Metalloproteases |
BmooFIBMP-I 37
|
P-I; 22.8 kDa; non-hemorrhagic; α-fibrinogenase |
-- |
Procoagulant in vitro |
-- |
BmooMP-I 41
|
P-I; 25 kDa; hemorrhagic; α-fibrinogenase |
-- |
Coagulation alteration |
-- |
BmooMPα-I 38
|
P-I; 24.5 kDa; non-hemorrhagic; α-fibrinogenase |
-- |
Anticoagulant in vivo |
Fibrinolytic |
BmooMPα-II 39
|
PI; 22.5 kDa; non-hemorrhagic; α-fibrinogenase |
Inhibition of aggregation |
Fibrinogenolytic Not pro/anticoagulant |
-- |
BthMP 40
|
P-I; 23.5 kDa; hemorrhagic; α-fibrinogenase |
-- |
Anticoagulant in vivo |
Fibrinolytic |
BmooPAi 42
|
PIII, 32 kDa, non-proteolytic, non-hemorrhagic |
Activation of aggregation |
-- |
-- |
Moojenactivase43,44
|
PIII; 85.7 kDa, non-hemorrhagic; α-fibrinogenase |
Activation of aggregation |
Procoagulant in vitro Activation of factors II and X; |
Non-fibrinolytic |
Moojenin 45
|
PIII; 45 kDa; non-hemorrhagic; α-fibrinogenase |
-- |
Procoagulant in vitro Anticoagulant in vivo |
-- |
Serine proteases
|
Batroxobin (Defibrase®) 24,61
|
25.5 kDa; thrombin-like |
-- |
Fibrinogenolytic Procoagulant in vitro Anticoagulant in vivo |
Fibrinolytic |
BmooSP 55
|
~30 kDa; thrombin-like |
Activation of aggregation |
Fibrinogenolytic Procoagulant in vitro Anticoagulant in vivo |
Fibrinolytic |
Moojase 56
|
30.3 kDa; thrombin-like |
Activation of aggregation |
Fibrinogenolytic Procoagulant in vitro Anticoagulant in vivo |
Fibrinolytic |
MSP 1 50,51
|
2 chains: 34 and 32.5 kDA |
Activation of aggregation |
αβγ-Fibrinogenolytic |
Fibrinolytic |
MSP 2 50,51
|
38 kDa |
Activation of aggregation |
αβγ-Fibrinogenolytic |
Fibrinolytic |
BM-IIB32 85
|
~32 kDa; thrombin-like |
-- |
αβ-Fibrinogenolytic Procoagulant in vitro |
-- |
BM-IIB35 85
|
~35 kDa; thrombin-like |
-- |
α-Fibrinogenolytic Procoagulant in vitro |
-- |
PLA2s
|
BmooPLA2 68
|
13.6 kDa; Asp49 |
Inhibition of aggregation |
-- |
-- |
BmooTX-I 67
|
15 kDa; Asp49 |
Activation of aggregation |
-- |
-- |
MjTX-III 69
|
13.8 kDa; Lys49 |
-- |
Extends blood clotting time |
Neutralizes heparin |
MjTX-IV 69
|
13.8 kDa; Lys49 |
-- |
Extends blood clotting time |
Neutralizes heparin |
Other classes
|
Baltetin 82
|
Snaclec, 25 kDa |
Inhibition of aggregation |
-- |
-- |
BmLec 81
|
Snaclec, 16.3 kDa |
Activation of aggregation |
-- |
-- |
BmooAi 83
|
New toxin, 15.2 kDa |
Inhibition of aggregation |
-- |
-- |
BmooLAAO-I 32
|
LAAO, 64.9 kDa |
Activation of aggregation |
-- |
-- |