An unusual case of intraosseous mucoepidermoid carcinoma is reported in a 22-year-old female, located in the posterior maxilla region. The article summarizes the main characteristics of the disease, including clinical-pathologic characteristics, treatment and prognosis.
Key words:
mucoepidermoid carcinoma; oral diagnosis; immunohistochemistry
A) coronal section; B) axial section; C) sagital section.
A) alcian blue-PAS; B) mucicarmin.
PAS: periodic acid Schiff.
A) AE1/AE3; B) CK7; C) CK19.
CK: cytokeratin.
A) complete surgical resection of the tumor was performed; B) maxillary provisional obturator prosthesis was placed for rehabilitation.
| Author | Year | Age | Sex | Symptoms | Radiographic features | Clinical diagnostic hypothesis | Treatment |
|---|---|---|---|---|---|---|---|
| Namin et al.(1313 Namin AK, Moshref M, Shahoon H, et al. Intraosseous mucoepidermoid carcinoma of the maxilla in a teenager: a case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005; 100: 93-6.) | 2005 | 11 | F | Pain | Radiolucent multilocular | Infectious lesion | Left hemimaxillectomy |
| Raut, Khedkar(1414 Raut D, Khedkar S. Primary intraosseous mucoepidermoid carcinoma of the maxilla: a case report and review of literature. Dentomaxillofac Radiol. 2009; 38: 163-8.) | 2009 | 40 | M | Pain | Radiolucent unilocular | OC, nasopalatine duct cyst | Right maxillectomy with neck dissection |
| Sherin et al.(1515 Sherin S, Sherin N, Thomas V, et al. Central mucoepidermoid carcinoma of maxilla with radiographic appearance of mixed radiopaque-radiolucent lesion: a case report. Dentomaxillofac Radiol. 2011; 40: 463-5.) | 2011 | 29 | F | Asymptomatic | Radiolucent multilocular | Fibroosseous lesion, benign salivary gland tumor and vascular lesion | Radical resection and adjuvant radiotherapy |
| Takano et al.(1616 Takano M, Kasahara K, Matsui S, et al. A case of mucoepidermoid carcinoma associated with maxillary cyst. Bull Tokyo Dent Coll. 2012; 53: 119-25.) | 2012 | 18 | M | Asymptomatic | Radiolucent multilocular | OC | Right maxillectomy with neck dissection |
| Lakouichmi et al.(1717 Lakouichmi M, Touati MM, Zrara I, et al. Primary intraosseous mucoepidermoid carcinoma of the jaws. Rev Stomatol Chir Maxillofac Chir Orale. 2013; 114: 334-7.) | 2013 | 42 | F | Pain | Radiolucent multilocular | Cystic lesion | NI |
| Chan et al.(1818 Chan KC, Pharoah M, Lee L, et al. Intraosseous mucoepidermoid carcinoma: a review of the diagnostic imaging features of four jaw cases. Dentomaxillofac Radiol. 2013; 42: 20110162.) | 2013 | 51 | F | Asymptomatic | Multilocular/mixed | NI | NI |
| Chan et al.(1818 Chan KC, Pharoah M, Lee L, et al. Intraosseous mucoepidermoid carcinoma: a review of the diagnostic imaging features of four jaw cases. Dentomaxillofac Radiol. 2013; 42: 20110162.) | 2013 | 42 | M | Asymptomatic | Radiolucent multilocular | NI | NI |
| Rathore et al.(1919 Rathore AS, Ahuja P, Chhina S, et al. Primary intraosseous mucoepidermoid carcinoma of maxilla. J Oral Maxillofac Pathol. 2014; 18: 428-31.) | 2014 | 18 | M | Pain | Radiolucent unilocular | Cystic lesion | Right maxillectomy with neck dissection |
| Suresh et al.(2020 Suresh D, Raviraj J, Vijaykumar B, et al. Central mucoepidermoid carcinoma of the maxilla with unusual ground glass appearance and calcifications: a case report. Imaging Sci Dent. 2014; 44: 161-4.) | 2014 | 52 | M | Asymptomatic | Multilocular/mixed | Osteosarcoma and metastatic tumor | NI |
| Nallamilli et al.(1111 Nallamilli SM, Tatapudi R, Reddy RS, et al. Primary intraosseous mucoepidermoid carcinoma of the maxilla. Ghana Med J. 2015; 49: 120-3.) | 2015 | 36 | M | Pain | Radiolucent unilocular | OT | NI |
| Martins et al.(2121 Martins TH, Bonardi JP, Stabile GA. Mucoepidermoid carcinoma of the hard palate in a young patient. J Craniofac Surg. 2016; 27: e598-e9.) | 2016 | 17 | M | Asymptomatic | Hypodense image with well-defined edges involving dental apex of the elements 13, 14, and 15 | OC | Right maxillectomy with neck dissection |
| Purohit et al.(2222 Purohit S, Manjunatha BS, Dagrus K, et al. Intraosseous mucoepidermoid carcinoma of maxilla: a rare entity. J Exp Ther Oncol. 2016; 11: 207-11.) | 2016 | 28 | M | Asymptomatic | Mixed radiopaque-radiolucent lesion | OC | Left hemimaxillectomy |
| Razavi et al.(2323 Razavi SM, Yahyaabadi R, Khalesi S. A case of central mucoepidermoid carcinoma associated with dentigerous cyst. Dent Res J (Isfahan). 2017; 14: 423-6.) | 2017 | 43 | F | NI | Radiolucent unilocular | OC and adenomatoid odontogenic tumor | Left hemimaxillectomy |
| Present case | 2018 | 22 | F | Pain | Radiolucent unilocular | OC | Left hemimaxillectomy |
