Kappa-ViTX
|
MMFRLTSVSCFLLVIACLNLFQVVLTSRCFPPGIYCTPYLPCCWGICCGTCRNVCHLRIGKRATFQE |
67 7,599 |
XI (C-C-CC-CC-C-C) |
(I2) S.Family κ-Conotoxin |
Impairing of VG-K+ ion channels |
[5050. Kauferstein S, Huys I, Lamthanh H, Stöcklin R, Sotto F, Menez A, Tytgat J, Mebs D. A novel conotoxin inhibiting vertebrate voltage-sensitive potassium channels. Toxicon. 2003 Jul;42(1):43-52. ] |
Alpha-ViIA
|
MGMRMMFVVFLLVVFASSVTLDRASYGRYASPVDRASALIAQAILRDCCSNPPCAHNNPDCR |
62 6,810 |
I (CC-C-C) |
(A) S.Family α-Conotoxin |
Inhibiting nAChR |
[5151. Li L, Liu N, Ding R, Wang S, Liu Z, Li H, Zheng X, Dai Q. A novel 4/6-type alpha-conotoxin ViIA selectively inhibits nAchR α3β2 subtype. Acta Biochim Biophys Sin (Shanghai). 2015 Dec;47(12):1023-8.] |
Contryphan-Vi
|
MGKLTILVLVAAVLLSTQVMVQGDGDQPADRNAVRRDDNPGGLSGKFMNVLRRSGCPWHPWCG |
63 6,806 |
C-C |
(O2) S.Family Contryphan Family |
Impairing VG-Ca2+ and KCa channels |
[5252. Liu Z, Li H, Liu N, Wu C, Jiang J, Yue J, Jing Y, Dai Q. Diversity and evolution of conotoxins in Conus virgo, Conus eburneus, Conus imperialis and Conus marmoreus from the South China Sea. Toxicon. 2012 Nov;60(6):982-9. ">] |
ViVA
|
MRCVPVFIILLLLIPSASSAAVQPKTEKDDVPLASVHDSALRILSRQCCITIPECCRIG |
59 6,393 |
V (CC-CC) |
(T) S.Family |
Unknown |
[5353. Quinton L, Le Caër JP, Vinh J, Gilles N, Chamot-Rooke J. Fourier transform mass spectrometry: a powerful tool for toxin analysis. Toxicon. 2006 May;47(6):715-26. ] |
ViVB
|
MRCVPVFIILLLLIPSAPSAAVQPKTEKDDVPLASFHDSAMRILSRQCCPTIPECCRVG |
59 6,439 |
V (CC-CC) |
(T) S.Family |
Unknown |
[5353. Quinton L, Le Caër JP, Vinh J, Gilles N, Chamot-Rooke J. Fourier transform mass spectrometry: a powerful tool for toxin analysis. Toxicon. 2006 May;47(6):715-26. ] |
Vi1361
|
QCCPTMPECCRI |
12 1,384 |
V (CC-CC) |
(T) S.Family |
Unknown |
[5454. Mandal AK, Ramasamy MRS, Sabareesh V, Openshaw ME, Krishnan KS, Balaram P. Sequencing of T-superfamily conotoxins from Conus virgo: pyroglutamic acid identification and disulfide arrangement by MALDI mass spectrometry. J Am Soc Mass Spectrom. 2007 Aug;18(8):1396-404. ] |
Vi5.1a
|
MRCVPVFIILLLLIPSAPSADAQPKTKDDVPLASYHDNAERTLQRLWNQRHCCPIDLPCCPPG |
63 7,039 |
V (CC-CC) |
(T) S.Family |
Unknown |
[5555. Peng C, Wu X, Han Y, Yuan D, Chi C, Wang C. Identification of six novel T-1 conotoxins from Conus pulicarius by molecular cloning. Peptides. 2007 Nov;28(11):2116-24.] |
Vi5.1b
|
MLCVPVFIILFIIIPFAPTSESQPKTKEEVAKASVHDNAERTLQRLWNQSHCCPIDLQCCPPG |
63 7,065 |
V (CC-CC) |
(T) S.Family |
Unknown |
[5555. Peng C, Wu X, Han Y, Yuan D, Chi C, Wang C. Identification of six novel T-1 conotoxins from Conus pulicarius by molecular cloning. Peptides. 2007 Nov;28(11):2116-24.] |
Vi15a
|
MMPVILLLLLSLAIRCADGKAVQGDSDPSASLLTGDKNHDLPVKRDCTTCAGEECCGRCTCPWGDNCSCIEWGK |
74 7,887 |
XV (C-C-CC-C-C-C-C) |
(V) S.Family |
Unknown |
[5656. Peng C, Liu L, Shao X, Chi C, Wang C. Identification of a novel class of conotoxins defined as V-conotoxins with a unique cysteine pattern and signal peptide sequence. Peptides. 2008 Jun;29(6):985-91. ] |
ViKr92
|
MKLTWMMIVAVLFLTAWTFVTADDTRYKLENPFLKARNELQKLEASQLNERGCLDPGYFCGTPFLGAYCCGGICLIVCIET |
81 9,148 |
VI/VII (C-C-CC-C-C) |
(O1) S.Family δ-, μo-, κ- or ω-conotoxins |
Targets different types of ion channels |
[5757. Luo S, Zhangsun D, Lin Q, Xie L, Wu Y, Zhu X. Sequence diversity of O-superfamily conopetides from Conus marmoreus native to Hainan. Peptides. 2006 Dec;27(12):3058-68. ] |
Conotoxin 10
|
MKLTCVLIITVLFLTASQLITADYSRDQRQYRAVRLGDEMRNFKGARDCGGQGEGCYTQPCCPGLRCRGGGTGGGACQL |
79 8,508 |
VI/VII (C-C-CC-C-C) |
(O1) S.Family δ-, μo-, κ- or ω-conotoxins |
Targets different types of ion channels |
[5858. Kauferstein S, Melaun C, Mebs D. Direct cDNA cloning of novel conopeptide precursors of the O-superfamily. Peptides. 2005 Mar;26(3):361-7. ] |
Conotoxin 3
|
MKLTCVLIITVLFLTASQLITADYSRDQRQYRAVRLGDEMRNFKGARDCGGQGEGCYTQPCCPGLRCRGGGTGGGVCQL |
79 8,536 |
VI/VII (C-C-CC-C-C) |
(O1) S.Family δ-, μo-, κ- or ω-conotoxins |
Targets different types of ion channels |
[5858. Kauferstein S, Melaun C, Mebs D. Direct cDNA cloning of novel conopeptide precursors of the O-superfamily. Peptides. 2005 Mar;26(3):361-7. ] |