Lockwood et al1616 Lockwood AH, Salvi RJ, Coad ML, Towsley ML,Wack DS,Murphy BW. The functional neuroanatomy of tinnitus: evidence for limbic system links and neural plasticity. Neurology 1998;50(1):114-120
|
4/6 |
PET |
Orofacial movements |
Temporal gyrus/hippocampus |
Giraud et al1818 Giraud AL, Chéry-Croze S, Fischer G, et al. A selective imaging of tinnitus. Neuroreport 1999;10(1):1-5
|
4 |
PET |
Eye movements |
Associated areas/auditory/temporal-parietal |
Mirz et al2424 Mirz F, Pedersen B, Ishizu K, et al. Positron emission tomography of cortical centers of tinnitus. Hear Res 1999;134(1-2): 133-144
|
12 |
PET |
Lidocaine/suppression |
Right temporal-front gyrus |
Andersson et al4141 Andersson G, Lyttkens L, Hirvelä C, Furmark T, Tillfors M, Fredrikson M. Regional cerebral blood flow during tinnitus: a PET case study with lidocaine and auditory stimulation. Acta Otolaryngol 2000;120(8):967-972
|
1 |
PET |
Lidocaine/suppression |
Left temporal lobe |
Mirz et al4141 Andersson G, Lyttkens L, Hirvelä C, Furmark T, Tillfors M, Fredrikson M. Regional cerebral blood flow during tinnitus: a PET case study with lidocaine and auditory stimulation. Acta Otolaryngol 2000;120(8):967-972
|
8 |
PET |
Sound/lidocaine |
Amygdala |
Muhlau et al2222 Mühlau M, Rauschecker JP, Oestreicher E, et al. Structural brain changes in tinnitus. Cereb Cortex 2006;16(9):1283-1288
|
28/28 |
fMRI |
Sound |
Nucleus acumbens/thalamic /reticular nucleus (↓volume) |
Plewnia et al3636 Plewnia C, Reimold M, Najib A, et al. Dose-dependent attenuation of auditory phantom perception (tinnitus) by PET-guided repetitive transcranial magnetic stimulation. Hum Brain Mapp 2007; 28(3):238-246
|
9 |
PET |
Lidocaine/rest |
Postcingulum, temp-par cortex |
Melcher et al1414 Melcher JR, Levine RA, Bergevin C, Norris B. The auditorymidbrain of people with tinnitus: abnormal sound-evoked activity revisited. Hear Res 2009;257(1-2):63-74
|
|
fMRI |
Sound |
Inferior colliculus |
Van Gendt et al4242 van Gendt MJ, Boyen K, de Kleine E, Langers DR, van Dijk P. The relation between perception and brain activity in gaze-evoked tinnitus. J Neurosci 2012;32(49):17528-17539
|
18/9 |
fMRI |
Gaze evoked/sound |
↑ IC and CN ; ↓AC /medial genicular body |
Rauschecker et al2626 Leaver AM, Seydell-Greenwald A, Turesky TK, Morgan S, Kim HJ, Rauschecker JP. Cortico-limbic morphology separates tinnitus from tinnitus distress. Front Syst Neurosci 2012;6:21
|
23/21 |
fMRI |
Sound |
↓Gray matter vmPFC/nucleus accumbens; ↑ gyrification dmPFC |
Husain et al2020 Husain FT, Pajor NM, Smith JF, et al. Discrimination task reveals differences in neural bases of tinnitus and hearing impairment. PLoS ONE 2011;6(10):e26639
|
8/7/11 |
fMRI |
Sound |
↓Front/parietal lobes |
Schecklmann et al2727 Schecklmann M, Landgrebe M, Poeppl TB, et al. Neural correlates of tinnitus duration and distress: a positron emission tomography study. Hum Brain Mapp 2013;34(1):233-240
|
91 |
PET |
Rest |
Left Heschl gyrus |