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Articles • J. Braz. Chem. Soc. 26 (7) • July 2015 • https://doi.org/10.5935/0103-5053.20150102   copy

Fast Microwave-Assisted Resolution of (±)-Cyanohydrins Promoted by Lipase from Candida antarctica

Authorship SCIMAGO INSTITUTIONS RANKINGS

Enzymatic kinetic resolution (EKR) of (±)-cyanohydrins was performed by using immobilized lipase from Candida antarctica (CALB) under conventional ordinary conditions (orbital shaking) and under microwave radiation (MW). The use of microwave radiation contributed very expressively on the reduction of the reaction time from 24 to 2 h. Most importantly, high selectivity (up to 92% eep) as well as conversion was achieved under MW radiation (50-56%).

Keywords:
CALB; biocatalysis; enzymatic resolution; microwave radiation; cyanohydrins

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