1 |
t(1;2) |
1p22;2q31 |
2 miscarriages |
Dong et al., 2014 (3131. Dong Y, Li LL, Wang RX, Yu XW, Yun X, Liu RZ. Reproductive outcomes in recurrent pregnancy loss associated with a parental carrier of chromosome abnormalities or polymorphisms. Genet Mol Res. 2014;13:2849-56.) |
2 |
t(1;2) |
1q21;2p23 |
Oligozoospermia |
The present study |
3 |
t(1;2) |
1q21;2q37 |
Oligozoospermia |
The present study |
4 |
t(1;2) |
1q21;2q37 |
Oligozoospermia |
Li et al., 2012 (2323. Li D, Zhang H, Wang R, Zhu H, Li L, Liu R. Chromosomal abnormalities in men with pregestational and gestational infertility in northeast China. J Assist Reprod Genet. 2012;29:829-36.) |
5 |
t(1;2) |
1q32;2q36 |
Abortion |
Templado et al., 1990 (3232. Templado C, Navarro J, Requena R, Benet J, Ballesta F, Egozcue J. Meiotic and sperm chromosome studies in a reciprocal translocation t(1;2)(q32;q36). Hum Genet. 1990;84:159-62.) |
6 |
t(1;2) |
1q32.1;2q11.2 |
Oligozoospermia |
Vozdova et al., 2013 (99. Vozdova M, Oracova E, Kasikova K, Prinosilova P, Rybar R, Horinova V, et al. Balanced chromosomal translocations in men: relationships among semen parameters, chromatin integrity, sperm meiotic segregation and aneuploidy. J Assist Reprod Genet. 2013;30:391-405.) |
7 |
t(1;2) |
1q42;2q37 |
2 fetal malformations |
Zhang et al., 2006 (3333. Zhang YP, Xu JZ, Yin M, Chen MF, Ren DL. [Pregnancy outcomes of 194 couples with balanced translocations]. Zhonghua Fu Chan Ke Za Zhi. 2006;41:592-6.) |
8 |
t(1;2) |
1q42;2q33 |
Miscarriage |
Stasiewicz-Jarocka et al., 2000 (3434. Stasiewicz-Jarocka B, Raczkiewicz B, Kowalczyk D, Zawada M, Midro AT. Genetic risk of families with t(1;2)(q42;q33) GTG, RHG, QFQ, FISH. Ginekol Pol. 2000;71:1262-72. Erratum in: Ginekol Pol 2001;72:54.) |
9 |
t(2;3) |
2p13;3q27 |
Recurrent pregnancy loss |
Ocak et al., 2013 (3535. Ocak Z, Özlü T, Ozyurt O. Association of recurrent pregnancy loss with chromosomal abnormalities and hereditary thrombophilias. Afr Health Sci. 2013;13:447-52.) |
10 |
t(2;3) |
2q21; 3p21 |
Recurrent spontaneous abortion |
Tunç et al., 2016 (2626. Tunç E, Tanrıverdi N, Demirhan O, Süleymanova D, Çetinel N. Chromosomal analyses of 1510 couples who have experienced recurrent spontaneous abortions. Reprod Biomed Online. 2016;32:414-9.) |
11 |
t(2;3) |
2q24;3p26) |
Normal semen |
Martin, 1994 (3636. Martin RH. Sperm chromosome complements in a man heterozygous for a reciprocal translocation t(2;3)(q24;p26). Hum Reprod. 1994;9:1512-5.) |
12 |
t(2;4) |
2p21;4p14 |
Recurrent abortion |
Portnoï et al., 1988 (3737. Portnoï MF, Joye N, van den Akker J, Morlier G, Taillemite JL. Karyotypes of 1142 couples with recurrent abortion. Obstet Gynecol. 1988;72:31-4.) |
13 |
t(2;4) |
2q31;4q31 |
Stillbirth |
Li et al., 2012 (2323. Li D, Zhang H, Wang R, Zhu H, Li L, Liu R. Chromosomal abnormalities in men with pregestational and gestational infertility in northeast China. J Assist Reprod Genet. 2012;29:829-36.) |
14 |
t(2;4) |
2q31;4q31 |
2 stillbirths |
Dong et al., 2014 (3131. Dong Y, Li LL, Wang RX, Yu XW, Yun X, Liu RZ. Reproductive outcomes in recurrent pregnancy loss associated with a parental carrier of chromosome abnormalities or polymorphisms. Genet Mol Res. 2014;13:2849-56.) |
15 |
t(2;5) |
2p21;5p15 |
Recurrent spontaneous abortion |
Gada Saxena et al., 2012 (2525. Gada Saxena S, Desai K, Shewale L, Ranjan P, Saranath D. Chromosomal aberrations in 2000 couples of Indian ethnicity with reproductive failure. Reprod Biomed Online. 2012;25:209-18.) |
16 |
t(2;5) |
2p13;5p15 |
Recurrent fetal wastage |
Fryns et al., 1998 (3838. Fryns JP, Van Buggenhout G. Structural chromosome rearrangements in couples with recurrent fetal wastage. Eur J Obstet Gynecol Reprod Biol. 1998;81:171-6.) |
17 |
t(2;5) |
2p11;5q15 |
Abortion |
Templado et al., 1988 (3939. Templado C, Navarro J, Benet J, Genescà A, Pérez MM, Egozcue J. Human sperm chromosome studies in a reciprocal translocation t(2;5). Hum Genet. 1988;79:24-8.) |
18 |
t(2;5) |
2p11;5q31 |
Recurrent abortion |
Portnoï et al., 1988 (3737. Portnoï MF, Joye N, van den Akker J, Morlier G, Taillemite JL. Karyotypes of 1142 couples with recurrent abortion. Obstet Gynecol. 1988;72:31-4.) |
19 |
t(2;5) |
2q12;5q35.3 |
Spontaneous miscarriage |
Kochhar et al., 2013 (4040. Kochhar PK, Ghosh P. Reproductive outcome of couples with recurrent miscarriage and balanced chromosomal abnormalities. J Obstet Gynaecol Res. 2013;39:113-20.) |
20 |
t(2;6) |
2p13;6p21.3 |
Recurrent abortion |
Al-Hussain et al., 2000 (4141. Al-Hussain M, Al-Nuaim L, Abu Talib Z, Zaki OK. Cytogenetic study in cases with recurrent abortion in Saudi Arabia. Ann Saudi Med. 2000;20:233-6.) |
21 |
t(2;6) |
2p12;6q24 |
Two earlier miscarriages |
Lim et al., 2003 (4242. Lim AS, Lim TH, Kee SK, Chieng R, Tay SK. Sperm segregation patterns by fluorescence in situ hybridization studies of a 46,XY,t(2;6) heterozygote giving rise to a rare triploid product of conception with a 69,XXY,t(2;6)(p12;q24) der(6)t(2;6)(p12;q24)pat karyotype. Am J Med Genet A. 2003;117A:172-6.) |
22 |
t(2;6) |
2q21;6p21 |
3 first-trimester abortions |
The present study |
23 |
t(2;6) |
2q34;6p24 |
Recurrent spontaneous abortion |
Gada Saxena et al., 2012 (2525. Gada Saxena S, Desai K, Shewale L, Ranjan P, Saranath D. Chromosomal aberrations in 2000 couples of Indian ethnicity with reproductive failure. Reprod Biomed Online. 2012;25:209-18.) |
24 |
t(2;7) |
2p23;7p22 |
Recurrent fetal wastage |
Fryns et al., 1998 (3838. Fryns JP, Van Buggenhout G. Structural chromosome rearrangements in couples with recurrent fetal wastage. Eur J Obstet Gynecol Reprod Biol. 1998;81:171-6.) |
25 |
t(2;7) |
2p13;7q34 |
Normal semen, IVF/PGD ET, twins 46,XX |
Vozdova et al., 2013 (99. Vozdova M, Oracova E, Kasikova K, Prinosilova P, Rybar R, Horinova V, et al. Balanced chromosomal translocations in men: relationships among semen parameters, chromatin integrity, sperm meiotic segregation and aneuploidy. J Assist Reprod Genet. 2013;30:391-405.) |
26 |
t(2;7) |
2p13;7q32 |
Primary infertility, abnormal semen |
Vozdova et al., 2013 (99. Vozdova M, Oracova E, Kasikova K, Prinosilova P, Rybar R, Horinova V, et al. Balanced chromosomal translocations in men: relationships among semen parameters, chromatin integrity, sperm meiotic segregation and aneuploidy. J Assist Reprod Genet. 2013;30:391-405.) |
27 |
t(2;7) |
2q31;7q34 |
Abnormal semen |
Vozdova et al., 2013 (99. Vozdova M, Oracova E, Kasikova K, Prinosilova P, Rybar R, Horinova V, et al. Balanced chromosomal translocations in men: relationships among semen parameters, chromatin integrity, sperm meiotic segregation and aneuploidy. J Assist Reprod Genet. 2013;30:391-405.) |
28 |
t(2;7) |
2p11.2;7q22.1 |
2 miscarriages |
Wiland et al., 2008 (33. Wiland E, Hobel CJ, Hill D, Kurpisz M. Successful pregnancy after preimplantation genetic diagnosis for carrier of t(2;7) (p11.2;q22) with high rates of unbalanced sperm and embryos: a case report. Prenat Diagn. 2008;28:36-41.) |
29 |
t(2;7) |
2q37.3;7q34) |
3 miscarriages |
Ahn et al., 2003 (4343. Ahn JM, Koo DH, Kwon KW, Lee YK, Lee YH, Lee HH, et al. Partial trisomy 2q(2q37.3->qter) and monosomy 7q(7q34->qter) due to paternal reciprocal translocation 2;7: a case report. J Korean Med Sci. 2003;18:112-3.) |
30 |
t(2;8) |
2p13;8q13 |
Multiple spontaneous abortions |
Castle et al., 1988 (4444. Castle D, Bernstein R. Cytogenetic analysis of 688 couples experiencing multiple spontaneous abortions. Am J Med Genet. 1988;29:549-56.) |
31 |
t(2;8) |
2p22;8p23.1 |
Spontaneous abortions |
Kyu Lim et al., 2004 (4545. Kyu Lim C, Hyun Jun J, Mi Min D, Lee HS, Young Kim J, Koong MK, et al. Efficacy and clinical outcome of preimplantation genetic diagnosis using FISH for couples of reciprocal and Robertsonian translocations: the Korean experience. Prenat Diagn. 2004;24:556-61.) |
32 |
t(2;8) |
2q35;8q11.2 |
Spontaneous abortions |
Kyu Lim et al., 2004 (4545. Kyu Lim C, Hyun Jun J, Mi Min D, Lee HS, Young Kim J, Koong MK, et al. Efficacy and clinical outcome of preimplantation genetic diagnosis using FISH for couples of reciprocal and Robertsonian translocations: the Korean experience. Prenat Diagn. 2004;24:556-61.) |
33 |
t(2;8) |
2q37;8q22 |
3 abortions |
Campana et al., 1986 (4646. Campana M, Serra A, Neri G. Role of chromosome aberrations in recurrent abortion: a study of 269 balanced translocations. Am J Med Genet. 1986;24:341-56.) |
34 |
t(2;9) |
2q21;9p22 |
Abortion |
Martin et al., 1990 (4747. Martin RH, Barclay L, Hildebrand K, Ko E, Fowlow SB. Cytogenetic analysis of 400 sperm from three translocation heterozygotes. Hum Genet. 1990;86:33-9.) |
35 |
t(2;9) |
2q37.3;9q12 |
Normal semen, increased risk of miscarriage |
Dul et al., 2012 (4848. Dul EC, van Echten-Arends J, Groen H, Dijkhuizen T, Land JA, van Ravenswaaij-Arts CM. Chromosomal abnormalities in azoospermic and non-azoospermic infertile men: numbers needed to be screened to prevent adverse pregnancy outcomes. Hum Reprod. 2012;27:2850-6.) |
36 |
t(2;10) |
2q33;10q24 |
Produced a child, 46,XX |
Faed et al., 1982 (4949. Faed MJ, Lamont MA, Baxby K. Cytogenetic and histological studies of testicular biopsies from subfertile men with chromosome anomaly. J Med Genet. 1982;19:49-56.) |
37 |
t(2;11) |
2p14;11q21 |
Repeated abortion |
Ananthapur et al., 2014 (55. Ananthapur V, Avvari S, Veena K, Sujatha M, Jyothy A. Non-Robertsonian translocation t (2;11) is associated with infertility in an oligospermic man. Andrologia. 2014;46:453-5.) |
38 |
t(2;11) |
2q24;11q32 |
Recurrent abortion |
Al-Hussain et al., 2000 (4141. Al-Hussain M, Al-Nuaim L, Abu Talib Z, Zaki OK. Cytogenetic study in cases with recurrent abortion in Saudi Arabia. Ann Saudi Med. 2000;20:233-6.) |
39 |
t(2;11) |
2q33;11q23 |
Produced a child, 46,XX |
The present study |
40 |
t(2;11) |
2q35;11q13 |
Produced a child, 46,XX,t(2;11) |
The present study |
41 |
t(2;12) |
2q31;12q24 |
3 first-trimester abortions |
Niroumanesh et al., 2011 (5050. Niroumanesh S, Mehdipour P, Farajpour A, Darvish S. A cytogenetic study of couples with repeated spontaneous abortions. Ann Saudi Med. 2011;31:77-9.) |
42 |
t(2;13) |
2q35;13q32 |
Repeated miscarriage |
Goddijn et al., 2004 (5151. Goddijn M, Joosten JH, Knegt AC, van derVeen F, Franssen MT, Bonsel GJ, Let al. Clinical relevance of diagnosing structural chromosome abnormalities in couples with repeated miscarriage. Hum Reprod. 2004;19:1013-7.) |
43 |
t(2;13) |
2q10;13q10 |
Oligozoospermia |
The present study |
44 |
t(2; 14) |
2p23.1;14q31 |
Abortion |
Rousseaux et al., 1995 (5252. Rousseaux S, Chevret E, Monteil M, Cozzi J, Pelletier R, Devillard F, et al. Meiotic segregation in males heterozygote for reciprocal translocations: analysis of sperm nuclei by two and three colour fluorescence in situ hybridization. Cytogenet Cell Genet. 1995;71:240-6.) |
45 |
t(2;14) |
2q12;14q32.33 |
Recurrent spontaneous abortion |
Manvelyan et al., 2007 (2727. Manvelyan M, Schreyer I, Höls-Herpertz I, Köhler S, Niemann R, Hehr U, et al. Forty-eight new cases with infertility due to balanced chromosomal rearrangements: detailed molecular cytogenetic analysis of the 90 involved breakpoints. Int J Mol Med. 2007;19:855-64.) |
46 |
t(2;14) |
2q31;14q24 |
2 stillbirths |
The present study |
47 |
t(2;14) |
2q37.1;14q31.2 |
Fetal malformations |
de la Fuente et al., 1988 (5353. de la Fuente AA, Gerssen-Schoorl KB, Breed AS. Partial duplication 14q/deletion 2q in two sibs due to t(2;14) (q37.1;q31.2) pat. Ann Genet. 1988;31:254-7.) |
48 |
t(2;15) |
2p11.2;15q15 |
Infertility |
The present study |
49 |
t(2;15) |
2q21;15p12 |
Recurrent fetal wastage |
Fryns et al., 1998 (3838. Fryns JP, Van Buggenhout G. Structural chromosome rearrangements in couples with recurrent fetal wastage. Eur J Obstet Gynecol Reprod Biol. 1998;81:171-6.) |
50 |
t(2;16) |
2p23;16q13 |
Recurrent spontaneous abortion |
The present study |
51 |
t(2;17) |
2q35;17p13 |
Abortion |
Jenderny, 1992 (5454. Jenderny J. Sperm chromosome analysis of two males heterozygous for a t(2;17)(q35;p13) and t(3;8)(p13;p21) reciprocal translocation. Hum Genet. 1992;90:171-3.) |
52 |
t(2;17) |
2q37.2; 17q25 |
Recurrent spontaneous abortion |
Bruyere et al., 2003 (5555. Bruyere H, Rajcan-Separovic E, Doyle J, Pantzar T, Langlois S. Familial cryptic translocation (2;17) ascertained through recurrent spontaneous abortions. Am J Med Genet A. 2003;123A:285-9.) |
53 |
t(2;18) |
2p21;18q11.2 |
5 miscarriages |
Estop et al., 1995 (5656. Estop AM, Van Kirk V, Cieply K. Segregation analysis of four translocations, t(2;18), t(3;15), t(5;7), and t(10;12), by sperm chromosome studies and a review of the literature. Cytogenet Cell Genet. 1995;70:80-7.) |
54 |
t(2;20) |
2p16;20p12 |
Recurrent abortion |
Sachs et al., 1985 (5757. Sachs ES, Jahoda MG, Van Hemel JO, Hoogeboom AJ, Sandkuyl LA. Chromosome studies of 500 couples with two or more abortions. Obstet Gynecol. 1985;65:375-8.) |
55 |
t(2;20) |
2p24.1;20q13.1 |
Recurrent abortion |
Trappe et al., 2002 (5858. Trappe R, Böhm D, Kohlhase J, Weise A, Liehr T, Essers G, et al. A novel family-specific translocation t(2;20) (p24.1;q13.1) associated with recurrent abortions: molecular characterization and segregation analysis in male meiosis. Cytogenet Genome Res. 2002;98:1-8.) |