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Retest effects in a diverse sample: sociodemographic predictors and possible correction approaches

EFEITO DE RETESTE EM UMA AMOSTRA DIVERSA: PREDITORES SOCIODEMOGRÁFICOS E POSSÍVEIS ABORDAGENS PARA A CORREÇÃO

ABSTRACT.

Repeated cognitive assessment in longitudinal studies favors the occurrence of retest effects, usually increasing the scores obtained at the follow-up assessments when compared to baseline. Therefore, retest effects can compromise the evaluation of cognitive decline in older adults.

Objectives:

We aimed to verify the occurrence of the retest effect and the impact of sociodemographic characteristics on the follow-up scores in a sample of 5,592 participants with a diverse sociodemographic profile, who were assessed twice during 4 years of follow-up.

Methods:

We tested two possible approaches to correct the retest effect and calculated the Reliable Change Index.

Results:

We observed increased scores at the follow-up assessment after 4 years, but the results indicate a modest occurrence of retest effects. The regression difference correction successfully generated follow-up corrected scores, while the mean difference did not provide effective corrections. Sociodemographic characteristics had a minor impact on the retest.

Conclusions:

We recommend the regression difference correction for retest effects. The absence of this methodological approach might lead to biased results using longitudinal cognitive scores.

Keywords:
Reproducibility of Results; Aged; Longitudinal Studies; Psychometrics

Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento R. Vergueiro, 1353 sl.1404 - Ed. Top Towers Offices, Torre Norte, São Paulo, SP, Brazil, CEP 04101-000, Tel.: +55 11 5084-9463 | +55 11 5083-3876 - São Paulo - SP - Brazil
E-mail: revistadementia@abneuro.org.br | demneuropsy@uol.com.br