The hexane phase from the ethanol extract from leaves of Guarea macrophylla (Meliaceae) was submitted to chromatographic separation. These procedures allowed the isolation of one new diterpenoid: 7alpha-hydroperoxy-isopimara-8(14),15-diene-2alpha,3beta-diol, one new nor-diterpenoid: 19-nor-isopimara-7,15,4(18)-trien-3-one besides seven known diterpenoids. Their structures were deduced by analysis of spectrometric data and comparison of data described in the literature.
Guarea macrophylla; diterpenoids; 7alpha-hydroperoxy-isopimara-8(14),15-diene-2alpha,3beta-diol; 19-nor-isopimara-7,15,4(18)-trien-3-one
