The reaction of ethyl (p-methoxyphenylimino)acetate with propargyl bromide mediated by activated zinc powder afforded alkynyl amine, which was then reacted with a variety of organic azides using a microwave energy source, leading to β-1,2,3-triazolyl-α-amino esters in good yield.
Keywords:
microwave; amino ester; click chemistry; addition reaction; 1,2,3-triazole