Sudden cardiac death |
0.0007 |
0.0003 |
Beta |
(1010. Zhang S, Ching C-K, Huang D, Liu Y-B, Rodriguez-Guerrero DA, Hussin A, et al. Utilization of implantable cardioverter-defibrillators for the prevention of sudden cardiac death in emerging countries: Improve SCA clinical trial. [Internet]. 17th ed. Vol. 17, Heart rhythm. United States; 2020. p. 468–75.[Cited in 2018 June 15]. Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/31561030 https://pubmed-ncbi-nlm-nih-gov.libconte...
) |
Non-sudden cardiac death |
0.0014 |
0.0004 |
Beta |
Non-cardiac death |
0.0005 |
0.0003 |
Beta |
Unknown death |
0.0013 |
0.0003 |
Beta |
Monthly Risk of Mortality (No ICD Therapy)
|
Sudden cardiac death |
0.0028 |
0.0005 |
Beta |
(1010. Zhang S, Ching C-K, Huang D, Liu Y-B, Rodriguez-Guerrero DA, Hussin A, et al. Utilization of implantable cardioverter-defibrillators for the prevention of sudden cardiac death in emerging countries: Improve SCA clinical trial. [Internet]. 17th ed. Vol. 17, Heart rhythm. United States; 2020. p. 468–75.[Cited in 2018 June 15]. Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/31561030 https://pubmed-ncbi-nlm-nih-gov.libconte...
) |
Non-sudden cardiac death |
0.0021 |
0.0004 |
Beta |
Non-cardiac death |
0.0010 |
0.0004 |
Beta |
Unknown death |
0.0014 |
0.0004 |
Beta |
ICD-Related Probabilities
|
Initial operative death |
0.0002 |
0.00002 |
Beta |
(1313. Hammill SC, Kremers MS, Stevenson LW, Heidenreich PA, Lang CM, Curtis JP, et al. Review of the registry’s fourth year, incorporating lead data and pediatric ICD procedures, and use as a national performance measure. [Internet]. 7th ed. Vol. 7, Heart rhythm. United States; 2010. p. 1340–5. Available from: [Cited in 2019 aug 26].https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/20647056 https://pubmed-ncbi-nlm-nih-gov.libconte...
) |
Continue ICD therapy after shock |
0.0034 |
0.0002 |
Beta |
(22. Moss AJ, Schuger C, Beck CA, Brown MW, Cannom DS, Daubert JP, et al. Reduction in inappropriate therapy and mortality through ICD programming. [Internet]. 367th ed. Vol. 367, The New England journal of medicine. United States; 2012. p. 2275–83. [Cited in 2020 Jul 12] Available from: https://pubmed.ncbi.nlm.nih.gov/23131066 https://pubmed.ncbi.nlm.nih.gov/23131066...
,1414. Gasparini M, Proclemer A, Klersy C, Kloppe A, Lunati M, Ferrer JBM, et al. Effect of long-detection interval vs standard-detection interval for implantable cardioverter-defibrillators on antitachycardia pacing and shock delivery: the ADVANCE III randomized clinical trial. [Internet]. 309th ed. Vol. 309, JAMA. United States; 2013. p. 1903–11. [Cited in 2020 June 12].Available from: https://pubmed.ncbi.nlm.nih.gov/23652522 https://pubmed.ncbi.nlm.nih.gov/23652522...
,1515. Saeed M, Hanna I, Robotis D, Styperek R, Polosajian L, Khan A, et al. Programming implantable cardioverter-defibrillators in patients with primary prevention indication to prolong time to first shock: results from the PROVIDE study. [Internet]. 25th ed. Vol. 25, Journal of cardiovascular electrophysiology. United States; 2014. p. 52–9.[Cited in 2018 June 21]. Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/24112717 https://pubmed-ncbi-nlm-nih-gov.libconte...
,1919. Li H, Natale A, Zhu W, Greenfield RA, Easley A, Barrington W, et al. Causes and consequences of discontinuation of the implantable cardioverter-defibrillator therapy in non-terminally ill patients. [Internet]. 81st ed. Vol. 81, The American journal of cardiology. United States; 1998. p. 1203–5.[Cited in 2017 May 12]. Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/9604946 https://pubmed-ncbi-nlm-nih-gov.libconte...
,3535. Auricchio A, Schloss EJ, Kurita T, Meijer A, Gerritse B, Zweibel S, et al. Low inappropriate shock rates in patients with single- and dual/triple-chamber implantable cardioverter-defibrillators using a novel suite of detection algorithms: PainFree SST trial primary results. [Internet]. 12th ed. Vol. 12, Heart rhythm. United States; 2015. p. 926–36.[Cited in 2019 Apr 16]. Available from: https://pubmed.ncbi.nlm.nih.gov/25637563 https://pubmed.ncbi.nlm.nih.gov/25637563...
,3636. Sweeney MO, Wathen MS, Volosin K, Abdalla I, DeGroot PJ, Otterness MF, et al. Appropriate and inappropriate ventricular therapies, quality of life, and mortality among primary and secondary prevention implantable cardioverter defibrillator patients: results from the Pacing Fast VT REduces Shock ThErapies (PainFREE Rx II) trial. [Internet]. 111th ed. Vol. 111, Circulation. United States; 2005. p. 2898–905.[Cited in 202o may 23]. Available from: https://pubmed.ncbi.nlm.nih.gov/15927965 https://pubmed.ncbi.nlm.nih.gov/15927965...
) |
Discontinue ICD therapy after shock |
0.0001 |
0.00007 |
Beta |
Lead replacement (initial implant) |
0.0004 |
0.0005 |
Beta |
(1818. Ghani A, Delnoy PPHM, Ramdat Misier AR, Smit JJJ, Adiyaman A, Ottervanger JP, et al. Incidence of lead dislodgement, malfunction and perforation during the first year following device implantation. [Internet]. 22nd ed. Vol. 22, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation. Netherlands; 2014. p. 286–91. [Cited in 2020 May 17].Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/24807834 https://pubmed-ncbi-nlm-nih-gov.libconte...
,2222. Providencia R, Kramer DB, Pimenta D, Babu GG, Hatfield LA, Ioannou A, et al. Transvenous Implantable Cardioverter-Defibrillator (ICD) Lead Performance: A Meta-Analysis of Observational Studies. [Internet]. 4th ed. Vol. 4, Journal of the American Heart Association. England; 2015. p. 2047–9980. [Cited in 2020 Jul 25].Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/26518666 https://pubmed-ncbi-nlm-nih-gov.libconte...
) |
Lead replacement (replacement implant) |
0.0008 |
0.0009 |
Beta |
(2323. Poole JE, Gleva MJ, Mela T, Chung MK, Uslan DZ, Borge R, et al. Complication rates associated with pacemaker or implantable cardioverter-defibrillator generator replacements and upgrade procedures: results from the REPLACE registry. [Internet]. 122nd ed. Vol. 122, Circulation. United States; 2010. p. 1553–61. [Cited in 2020 May 22]. Available from: https://libcontent.medtronic.com:2908/pubmed/20921437 https://libcontent.medtronic.com:2908/pu...
) |
Lead dislodgement (initial implant) |
0.018 |
0.0012 |
Beta |
(1818. Ghani A, Delnoy PPHM, Ramdat Misier AR, Smit JJJ, Adiyaman A, Ottervanger JP, et al. Incidence of lead dislodgement, malfunction and perforation during the first year following device implantation. [Internet]. 22nd ed. Vol. 22, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation. Netherlands; 2014. p. 286–91. [Cited in 2020 May 17].Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/24807834 https://pubmed-ncbi-nlm-nih-gov.libconte...
,2222. Providencia R, Kramer DB, Pimenta D, Babu GG, Hatfield LA, Ioannou A, et al. Transvenous Implantable Cardioverter-Defibrillator (ICD) Lead Performance: A Meta-Analysis of Observational Studies. [Internet]. 4th ed. Vol. 4, Journal of the American Heart Association. England; 2015. p. 2047–9980. [Cited in 2020 Jul 25].Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/26518666 https://pubmed-ncbi-nlm-nih-gov.libconte...
) |
Lead dislodgement (replacement implant) |
0.005 |
0.0009 |
Beta |
(2323. Poole JE, Gleva MJ, Mela T, Chung MK, Uslan DZ, Borge R, et al. Complication rates associated with pacemaker or implantable cardioverter-defibrillator generator replacements and upgrade procedures: results from the REPLACE registry. [Internet]. 122nd ed. Vol. 122, Circulation. United States; 2010. p. 1553–61. [Cited in 2020 May 22]. Available from: https://libcontent.medtronic.com:2908/pubmed/20921437 https://libcontent.medtronic.com:2908/pu...
) |
ICD infection (initial implant) |
0.0244 |
0.0049 |
Beta |
(1717. Hussein AA, Baghdy Y, Wazni OM, Brunner MP, Kabbach G, Shao M, et al. Microbiology of Cardiac Implantable Electronic Device Infections. [Internet]. 2nd ed. Vol. 2, JACC. Clinical electrophysiology. United States; 2016. p. 498–505. [Cited in 2019 Feb 21].Available from: https://libcontent.medtronic.com:2908/pubmed/29759872 https://libcontent.medtronic.com:2908/pu...
) |
ICD infection (replacement implant) |
0.0432 |
0.0064 |
Beta |
(2020. Eby E, LGS B, MP J. Economic impact of cardiac implantable electronic device infections: cost analysis at one year in a large US health insurer [Internet]. 2020.{Cited in 2016 May 29] Available from: https://www.tandfonline.com/doi/abs/10.1080/13696998.2020.1751649 https://www.tandfonline.com/doi/abs/10.1...
) |
Costs, 2018 Brazilian Reals (R$)
|
ICD implant procedure (initial) |
R$1,738 |
|
|
(3737. Brasil. Ministério da Saúde. Edital Do Pregao Eletronico No 22/2018 Sistema De Registro De Precos. Brasilia; 2018.) |
ICD implant procedure (replacement) |
R$1,738 |
|
|
Lead replacement |
R$827 |
|
|
ICD generator removal |
R$742 |
|
|
ICD lead dislodgement |
R$742 |
|
|
ICD inappropriate shock |
R$500 |
|
|
ICD infection |
R$30,000 |
|
|
Monthly inpatient cost |
R$166 |
|
|
Monthly outpatient cost |
R$354 |
|
|
Utility
|
Annual utility of heart failure patient |
0.837 |
0.007 |
Beta |
(1010. Zhang S, Ching C-K, Huang D, Liu Y-B, Rodriguez-Guerrero DA, Hussin A, et al. Utilization of implantable cardioverter-defibrillators for the prevention of sudden cardiac death in emerging countries: Improve SCA clinical trial. [Internet]. 17th ed. Vol. 17, Heart rhythm. United States; 2020. p. 468–75.[Cited in 2018 June 15]. Available from: https://pubmed-ncbi-nlm-nih-gov.libcontent.medtronic.com:2443/31561030 https://pubmed-ncbi-nlm-nih-gov.libconte...
) |
ICD complication state |
0.7408 |
0.0112 |
Beta |