BMI
|
|
|
P value |
I2 score |
|
Overweight (1212. Handel LN, Shetty R, Sigman M. The relationship between varicoceles and obesity. J Urol. 2006;176:2138-40; discussion 2140.
13. May M, Taymoorian K, Beutner S, Helke C, Braun KP, Lein M, et al. Body size and weight as predisposing factors in varicocele. Scand J Urol Nephrol. 2006;40:45-8.
14. Nielsen ME, Zderic S, Freedland SJ, Jarow JP. Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index. Urology. 2006;68:392-6.
15. Prabakaran S, Kumanov P, Tomova A, Hubaveshki S, Agarwal A. Adolescent varicocele: association with somatometric parameters. Urol Int. 2006;77:114-7.
16. Chen SS, Huang WJ. Differences in biochemical markers and body mass index between patients with and without varicocele. J Chin Med Assoc. 2010;73:194-8.
17. Oster J. Varicocele in children and adolescents. An investigation of the incidence among Danish school children. Scand J Urol Nephrol. 1971;5:27-32.
18. Shafi H, Agajani Delavar M. Differences in body mass index and height factors between men with and without varicocele. Med Glas (Zenica). 2015;12:212-5.
19. Walter SD, Cook RJ. A comparison of several point estimators of the odds ratio in a single 2 × 2 contingency table. Biometrics. 1991;47:795-811.
20. Wei M, Macera CA, Davis DR, Hornung CA, Nankin HR, Blair SN. Total cholesterol and high density lipoprotein cholesterol as important predictors of erectile dysfunction. Am J Epidemiol. 1994;140:930-7.
21. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60.-2222. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.) |
11 |
0.70 (0.56-0.86) |
0.000 |
92.4% |
|
Obese (1212. Handel LN, Shetty R, Sigman M. The relationship between varicoceles and obesity. J Urol. 2006;176:2138-40; discussion 2140.,1313. May M, Taymoorian K, Beutner S, Helke C, Braun KP, Lein M, et al. Body size and weight as predisposing factors in varicocele. Scand J Urol Nephrol. 2006;40:45-8.,1515. Prabakaran S, Kumanov P, Tomova A, Hubaveshki S, Agarwal A. Adolescent varicocele: association with somatometric parameters. Urol Int. 2006;77:114-7.
16. Chen SS, Huang WJ. Differences in biochemical markers and body mass index between patients with and without varicocele. J Chin Med Assoc. 2010;73:194-8.
17. Oster J. Varicocele in children and adolescents. An investigation of the incidence among Danish school children. Scand J Urol Nephrol. 1971;5:27-32.
18. Shafi H, Agajani Delavar M. Differences in body mass index and height factors between men with and without varicocele. Med Glas (Zenica). 2015;12:212-5.
19. Walter SD, Cook RJ. A comparison of several point estimators of the odds ratio in a single 2 × 2 contingency table. Biometrics. 1991;47:795-811.
20. Wei M, Macera CA, Davis DR, Hornung CA, Nankin HR, Blair SN. Total cholesterol and high density lipoprotein cholesterol as important predictors of erectile dysfunction. Am J Epidemiol. 1994;140:930-7.
21. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60.-2222. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.) |
10 |
0.46 (0.37-0.58) |
0.000 |
80.3% |
|
Underweight (1414. Nielsen ME, Zderic S, Freedland SJ, Jarow JP. Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index. Urology. 2006;68:392-6.,1717. Oster J. Varicocele in children and adolescents. An investigation of the incidence among Danish school children. Scand J Urol Nephrol. 1971;5:27-32.,1818. Shafi H, Agajani Delavar M. Differences in body mass index and height factors between men with and without varicocele. Med Glas (Zenica). 2015;12:212-5.,2222. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.) |
4 |
1.31 (1.04-1.64) |
0.001 |
81.3% |
Study design (Overweight)
|
|
|
|
|
|
Case-control study (1212. Handel LN, Shetty R, Sigman M. The relationship between varicoceles and obesity. J Urol. 2006;176:2138-40; discussion 2140.,1313. May M, Taymoorian K, Beutner S, Helke C, Braun KP, Lein M, et al. Body size and weight as predisposing factors in varicocele. Scand J Urol Nephrol. 2006;40:45-8.,1515. Prabakaran S, Kumanov P, Tomova A, Hubaveshki S, Agarwal A. Adolescent varicocele: association with somatometric parameters. Urol Int. 2006;77:114-7.
16. Chen SS, Huang WJ. Differences in biochemical markers and body mass index between patients with and without varicocele. J Chin Med Assoc. 2010;73:194-8.-1717. Oster J. Varicocele in children and adolescents. An investigation of the incidence among Danish school children. Scand J Urol Nephrol. 1971;5:27-32.,1919. Walter SD, Cook RJ. A comparison of several point estimators of the odds ratio in a single 2 × 2 contingency table. Biometrics. 1991;47:795-811.
20. Wei M, Macera CA, Davis DR, Hornung CA, Nankin HR, Blair SN. Total cholesterol and high density lipoprotein cholesterol as important predictors of erectile dysfunction. Am J Epidemiol. 1994;140:930-7.-2121. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60.) |
8 |
0.76 (0.69-0.84) |
0.523 |
0.0% |
|
Cross-sectional study (1414. Nielsen ME, Zderic S, Freedland SJ, Jarow JP. Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index. Urology. 2006;68:392-6.,1818. Shafi H, Agajani Delavar M. Differences in body mass index and height factors between men with and without varicocele. Med Glas (Zenica). 2015;12:212-5.,2222. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.) |
3 |
0.58 (0.37-0.93) |
0.000 |
97.5% |
Geographic (Overweight)
|
|
|
|
|
|
America (1212. Handel LN, Shetty R, Sigman M. The relationship between varicoceles and obesity. J Urol. 2006;176:2138-40; discussion 2140.,1313. May M, Taymoorian K, Beutner S, Helke C, Braun KP, Lein M, et al. Body size and weight as predisposing factors in varicocele. Scand J Urol Nephrol. 2006;40:45-8.,1515. Prabakaran S, Kumanov P, Tomova A, Hubaveshki S, Agarwal A. Adolescent varicocele: association with somatometric parameters. Urol Int. 2006;77:114-7.) |
3 |
0.79 (0.70-0.90) |
0.185 |
40.7% |
|
Europe (1616. Chen SS, Huang WJ. Differences in biochemical markers and body mass index between patients with and without varicocele. J Chin Med Assoc. 2010;73:194-8.
17. Oster J. Varicocele in children and adolescents. An investigation of the incidence among Danish school children. Scand J Urol Nephrol. 1971;5:27-32.
18. Shafi H, Agajani Delavar M. Differences in body mass index and height factors between men with and without varicocele. Med Glas (Zenica). 2015;12:212-5.-1919. Walter SD, Cook RJ. A comparison of several point estimators of the odds ratio in a single 2 × 2 contingency table. Biometrics. 1991;47:795-811.) |
4 |
0.65 (0.50-0.85) |
0.000 |
84.3% |
|
Asia (1414. Nielsen ME, Zderic S, Freedland SJ, Jarow JP. Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index. Urology. 2006;68:392-6.,2121. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60.,2222. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.) |
3 |
0.67 (0.44-1.03) |
0.024 |
73.3% |
|
Africa (2020. Wei M, Macera CA, Davis DR, Hornung CA, Nankin HR, Blair SN. Total cholesterol and high density lipoprotein cholesterol as important predictors of erectile dysfunction. Am J Epidemiol. 1994;140:930-7.) |
1 |
0.375 (0.125-1.128) |
/ |
/ |
Sensitivity analysis omitting Rais et al. study
|
|
|
|
|
|
Overweight (1212. Handel LN, Shetty R, Sigman M. The relationship between varicoceles and obesity. J Urol. 2006;176:2138-40; discussion 2140.
13. May M, Taymoorian K, Beutner S, Helke C, Braun KP, Lein M, et al. Body size and weight as predisposing factors in varicocele. Scand J Urol Nephrol. 2006;40:45-8.
14. Nielsen ME, Zderic S, Freedland SJ, Jarow JP. Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index. Urology. 2006;68:392-6.
15. Prabakaran S, Kumanov P, Tomova A, Hubaveshki S, Agarwal A. Adolescent varicocele: association with somatometric parameters. Urol Int. 2006;77:114-7.
16. Chen SS, Huang WJ. Differences in biochemical markers and body mass index between patients with and without varicocele. J Chin Med Assoc. 2010;73:194-8.-1717. Oster J. Varicocele in children and adolescents. An investigation of the incidence among Danish school children. Scand J Urol Nephrol. 1971;5:27-32.,1919. Walter SD, Cook RJ. A comparison of several point estimators of the odds ratio in a single 2 × 2 contingency table. Biometrics. 1991;47:795-811.
20. Wei M, Macera CA, Davis DR, Hornung CA, Nankin HR, Blair SN. Total cholesterol and high density lipoprotein cholesterol as important predictors of erectile dysfunction. Am J Epidemiol. 1994;140:930-7.
21. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60.-2222. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.) |
10 |
0.77 (0.69-0.86) |
0.082 |
41.4% |