ABSTRACT
This article provides a review of immunity, diagnosis, and clinical aspects of rotavirus disease. It also informs about the changes in epidemiology of diarrheal disease and genetic diversity of circulating group A rotavirus strains following the introduction of vaccines. Group A rotavirus is the major pathogen causing gastroenteritis in animals. Its segmented RNA genome can lead to the emergence of new or unusual strains in human populations via interspecies transmission and/or reassortment events.
Gastroenteritis/epidemiology; Diarrhea; Vaccination; Genotyping techniques
VP: viral protein; NSP: non-structural protein.Source: Mossel E, Estes M, Ramig F. Coding assignments and virion locations of rotavirus proteins and 3D structure of the rotavirus particle [Internet]. [cited 2015 Nov 23]. Available from: http://www.reoviridae.org/dsrna_virus_proteins/rotavirus%20figure.htm(10)