados:

A qualidade dos artigos foi avaliada com a ferramenta Modified Downs and Black. A revisão revelou diferenças nas pontuações de QdV entre idosos com CCL e saudáveis, mas a metanálise revelou diferenças estatisticamente não significativas, sugerindo uma QdV ligeiramente inferior nos primeiros.

Conclusão:

Futuras pesquisas devem enfocar ferramentas de avaliação de QdV específicas para idosos com CCL e em estudos de acompanhamento para melhor compreensão do perfil cognitivo em evolução e da qualidade de vida desses indivíduos.

Palavras-chave:
Qualidade de Vida; Disfunção Cognitiva; Idoso; Revisão Sistemática; Metanálise

Reference	Year	Age (years)	Sample size	Study design	Tools for assessing MCI	Tools for assessing QOL	Outcome measures
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Stites et al.¹⁸18 Stites SD, Harkins K, Rubright JD, Karlawish J. Relationships between cognitive complaints and quality of life in older adults with mild cognitive impairment, Mild Alzheimer's Disease Dementia, and normal cognition. Alzheimer Dis Assoc Disord. 2018;32(4):276-83. https://doi.org/10.1097/WAD.0000000000000262 https://doi.org/10.1097/WAD.000000000000...	2018	≥ 65 HC 79.2±7.1 MCI 78.1±6.4	HC= 99 MCI=92	Recruited from longitudinal cohort study	NACC and Petersen criteria MMSE	EQ-5D EQ-VAS QOL-AD DEMQOL	QOL
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QOL Measure	Domains	Score
SF-36	physical functioning, role limitations due to physical health, pain, general health, energy/fatigue, social functioning, role limitations due to emotional problems, emotional well-being	0–100
EQ-5D	mobility, self-care, usual activities, pain/discomfort, anxiety/depression	Index value +1 to −1
WHOQOL-BREF	physical health, psychological state, social relationships, environmental context	5-point Likert scale
DQOL	positive affect, negative affect, feelings of belonging, self-esteem, sense of aesthetics	5-point Likert scale
QOL-AD	physical health, energy, mood, living situation, memory, family, marriage or close relationship, friends, self as a whole, ability to do chores around the house, ability to do things for fun, money, life as a whole	4-point Likert scale
ADRQL	social Interaction, awareness of self, feelings and mood, enjoyment of activities, response to surroundings	0–100%
SDL	physical health, mental health, self-care, gait, housework, house facilities, partner and family relationship, hobby and leisure activities, social interaction, economic state and social security, job satisfaction	5-point Likert scale
LASA	physical well-being, emotional state, faith, religious involvement, intellectual state, social interactions, pain frequency, pain intensity, coping ability	10-point Likert scale
HRQOL	Single-item overall quality-of-life rating	5-point Likert scale
WHOQOL- OLD	sensory abilities; autonomy; past, present, and future activities; social participation; fears related to death and dying; and intimacy	0–100
DEMQOL	Degree of difficulty in daily life related to health, well-being, cognitive functioning, social relationships, daily activities, and self-concept	0–100
CUBRECAVI	health (subjective, objective and psychic); social integration; functional abilities; activity and leisure time; quality of environment; satisfaction with life; education; income; health and social services	5-point Likert scale
SF12	Physical Function, Physical Role, Body Pain, General Health, Vitality, Social Function, Emotional Role, and Mental Health	0–100

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E-mail: revistadementia@abneuro.org.br | demneuropsy@uol.com.br

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[1] Correspondence:
Gopee Krishnan; Email: brain.language.krishnan@gmail.com.