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Empyema and bacteremic pneumococcal pneumonia in children under five years of age* * Study carried out at the University of São Paulo School of Public Health, São Paulo, Brazil; the Federal University of Bahia School of Medicine, Salvador, Brazil; the Pedro de Elizalde Children's Hospital, Buenos Aires, Argentina; the Santa Casa School of Medical Sciences in São Paulo, São Paulo, Brazil; the Durand Municipal Hospital, Buenos Aires, Argentina; the Martagão Gesteira Institute of Pediatrics and Child Care, Rio de Janeiro, Brazil; the Center for Meningitis, Pneumonia, and Pneumococcal Infections, Department of Bacteriology, Adolfo Lutz Institute, São Paulo, Brazil; the Pernambuco Mother and Child Institute, Recife, Brazil; the Dr. Robert Reid Cabral Children's Hospital, Santo Domingo, Dominican Republic; the Department of Child and Adolescent Health and Development, Pan American Health Organization, Washington, DC, USA; and the Department of Pediatric Pulmonology, Federal University of Minas Gerais Hospital das Clínicas, Belo Horizonte, Brazil. , ** * Study carried out at the University of Southern Santa Catarina, Tubarão, Brazil.

We compared bacteremic pneumococcal pneumonia (BPP) and pneumococcal empyema (PE), in terms of clinical, radiological, and laboratory findings, in under-fives. A cross-sectional nested cohort study, involving under-fives (102 with PE and 128 with BPP), was conducted at 12 centers in Argentina, Brazil, and the Dominican Republic. Among those with PE, mean age was higher; disease duration was longer; and tachypnea, dyspnea, and high leukocyte counts were more common. Among those with BPP, fever and lethargy were more common. It seems that children with PE can be distinguished from those with BPP on the basis of clinical and laboratory findings. Because both conditions are associated with high rates of morbidity and mortality, prompt diagnosis is crucial.

Empyema, pleural; Pneumonia, pneumococcal; Pneumococcal infections


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