Huang, C1717. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.
|
Hospitalized (ICU vs Non-ICU) |
Wuhan, China Jinyintan Hospital |
49 (41–58) |
73 |
15 |
28 |
13 |
|
41 |
Zhou, F1818. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-62.
|
Hospitalized (Survivors vs Non-survivors) |
Wuhan, China Jinyintan Hospital and Pulmonary Hospital |
56 (46–67) |
62 |
30 HTN 19 DM 8 CAD |
|
|
54 |
191 |
Wang, D77. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-9.
|
Hospitalized (ICU vs Non-ICU) |
Wuhan, China Zhongnan Hospital |
56 (42-68) |
75 |
20 |
102 |
36 |
|
138 |
Shi, S1919. Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, et al. Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802-10.
|
Hospitalized (Cardiac injury vs without cardiac injury) |
Wuhan, China Renmin Hospital |
64 (range 21-95) |
49.3 |
30.5 HTN 14.4 DM 10.6 CAD |
|
|
|
416 |
Guo, T 88. Guo T, Fan Y, Chen M, Wu X, Zhang L, He T, et al. Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020;5(7):811-8.
|
Hospitalized (Cardiac injury vs without cardiac injury) |
Wuhan, China Seventh Hospital |
58.5 (14.7) |
48.7 |
32.6 HTN 15.0 DM 11.2 CAD |
|
|
|
187 |
Yang, X2020. Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020;8(5):475-81.
|
ICU (survivors vs non-survivors) |
Wuhan, China Jinyintan Hospital |
59.7 (13.3) |
67 |
10 |
|
52 |
32 |
|
Ruan, Q2121. Ruan Q, Yang K, Wang W, et al. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. 2020;46(5):846-8.
|
Hospitalized (survivors vs non-survivors) |
Wuhan, China Jinyintan Hospital |
50 (44-81) 67 (15-81) |
68 |
8.7 |
|
|
68 |
|
Zhou, B2222. Zhou B, She J, Wang Y, Jiang L, Song J. The clinical characteristics of myocardial injury in severe and very severe patients with 2019 novel coronavirus disease. J Infect. 2020;81(1):147-8.
|
Hospitalized (Severe vs Very Severe) |
Wuhan, China Tongji Medical College |
63 (58-69) 67 (66-75) |
50 |
0
|
26 SEVERE
|
8 VERY SEVERE
|
|
|
Yang, F2323. Yang F, Shi S, Zhu J, Shi J, Dai K, Chen X. Analysis of 92 deceased patients with COVID-19. J Med Virol. 2020;92(11):2511-5.
|
Non-survivors |
Wuhan, China Renmin Hospital |
69.8 (15) |
53.3 |
17.4 |
|
|
92 |
|
Deng, Q2424. Deng Q, Hu B, Zhang Y, Wang H, Zhou X, Hu W, et al. Suspected myocardial injury in patients with COVID-19: evidence from front-line clinical observation in Wuhan, China. Int J Cardiol. 2020 Jul 13;311:116-21.
|
Hospitalized (Severe vs Very Severe) |
Wuhan, China Renmin Hospital |
65 (49-71) |
50.9 |
32.1 HTN 17.0 DM 13.4 CAD |
45 NON-SEVERE
|
67 SEVERE
|
|
112 |
Aggarwal, S2525. Aggarwal S, Garcia-Telles N, Aggarwal G, Lavie C, Lippi G, Henry BM. Clinical features, laboratory characteristics, and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19): early report from the United States. Diagnosis (Berl). 2020;7(2):91-6.
|
Hospitalized (Severe vs non-severe) |
Iowa, USA UnityPoint, Des Moines Hospital |
67 (range 38-95) |
75 |
57 HTN 19 DM 19 CAD |
|
|
|
16 |
Wei, J2626. Wei JF, Huang FY, Xiong TY, Liu Q, Chen H, Wang H, et al. Acute myocardial injury is common in patients with covid-19 and impairs their prognosis. Heart. 2020;106(15):1154-9.
|
Hospitalized (Cardiac injury vs without cardiac injury) |
Sichuan, China Chengdu and West China Hospital |
49 (34-62) |
54 |
21 HTN 14 DM 5 CAD |
|
|
|
101 |
Li, D2727. Li D, Chen Y, Jia Y, Tong L, Wang W, Liu Y, et al. SARS-CoV-2-induced immune dysregulation and myocardial injury risk in China: insights from the ERS-COVID-19 study. Circ Res. 2020;127(3):397-9.
|
Hospitalized (Cardiac injury vs without cardiac injury) |
China ERS-COVID-19 study (2 hospitals)2828. Chinese Clinical Trial Register [Internet]. West China Hospital, Sichuan University. 2020 Mar 05 - . Identifier ChiCTR2000030494, Early risk stratification of the novel coronavirus infected diseases (COVID-19): a multicenter retrospective study (ERS-COVID-19 study). [citado 30 jan 2020]. Disponível em: http://www.chictr.org.cn. http://www.chictr.org.cn...
|
CI 71 (66-83), No CI 60 (48-68) |
CI 24 (61.5), No CI 75 (52.4) |
0
|
|
|
|
182 |
Shi, S2929. Shi S, Qin M, Cai Y, Liu T, Shen B, Yang F, et al. Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019. Eur Heart J. 2020;41(22):2070-9.
|
Severe and critical hospitalized patients (survivors vs non-survivors) |
Wuhan, China Renmin Hospital |
63 (50– 72) |
48 |
29.7 HTN 14.5 DM 8.9 CAD |
|
671 |
62 |
|
Ni, W3030. Ni W, Yang X, Liu J, Bao J, Li R, Xu Y, et al. Acute myocardial injury at hospital admission is associated with all-cause mortality in COVID-19. J Am Coll Cardiol. 2020;76(1):124-5.
|
Hospitalized (survivors vs non-survivors) |
Wuhan, China Central Hospital |
67 (57–73) |
57.4 |
49.3 HTN 26.7 DM 14.2 CAD |
|
|
60 |
176 |
Yang, Q3131. Yang Q, Xie L, Zhang W, Zhao L, Wu H, Jiang JJ, et al. Analysis of the clinical characteristics, drug treatments and prognoses of 136 patients with coronavirus disease 2019. J Clin Pharm Ther. 2020;45(4):609-16.
|
Hospitalized (moderate vs severe or critical) |
Wuhan, China Third Hospital |
56 (44-64) |
48.5 |
27.1 HTN 14.7 DM |
103 MODERATE
|
33 SEVERE/CRITICAL
|
|
136 |
Zhao, M3232. Zhao M, Wang M, Zhang J, Gu J, Zhang P, Xu Y, et al. Comparison of clinical characteristics and outcomes of patients with coronavirus disease 2019 at different ages. Aging (Albany NY). 2020;12(11):10070-86.
|
Hospitalized |
Wuhan, China Renmin Hospital |
61 (46-70) |
46.6 |
28.2 HTN 11.8 DM 6 CAD |
|
|
|
1000 |
Arentz, M3333. Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX, Chong M, et al. Characteristics and outcomes of 21 critically Ill patients With COVID-19 in Washington State. JAMA. 2020;323(16):1612-4.
|
Hospitalized in ICU |
Washington state, USA Evergreen Hospital |
70 (range, 43-92) |
52 |
33.3 DM |
|
21 |
|
|
Richardson, S3434. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA. 2020;323(20):2052-9.
|
Hospitalized |
12 hospitals in New York, USA |
63 (52-75) |
60.3 |
56.6 HTN 33.8 DM 11.1 CAD |
|
|
|
3522 |
Suleyman, G1616. Suleyman G, Fadel RA, Malette KM, Hammond C, Abdulla H, Entz A, et al. Clinical characteristics and morbidity associated with coronavirus disease 2019 in a series of patients in Metropolitan Detroit. JAMA Netw Open. 2020;3(6):e2012270.
|
Admitted to Emergency department |
Hospitals in Henry Ford Health System in Detroit, Michigan, USA |
57.5 (16.8) |
44.1 |
63.7 HTN 38.4 DM 12.7 CAD |
214 |
141 |
|
355 |
Total number of participants |
518 |
1042 |
368 |
6573 |