Chen et al 2001 |
16-year-old Chinese Female |
MFH |
2 × 2.5cm |
Enlarging painless swelling |
5 days |
None |
Hemiglossectomy with modified radial neck dissection |
Negative margins and nodes |
Free of disease at 3 years |
Geist et al 1990 |
60-year-old Caucasian Male |
MFH in thorax, metastasis to tongue |
1.5 × 0.5cm |
Progressive weakness and fatigue with painful enlarging mass in tongue |
2 months of weakness and fatigue, 1–2 weeks of tongue mass |
None |
Doxorubicin hydrochloride and DTIC chemotherapy followed by surgical resection with adjuvant radiation for lung persistence and chemo with fludarabine for metastasis |
Disease continued to spread |
Died of disease 16 months after presentation |
Lin et al 1994 |
57-year-old Taiwanese Male |
MFH |
− |
Painful mass |
1 month |
2.5 years ago |
Total glossectomy and partial mandibulectomy followed by subtotal excision with palliative chemotherapy for recurrence |
Recurred 6 months after primary surgery |
Died at 26mo |
Lopez et al 2011 |
8-year-old Caucasian Female |
BFH |
0.4 × 0.4cm |
Asymptomatic nodule noticed by parents |
6 months |
None |
Excision |
Clearance |
No recurrence at 3 years follow-up |
Mahajan et al 1989 |
28-year-old German Female |
MFH |
− |
Pain and trismus progressing to hoarseness and decreased tongue mobility |
7 months |
None |
Neoadjuvant chemo, modified neck dissection, partial mandibulectomy, partial glossectomy, and pharyngectomy with adjuvant radiotherapy and chemotherapy |
Clearance with negative lymph nodes |
No recurrence at 15 months |
Manni et al 1986 |
61-year-old Caucasian Male |
MFH |
9 × 5 × 3cm |
Progressive tongue swelling, bleeding, and swallowing difficulties |
6 months |
None |
Hemiglossectomy with supraomohyoid neck dissection |
|
No recurrence at 2 years |
McMillan et al 1986 |
42-year-old Female |
MFH |
2.5cm |
Enlarging symptomless swelling |
8 weeks |
None |
Excisional biopsy followed by left hemiglossectomy after histologic diagnosis |
|
No recurrence at 9 months |
Pandey et al 2013 |
26-year-old Indian Male |
BFH |
6 × 5cm |
Slow growing mass |
5 months |
None |
Excision and blunt dissection |
|
Disease-free at 1 month f/u |
Priya et al 2013 |
30-year-old Indian Female |
BFH |
3 × 3cm |
Nodular mass causing speech difficulty |
7 months |
None |
Excision under local anesthesia |
Tongue function improvement |
No recurrence at 3 years |
Rapidis et al 2005 |
24-year-old Caucasian Male |
MFH |
3 × 2 × 1cm |
Slowly enlarging painless swelling |
5 months |
None |
Surgical resection with 1 cm tumor-free margins |
|
Disease-free at 18 months |
Restrepo et al 1987 |
5-month-old Caucasian Male |
MFH |
− |
Difficulty bottle feeding |
− |
None |
Partial glossectomy with adjuvant iridium implants and 2 years of actinomycin D, vincristine sulfate, cyclophosphamide chemo |
Unremarkable metastatic workup |
Disease free at 18 months after diagnosis (7 months after therapy completion) |
Velez et al 1986 |
14-year-old African American Female |
Atypical FH |
3.2 × 2 × 0.7cm |
Rapidly growing non-tender mass |
2 weeks |
None |
Excised with CO2 laser under general anesthesia followed by hemiglossectomy after recurrence |
Local recurrence within several weeks. Tumor-free margins on hemiglossectomy |
Patient died 6 months later due to Cystic Fibrosis |
Takimoto et al 1990 |
51-year-old Japanese Female |
FH |
2 × 1.5 × 1cm |
Sore throat with globus sensation |
“several months” |
None |
Elliptical excision with 5 mm margins |
|
Asymptomatic with no evidence of recurrence at 12 years |
Young et al 1989 |
67-year-old Taiwanese Female |
MFH |
− |
Rapidly growing protruding mass |
− |
5 years ago |
Tumor debulking by CO2 laser followed by excision with tongue flap push back reconstruction and adjuvant radiation for recurrence |
|
No evidence of recurrence at 3 years after excision |
Young et al 1989 |
52-year-old Taiwanese Male |
MFH |
− |
Globus sensation |
− |
12 years ago |
Tumor debulking by CO2 laser |
Neck metastasis found 1 month after debulking |
Died of disease 16 months after diagnosis |
Zapater et al 1995 |
71-year-old Caucasian Male |
MFH |
4 × 2cm |
Painful gum mass |
3 months |
None |
Telecobaltotherapy of the tongue and oral cavity and then curietherapy on the primary lesion |
No evidence of tumor macroscopically |
Recurrence at 8 months, patient died of disease one month later |
Bras et al 1987 |
72-year-old Caucasian Male |
MFH |
− |
Painless swelling |
3 months |
− |
Radium implants initially followed by local surgery and modified radical neck dissection for recurrence |
Partial response, recurrence |
Died of disease after 12 months |
Bras et al 1987 |
65-year-old Caucasian Male |
MFH |
− |
Found on follow-up from prior irradiation for SCC of the tongue |
− |
10 years ago |
Initial resection followed by surgery for local recurrence and radiotherapy + CYVADIC chemo for lung metastasis |
|
Died of disease after 20 months |
Barnes et al 1988 |
21-year-old Female |
MFH |
3cm |
Asymptomatic mass |
12 months |
None |
Partial right glossectomy with right modified radical neck dissection |
Negative lymph nodes |
No evidence of disease at 37 months |
Hiasa et al 1986 |
63-year-old Japanese Female |
Right pleural MFH metastasis to the tongue and other organs |
5 × 4 × 3cm |
Swelling of the right edge of the tongue |
− |
1 year ago |
Partial resection with adjuvant radiation to primary tumor. Followed by radiation to metastases |
|
Died of disease at 34 months |