1 |
Al-Ansari et al., (2222 Al-Ansari A, Al-Naimi A, Alobaidy A, Assadiq K, Azmi MD, Shokeir AA. Efficacy of tamsulosin in the management of lower ureteral stones: a randomized double-blindplacebo- controlled study of 100 patients. Urology. 2010;75:4-7.), 2010, Qatar |
Tamsulosin 0.4mg |
Placebo |
4 weeks |
37.1(9.4) |
36.1 (9.3) |
32/18 |
35/15 |
Yes |
5.8 (2.4) |
6 (2.5) |
2 |
Aldemir et al., (2323 Aldemir M, Uçgül YE, Kayıgil O. Evaluation of the efficiency of tamsulosin and Rowatinex in patients with distal ureteral stones: a prospective, randomized, controlled study. Int Urol Nephrol. 2011; 43:79-83.), 2011, Turkey |
Group I- Tamsulosin 0.4mg |
Diclofenac 100 mg |
10 days |
42.4 (16) |
43.5 (16.6) |
22/9 |
19/10 |
Yes |
6.7 (1.4) |
6.6 (1.7) |
|
|
Group II- Rowatinex 100 mg thrice daily |
|
|
46.5 (16.5) |
|
17/13 |
|
|
6.8 (2) |
|
3 |
Alizadeh et al., (2424 Alizadeh M, Magsudi M. The effect of tamsulosin in the medical treatment of distal ureteral stones. Glob J Health Sci. 2014; 6:44-8.), 2014, Iran |
Tamsulosin 0.4 mg |
Placebo |
4 weeks |
- |
- |
29/21 |
32/14 |
3-6 mm |
- |
- |
4 |
Bajwa et al., (2525 Bajwa MSA, Rahim J, Rahim J, Saeed Q, Hussain K, Ashraf S, et al. Efficacy of Tamsulosin for Clearance of Lower Ureteric Stones. PJMHS. 2013;7:769-72.), 2013, Pakistan |
Tamsulosin 0.4 mg |
Diclofenac 50 mg |
4 weeks |
32.4 (8.3) |
33.8 (9.6) |
18/12 |
19/11 |
Yes |
6.9 (1.4) |
6.6 (1.4) |
5 |
Cervenakov et al., (2626 Cervenàkov I, Fillo J, Mardiak J, Kopecný M, Smirala J, Lepies P. Speedy elimination of ureterolithiasis in lower part of ureters with the alpha 1-blocker--Tamsulosin. Int Urol Nephrol. 2002; 34:25-9.), 2002, Slovakia |
Tamsulosin 0.4 mg |
Tramadol 50 mg / Diazepan and Veral 50 |
- |
- |
|
32/19 |
33/18 |
Yes |
- |
- |
6 |
El-Gamal et al., (2727 El-Gamal O, El-Bendary M, Ragab M, Rasheed M. Role of combined use of potassium citrate and tamsulosin in the management of uric acid distal ureteral calculi. Urol Res. 2012; 40:219-24.), 2011, Egypt |
Group II Tamsulosin 0.4mg |
Group I Placebo control Group III UralytU |
4 weeks |
35.3(5.7) |
36.2 (6) |
32/16 |
34/12 |
Yes |
7.9 (1.9) |
7.7 (1.6) |
|
|
Group IV Uralyt-U plus tamsulosin |
|
|
|
|
|
|
|
|
|
7 |
ElGalaly et al., (2828 Elgalaly H, Eliwa A, Seleem M, Salem E, Omran M, Shello H, et al. Silodosin in the treatment of distal ureteric stones in children: A prospective, randomised, placebo-controlled study. Arab J Urol. 2017; 15:194-8.), 2017, Egypt |
Group I Tamsulosin 0.4 mg |
- |
4 weeks |
35.5 (11) |
- |
32/19 |
- |
Yes |
5.6( 1.2) |
- |
|
|
Group II Silodosin 8mg |
|
|
33.6 (9.9) |
|
35/17 |
|
|
5.4(1.5) |
|
8 |
Vincendeau et al., (2929 Vincendeau S, Bellissant E, Houlgatte A, Doré B, Bruyère F, Renault A, et al. Tamsulosin hydrochloride vs placebo for management of distal ureteral stones: a multicentric, randomized, double-blind trial. Arch Intern Med. 2010; 170:2021-7.), 2010, France |
Tamsulosin 0.4 mg |
Placebo |
6 weeks |
38.9 (12) |
39 (11) |
43/18 |
52/9 |
2-7 mm |
2.9 (1) |
3.2 (1.2) |
9 |
Yilmaz et al., (3030 Yilmaz E, Batislam E, Basar MM, Tuglu D, Ferhat M, Basar H. The comparison and efficacy of 3 different alpha1-adrenergic blockers for distal ureteral stones. J Urol. 2005; 173:2010-2.), 2005, Turkey |
Group II Tamsulosin 0.4mg Group III |
Group I No treatment |
4 weeks |
40.6(10) |
41.6(12) |
9/20 |
19/9 |
Yes |
6(1.2) |
6(1.4) |
|
|
Terazosin 5mg Group IV Doxazosin 4mg |
|
|
|
|
|
|
|
|
|
10 |
Aggarwal et al., (3131 Agrawal M, Gupta M, Gupta A, Agrawal A, Sarkari A, Lavania P. Prospective randomized trial comparing efficacy of alfuzosin and tamsulosin in management of lower ureteral stones. Urology. 2009; 73:706-9.), 2009, India |
I – Tamsulosin |
III -Placebo |
4 weeks |
(31.4) |
(35.3) |
26/8 |
24/10 |
Yes |
6.17 |
6.35 |
|
|
II – Alfuzosin |
|
|
(38.7) |
|
28/6 |
|
|
6.7 |
|
11 |
Ahmad et al., (3232 Ahmad H, Azim W, Akmal M, Murtaza B, Mahmood A, Nadim A, et al. Medical expulsive treatment of distal ureteral stone using tamsulosin. J Ayub Med Coll Abbottabad. 2015; 27:48-50.), 2015, Pakistan |
I -Tamsulosin |
II- Placebo |
4 weeks |
- |
- |
4-10mm |
|
<8mm |
5.78mm |
- |
12 |
Cha et al., (3333 Cha WH, Choi JD, Kim KH, Seo YJ, Lee K. Comparison and efficacy of low-dose and standard- dose tamsulosin and alfuzosin in medical expulsive therapy for lower ureteral calculi: prospective, randomized, comparative study. Korean J Urol. 2012; 53:349-54.), 2012, Korea |
ITamsulosin - 0.2mg OD |
- |
4 weeks |
(45.07) |
- |
31/10 |
- |
4-10mm |
5.49 |
- |
|
|
II Tamsulosin - 0.2 mg BD |
|
|
|
|
|
|
|
|
|
|
|
III Alfuzosin |
|
|
|
|
|
|
|
|
|
|
|
IV Trospium |
|
|
|
|
|
|
|
|
|
13 |
Dell’Atti et al., (3434 Dell’Atti L. Silodosin versus tamsulosin as medical expulsive therapy for distal ureteral stones: a prospective randomized study. Urologia. 2015; 82:54-7.), 2015, Italy |
I Tamsulosin |
- |
3 weeks |
(35) |
- |
39/27 |
|
4-10mm |
5.37 |
- |
|
|
II - Silodosin |
|
|
|
|
|
|
|
|
|
14 |
Furyk et al., (3535 Furyk JS, Chu K, Banks C, Greenslade J, Keijzers G, Thom O, et al. Distal Ureteric Stones and Tamsulosin: A Double-Blind, Placebo-Controlled, Randomized, Multicenter Trial. Ann Emerg Med. 2016; 67:86-95.e2.), 2016, Australia |
I -Tamsulosin |
II-Placebo |
4 weeks |
> 18 |
>18 |
156/42 |
164/31 |
Yes |
4 |
3.7 |
15 |
Ochoa-Gomez et al., (3636 Ochoa-Gómez R, Prieto-Díaz-Chávez E, Trujillo-Hernández B, Vásquez C. Tamsulosin does not have greater efficacy than conventional treatment for distal ureteral stone expulsion in Mexican patients. Urol Res. 2011; 39:491-5.), 2011, Mexico |
I- Tamsulosin |
II-Placebo |
4 weeks |
(38.5) |
(38.2) |
15/17 |
21/12 |
5-10mm |
5.3 |
5.2 |
16 |
Hermanns et al., (3737 Hermanns T, Sauermann P, Rufibach K, Frauenfelder T, Sulser T, Strebel RT. Is there a role for tamsulosin in the treatment of distal ureteral stones of 7 mm or less? Results of a randomised, double-blind, placebo-controlled trial. Eur Urol. 2009; 56:407-12.), 2009, Switzerland |
I-Tamsulosin |
II-Placebo |
3 weeks |
(36) |
(41) |
39/6 |
36/9 |
7mm or less |
4.1 |
3.8 |
17 |
Itoh et al., (3838 Itoh Y, Okada A, Yasui T, Ando R, Tozawa K, Sasaki S, et al. Administration of the selective alpha 1A-adrenoceptor antagonist silodosin facilitates expulsion of size 5-10 mm distalureteral stones, as compared to control. Int Urol Nephrol. 2013; 45:675-8.), 2013, Japan |
II- Silodosin |
I -Placebo |
4 weeks |
(56.3) |
(55.8) |
All male |
- |
Yes |
4.87 |
5.07 |
18 |
Kumar et al., (1212 Kumar S, Jayant K, Agrawal MM, Singh SK, Agrawal S, Parmar KM. Role of tamsulosin, tadalafil, and silodosin as the medical expulsive therapy in lower ureteric stone: a randomized trial (a pilot study). Urology. 2015; 85:59-63.), 2015, India |
I - Tamsulosin |
- |
4 weeks |
(36.4) |
- |
62/28 |
- |
5-10mm |
7.44 |
- |
|
|
II - Silodosin |
|
|
|
|
|
|
|
|
|
|
|
III - Tadalafil |
|
|
|
|
|
|
|
|
|
19 |
Sameer et al., (3939 Sameer, Lal S, Charak KS, Chakravarti S, Kohli S, Ahmad S. Efficacy of nifedipine and alfuzosin in the management of distal ureteric stones: A randomized, controlled study. Indian J Urol. 2014; 30:387-91.), 2014, India |
I-Nifedipine II- Alfuzosin |
III- Control |
4 weeks |
(32.74) |
(33.06) |
19/16 |
23/12 |
Yes |
6.5 |
6.37 |
20 |
Ahmad et al., (4040 Ahmed AF, Al-Sayed AY. Tamsulosin versus Alfuzosin in the Treatment of Patients with Distal Ureteral Stones: Prospective, Randomized, Comparative Study. Korean J Urol. 2010; 51:193-7.), 2010, Saudi Arabia |
I = Tamsulosin 0.4mg |
III- control- Diclofenac 75mg |
30 days |
40.7(14.8) |
38.9(13.3) |
9/10 |
19/09 |
Yes |
4.97 (2.24) |
5.39 (1.81) |
|
|
II - Alfuzosin 10mg |
|
|
|
|
|
|
|
|
|
21 |
Elsaid et al., (4141 El Said NO, El Wakeel L, Kamal KM, Morad Ael R. Alfuzosin treatment improves the rate and time for stone expulsion in patients with distal uretral stones: a prospective randomized controlled study. Pharmacotherapy. 2015; 35:470-6.), 2015, Egypt |
Alfuzosin 5mg BD |
control - Diclofenac + Hydration |
4 weeks |
32.8(9.5) |
32.1(9.2) |
18/10 |
16/10 |
Yes |
6.3 (2.1) |
5.9 (1.9) |
22 |
Nuraj et al., (4242 Nuraj P, Hyseni N. The Role of the Tamsulosin in the Medical Expulsion Therapy for Distal Ureteral Stones. Med Arch. 2017; 71:137-40.), 2017, Kosovo |
I-Tamsulosin 0.4mg |
Control- Diclofenac |
4 weeks |
35.5(11.0) |
35.4(10.8) |
34/18 |
35/17 |
4-10mm |
6.5 (1.6) |
6.6 (1.5) |
23 |
Pedro et al., (4343 Pedro RN, Hinck B, Hendlin K, Feia K, Canales BK, Monga M. Alfuzosin stone expulsion therapy for distal ureteral calculi: a double-blind, placebo controlled study. J Urol. 2008; 179:2244-7.), 2008, USA |
I- Alfuzosin |
Placebo |
4 weeks |
36.69(13.6) |
42.03(12.8) |
28/6 |
27/8 |
Up to 8mm |
3.83 (0.94) |
4.07 (1.13) |
24 |
Pickard et al., (4444 Pickard R, Starr K, MacLennan G, Lam T, Thomas R, Burr J, et al. Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial. Lancet. 2015; 386:341-9.), 2015, UK |
I - Tamsulosin 0.4mg |
III- Placebo |
4 weeks |
43.1(11.5) |
48.2(12.3) |
315/68 |
299/85 |
Yes |
4.6(1.6) |
4.5(1.7) |
|
|
III - Nifedipine 30 mg |
|
|
|
|
|
|
|
|
|
25 |
Rahman et al., (4545 Rahman MJ, Faridi MS, Mibang N, Singh RS. Comparing tamsulosin, silodosin versus silodosin plus tadalafil as medical expulsive therapy for lower ureteric stones: A randomised trial. Arab J Urol. 2017; 16:245-9.), 2018, India |
I - Tamsulosin 0.4mg OD |
- |
4 weeks |
38(10) |
- |
24/16 |
- |
5-10mm |
7.5(1.20) |
|
|
|
II - Silodosin 8 mg OD |
|
|
|
|
|
|
|
|
|
|
|
III- Silodosin 8mg + Tadalafil 5 mg |
|
|
|
|
|
|
|
|
|
26 |
Sur et al., (4646 Sur RL, Shore N, L’Esperance J, Knudsen B, Gupta M, Olsen S, et al. Silodosin to facilitate passage of ureteral stones: a multi-institutional, randomized, double-blinded, placebo-controlled trial. Eur Urol. 2015; 67:959-64.), 2015, USA |
I- Silodosin 8mg OD |
II- Placebo |
4 weeks |
47 (13) |
47 (15) |
72/53 |
80/37 |
4-10mm |
5.4 (1.4) |
5.5 (1.6) |
27 |
Wang et al., (4747 Wang CJ, Huang SW, Chang CH. Efficacy of an alpha1 blocker in expulsive therapy of lower ureteral stones. J Endourol. 2008; 22:41-6.), 2008, Taiwan |
I- Tamsulosin 0.4 mg OD |
III- control |
2 weeks |
50.4(9.7) |
50.9(9.6) |
22/10 |
23/08 |
Yes |
6.5(1.3) |
6.5(1.4) |
|
|
II- Terazosin 2 mg OD |
|
|
|
|
|
|
|
|
|
28 |
Ye et al., (4949 Zhangqun Ye, Guohua Zeng, Huan Yang, et al. Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial. Eur Urol 2018;73:385-91.), 2018, Wuhan, China |
I- Tamsulosin 0.4mg |
II- Placebo |
4 weeks |
40.1(11.6) |
40.7(12.3) |
556/1086 |
605/1049 |
Yes |
5.8(1.9) |
5.7(1.8) |
29 |
De Sio et al., (5050 De Sio M, Autorino R, Di Lorenzo G, Damiano R, Giordano D, Cosentino L, et al. Medical expulsive treatment of distal-ureteral stones using tamsulosin: a single-center experience. J Endourol. 2006; 20:12-6.), 2006, Italy |
Diclofenac 100mg/day + Aescin 80mg/day |
- |
2 weeks |
44.5(11.3) |
- |
26/20 |
- |
Yes |
6.4(1.3) |
- |
|
|
Diclofenac 100mg + Aescin 80mg + Tamsulosin 0.4 mg |
|
|
|
|
|
|
|
|
|
30 |
Wang et al., (4848 Wang CJ, Tsai PC, Chang CH. Efficacy of Silodosin in Expulsive Therapy for Distal Ureteral Stones: A Randomized Double-blinded Controlled Trial. Urol J. 2016; 13:2666-71.), 2016, Taiwan |
I- Silodosin 8mg |
II- control |
2 weeks |
51.4(8.6) |
51.5(10.5) |
40/22 |
43/18 |
Yes |
6.4(1.4) |
6.4(1.3) |
31 |
Yuksel et al., (5151 Yuksel M, Yilmaz S, Tokgoz H, Yalcinkaya S, Baş S, Ipekci T, et al. Efficacy of silodosin in the treatment of distal ureteral stones 4 to 10 mm in diameter. Int J Clin Exp Med. 2015;8:19086-92.), 2015, Turkey |
Group II Silodosin 4 mg/day |
Group I Placebo |
3 weeks |
35.31 (11.55) |
35.23 (11.2) |
19/16 |
20/15 |
4-10mm |
6.40(1.61) |
6.34(1.57) |