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Direct, rapid and convenient synthesis of esters and thioesters using PPh3/N-chlorobenzotriazole system

We have developed an efficient method for esterification and thioesterification of various carboxylic acids with different alcohols and thiols using PPh3/N-chlorobenzotriazole mixed reagent in CH2Cl2 at room temperature.

PPh3; N-chlorobenzotriazole (NCBT); esters; thioesters


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