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New triterpene and antibacterial labdenoic acid derivatives from Moldenhawera nutans

A new triterpene derivative (22beta-hydroxylupeol) was isolated from the MeOH extract of stems of Moldenhawera nutans (Leguminosae) together with labdenoic acid derivatives of common occurrence in this species. From the labd-8(17)-en-15-oic acid were prepared simple derivatives, which exhibited in vitro weak activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella cholerasuis, and Vibrio parahaemolyticus.

Moldenhawera nutans; Leguminosae; antibacterial labdene derivatives; 22beta-hydroxylupeol


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