IL-4 |
Oliveira et al. (2009) Brasil |
Prospective |
35 patients with OSCC (26 M and 9 F) |
Tissue biopsy and immunohistochemistry |
Increased levels of IL-4 do not seem to be associated with a poorer prognosis in patients with OSCC |
Mojtahedi et al. (2012) Irã |
Cross sectional |
87 patients (control group: 53; OSCC group: 34) |
ELISA in blood samples |
Increased levels of IL-4 do not seem to be associated with a poorer prognosis in patients with OSCC |
Aziz et al. (2015) Paquistão |
Cross sectional |
63 patients [51 M and 12 F (control group: 33; OSCC group: 30) |
ELISA in saliva samples |
Increased levels of IL-4 seem to be associated with a poorer prognosis in patients with OSCC |
IL-6 |
Oliveira et al. (2009) Brasil |
Prospective |
35 patients with OSCC (26 M and 9 F) |
Tissue biopsy and immunohistochemistry |
Increased levels of IL-6 do not seem to be associated with a poorer prognosis in patients with OSCC |
Sato et al. (2010) Japão |
Prospective |
48 patients [27 M and 21 F (control group: 19; OSCC group: 29)] |
ELISA in saliva samples |
Increased levels of IL-6 seem to be associated with a poorer prognosis in patients with OSCC |
Chang et al. (2013) Taiwan |
Cross sectional |
466 patients (control group: 125; premalignant lesions group: 104; OSCC group: 237) |
ELISA in blood samples |
Increased levels of IL-6 seem to be associated with a poorer prognosis in patients with OSCC |
Juretic et al. (2013) Croácia |
Cross sectional |
57 patients [31 M e 26 F (control group: 19; premalignant lesions group: 19; OSCC group: 19)] |
ELISA in saliva samples |
Increased levels of IL-6 seem to be associated with a poorer prognosis in patients with OSCC |
Skrinjar et al. (2015) Croácia |
Prospective |
67 patients [49 M and 18 F (control group: 31; OSCC group: 36)] |
ELISA in saliva samples |
Increased levels of IL-6 seem to be associated with a poorer prognosis in patients with OSCC |
Jinno et al. (2015) Japão |
Cross sectional |
78 patients with OSCC (52 M e 26 F) |
Tissue biopsy and immunohistochemistry |
Increased levels of IL-6 seem to be associated with a poorer prognosis in patients with OSCC |
Panneer e Sdaksharam (2015) India |
|
75 patients [63 M e 12 F (control group: 25; leukoplakia group: 25; OSCC group: 25)] |
ELISA in saliva samples |
Increased levels of IL-6 seem to be associated with a poorer prognosis in patients with OSCC |
IL-8 |
Oliveira et al. (2009) Brasil |
Prospective |
35 patients with OSCC (26 M and 9 F) |
Tissue biopsy and immunohistochemistry |
Increased levels of IL-8 do not seem to be associated with a poorer prognosis in patients with OSCC |
Fujita et al. (2014) Japão |
Cross sectional |
58 patients [37 M and 21 F (control group: 8; OSCC group: 50)] |
ELISA in blood samples |
Increased levels of IL-8 seem to be associated with a poorer prognosis in patients with OSCC |
Rajkumar et al. (2014) India |
Cross sectional |
300 patients [204 M and 96 F (control group: 100; leukoplakia group: 50; submucous fibrosis group: 50; OSCC group: 100)] |
ELISA in saliva and blood samples |
Increased levels of IL-8 seem to be associated with a poorer prognosis in patients with OSCC |
IL-10 |
Alhamarneh et al. (2011) Reino Unido |
Cross sectional |
61 patients (control group: 40; OSCC group: 21) |
ELISA in blood samples |
Increased levels of IL-10 do not seem to be associated with a poorer prognosis in patients with OSCC |
Green et al. (2012) Inglaterra |
Cross sectional |
61 patients (control group: 40; OSCC group: 21) |
ELISA in blood samples |
Increased levels of IL-10 do not seem to be associated with a poorer prognosis in patients with OSCC |
Mojtahedi et al. (2012) Irã |
Cross sectional |
87 patients (control group: 53; OSCC group: 34) |
ELISA in blood samples |
Increased levels of IL-10 do not seem to be associated with a poorer prognosis in patients with OSCC |
Chen et al. (2013) Taiwan |
Cross sectional |
325 patients (252 M and 73 F) |
Tissue biopsy and immunohistochemistry |
Increased levels of IL-10 seem to be associated with a poorer prognosis in patients with OSCC |
Wang et al. (2014) China |
Cross sectional |
Group with OSCC: 240 (152 M and 88 F) |
Tissue biopsy and immunohistochemistry |
Increased levels of IL-10 seem to be associated with a poorer prognosis in patients with OSCC |
Aziz et al. (2015) Paquistão |
Cross sectional |
63 patients [51 M and 12 F (control group: 33; OSCC group: 30)] |
ELISA in saliva samples |
Increased levels of IL-10 seem to be associated with a poorer prognosis in patients with OSCC |
IL-12 |
Oliveira et al. (2009) Brasil |
Prospective |
35 patients with OSCC (26 M and 9 F) |
Tissue biopsy and immunohistochemistry |
Increased levels of IL-12 do not seem to be associated with a poorer prognosis in patients with OSCC |
Green et al. (2012) Inglaterra |
Cross sectional |
61 patients (control group: 40; OSCC group: 21)] |
ELISA in blood samples |
Increased levels of IL-12 do not seem to be associated with a poorer prognosis in patients with OSCC |
IL-13 |
Aziz et al. (2015) Paquistão |
Cross sectional |
63 patients [51 M and 12 F (control group: 33; OSCC group: 30)] |
ELISA in saliva samples |
Increased levels of IL-13 seem to be associated with a poorer prognosis in patients with OSCC |