Apparent molar volume (Vphi), partial molar volume (V), solute-solute interaction parameter (Sv), partial molar expansivity (E(0)2) and isobaric thermal expansion coefficient (alpha2) of mefenamic acid in six different organic solvents namely, methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, and 2-butanol, have been calculated from the measured solution densities over a temperature range of T=293.15 and T=313.15±0.1K. The solution densities were measured by an automated vibrating tube densitymeter (Anton Paar DMA-48). The molality range investigated was between 6×10-3 and 3.25 ×10-2 mol kg -1. The effect of temperature on apparent molar volume and partial molar volume was also determined. Decrease in solute-solvent interactions with an increase in temperature has been noted. Partial molar volume of mefenamic acid changes with the change in solvent polarity.
apparent molar volume; partial molar volume; mefenamic acid; partial molar expansivity; alcohol
