miR-18a |
S |
Up-regulated |
Prognostic |
Fish et al. (2020Fish EJ, Martinez-Romero EG, DeInnocentes P, Koehler JW, Prasad N, Smith AN and Bird RC (2020) Circulating microRNA as biomarkers of canine mammary carcinoma in dogs. J Vet Intern Med 34:1282-1290.) |
miR-19b |
S |
Up-regulated |
Diagnostic |
Fish et al. (2020Fish EJ, Martinez-Romero EG, DeInnocentes P, Koehler JW, Prasad N, Smith AN and Bird RC (2020) Circulating microRNA as biomarkers of canine mammary carcinoma in dogs. J Vet Intern Med 34:1282-1290.) |
miR-21 |
T/S |
Up-regulated |
Diagnostic and prognostic |
Boggs et al. (2008Boggs RM, Wright ZM, Stickney MJ, Porter WW and Murphy KE (2008) MicroRNA expression in canine mammary cancer. Mamm Genome 19:561-569.); von Deetzen et al. (2014von Deetzen M-C, Schmeck BT, Gruber AD and Klopfleisch R (2014) Malignancy associated MicroRNA expression changes in canine mammary cancer of different malignancies. ISRN Vet Sci 2014:148597.); Bulkowska et al. (2017Bulkowska M, Rybicka A, Senses KM, Ulewicz K, Witt K, Szymanska J, Taciak B, Klopfleisch R, Hellmén E, Dolka I et al. (2017) MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours. BMC Cancer 17:728.); Jain et al. (2021Jain M, Ingole SD, Deshmukh RS, Bharucha SV, Nagvekar AS, Gaikwad RV and Kharde SD (2021) CEA, CA 15-3, and miRNA expression as potential biomarkers in canine mammary tumors. Chromosom Res 29:175-188.); Ramadan et al. (2021Ramadan ES, Salem NY, Emam IA, AbdElKader NA, Farghali HA and Khattab MS (2021) MicroRNA-21 expression, serum tumor markers, and immunohistochemistry in canine mammary tumors. Vet Res Commun 46:377-388.) |
miR-29b |
T/S |
Down-regulated |
Diagnostic and prognostic |
Bulkowska et al. (2017Bulkowska M, Rybicka A, Senses KM, Ulewicz K, Witt K, Szymanska J, Taciak B, Klopfleisch R, Hellmén E, Dolka I et al. (2017) MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours. BMC Cancer 17:728.); Jain et al. (2021Jain M, Ingole SD, Deshmukh RS, Bharucha SV, Nagvekar AS, Gaikwad RV and Kharde SD (2021) CEA, CA 15-3, and miRNA expression as potential biomarkers in canine mammary tumors. Chromosom Res 29:175-188.) |
|
T/S |
Up-regulated |
Diagnostic |
Boggs et al. (2008Boggs RM, Wright ZM, Stickney MJ, Porter WW and Murphy KE (2008) MicroRNA expression in canine mammary cancer. Mamm Genome 19:561-569.); Fish et al. (2020Fish EJ, Martinez-Romero EG, DeInnocentes P, Koehler JW, Prasad N, Smith AN and Bird RC (2020) Circulating microRNA as biomarkers of canine mammary carcinoma in dogs. J Vet Intern Med 34:1282-1290.) |
miR-96 |
T/S |
Up-regulated |
Diagnostic |
Jeong et al. (2019Jeong S-J, Lee K-H, Nam A-R and Cho J-Y (2019) Genome-wide methylation profiling in canine mammary tumor reveals miRNA candidates associated with human breast cancer. Cancers (Basel) 11:1466.) |
miR-101 |
T/S |
Down-regulated |
Diagnostic |
von Deetzen et al. (2014von Deetzen M-C, Schmeck BT, Gruber AD and Klopfleisch R (2014) Malignancy associated MicroRNA expression changes in canine mammary cancer of different malignancies. ISRN Vet Sci 2014:148597.); Bulkowska et al. (2017Bulkowska M, Rybicka A, Senses KM, Ulewicz K, Witt K, Szymanska J, Taciak B, Klopfleisch R, Hellmén E, Dolka I et al. (2017) MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours. BMC Cancer 17:728.) |
miR-125a |
T/S |
Down-regulated |
Prognostic |
von Deetzen et al. (2014von Deetzen M-C, Schmeck BT, Gruber AD and Klopfleisch R (2014) Malignancy associated MicroRNA expression changes in canine mammary cancer of different malignancies. ISRN Vet Sci 2014:148597.); Bulkowska et al. (2017Bulkowska M, Rybicka A, Senses KM, Ulewicz K, Witt K, Szymanska J, Taciak B, Klopfleisch R, Hellmén E, Dolka I et al. (2017) MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours. BMC Cancer 17:728.) |
|
S |
Up-regulated |
Diagnostic |
Fish et al. (2020Fish EJ, Martinez-Romero EG, DeInnocentes P, Koehler JW, Prasad N, Smith AN and Bird RC (2020) Circulating microRNA as biomarkers of canine mammary carcinoma in dogs. J Vet Intern Med 34:1282-1290.) |
miR-126 |
P |
Up-regulated |
Diagnostic |
Heishima et al. (2017Heishima K, Ichikawa Y, Yoshida K, Iwasaki R, Sakai H, Nakagawa T, Tanaka Y, Hoshino Y, Okamura Y, Murakami M et al. (2017) Circulating microRNA-214 and -126 as potential biomarkers for canine neoplastic disease. Sci Rep7:2301.) |
miR-143 |
T/S |
Down-regulated |
Prognostic |
von Deetzen et al. (2014von Deetzen M-C, Schmeck BT, Gruber AD and Klopfleisch R (2014) Malignancy associated MicroRNA expression changes in canine mammary cancer of different malignancies. ISRN Vet Sci 2014:148597.); Bulkowska et al. (2017Bulkowska M, Rybicka A, Senses KM, Ulewicz K, Witt K, Szymanska J, Taciak B, Klopfleisch R, Hellmén E, Dolka I et al. (2017) MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours. BMC Cancer 17:728.) |
miR-145 |
T/S |
Down-regulated |
Prognostic |
von Deetzen et al. (2014von Deetzen M-C, Schmeck BT, Gruber AD and Klopfleisch R (2014) Malignancy associated MicroRNA expression changes in canine mammary cancer of different malignancies. ISRN Vet Sci 2014:148597.); Bulkowska et al. (2017Bulkowska M, Rybicka A, Senses KM, Ulewicz K, Witt K, Szymanska J, Taciak B, Klopfleisch R, Hellmén E, Dolka I et al. (2017) MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours. BMC Cancer 17:728.) |
miR-149 |
T/S |
Down-regulated |
Diagnostic |
Jeong et al. (2019Jeong S-J, Lee K-H, Nam A-R and Cho J-Y (2019) Genome-wide methylation profiling in canine mammary tumor reveals miRNA candidates associated with human breast cancer. Cancers (Basel) 11:1466.) |
miR-194 |
T |
Up-regulated |
Diagnostic |
von Deetzen et al. (2014von Deetzen M-C, Schmeck BT, Gruber AD and Klopfleisch R (2014) Malignancy associated MicroRNA expression changes in canine mammary cancer of different malignancies. ISRN Vet Sci 2014:148597.) |
miR-195 |
T/CL |
Down-regulated |
Diagnostic |
Zhang et al. (2021) |
miR-210 |
T/S |
Down-regulated |
Diagnostic |
von Deetzen et al. (2014von Deetzen M-C, Schmeck BT, Gruber AD and Klopfleisch R (2014) Malignancy associated MicroRNA expression changes in canine mammary cancer of different malignancies. ISRN Vet Sci 2014:148597.); Bulkowska et al. (2017Bulkowska M, Rybicka A, Senses KM, Ulewicz K, Witt K, Szymanska J, Taciak B, Klopfleisch R, Hellmén E, Dolka I et al. (2017) MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours. BMC Cancer 17:728.) |
miR-214 |
P |
Up-regulated |
Diagnostic |
Heishima et al. (2017Heishima K, Ichikawa Y, Yoshida K, Iwasaki R, Sakai H, Nakagawa T, Tanaka Y, Hoshino Y, Okamura Y, Murakami M et al. (2017) Circulating microRNA-214 and -126 as potential biomarkers for canine neoplastic disease. Sci Rep7:2301.) |
miR-497 |
T/CL |
Down-regulated |
Diagnostic |
Zhang et al. (2021) |
miR-8832 |
T/S |
Up-regulated |
Diagnostic |
Jeong et al. (2019Jeong S-J, Lee K-H, Nam A-R and Cho J-Y (2019) Genome-wide methylation profiling in canine mammary tumor reveals miRNA candidates associated with human breast cancer. Cancers (Basel) 11:1466.) |