Murine |
1 (2A10G6) [67 67. Dai L, Song J, Lu X, Deng YQ, Musyoki AM, Cheng H, et al. Structures of the Zika virus envelope protein and its complex with a flavivirus broadly protective antibody. Cell Host Microbe. 2016 May 11;19(5):696-704. doi: 10.1016/j.chom.2016.04.013. https://doi.org/10.1016/j.chom.2016.04.0...
] |
Fusion Loop
|
Human |
1 (ZKA64) [68 68. Stettler K, Beltramello M, Espinosa DA, Graham V, Cassotta A, Bianchi S, et al. Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection. Science. 2016 Aug 19;353(6301):823-6. doi: 10.1126/science.aaf8505. https://doi.org/10.1126/science.aaf8505...
] |
DIII |
Murine |
2 (ZK54/ZV67) [69 69. Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, Gorman MJ, et al. Structural basis of Zika virus-specific antibody protection. Cell. 2016 Aug 11;166(4):1016-27. doi: 10.1016/j.cell.2016.07.020. https://doi.org/10.1016/j.cell.2016.07.0...
] |
DIII/DIII |
Human |
3 (Z3L1/Z23/Z20) [70 70. Wang Q, Yang H, Liu X, Dai L, Ma T, Qi J, et al. Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus. Sci Transl Med. 2016 Dec 14;8(369):369ra179. doi: 10.1126/scitranslmed.aai8336. https://doi.org/10.1126/scitranslmed.aai...
] |
DI, DII/ DIII, DI/DIII |
Human |
1 (ZIKV-117) [71 71. Sapparapu G, Fernandez E, Kose N, Cao B, Fox JM, Bombardi RG, et al. Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature. 2016 Dec 15;540:443-7. doi: 10.1038/nature20564. https://doi.org/10.1038/nature20564...
] |
DII |
Murine |
1 (ZV-2) [72 72. Acharya D, Bastola P, Le L, Paul AM, Fernandez E, Diamond MS, et al. An ultrasensitive electrogenerated chemiluminescence-based immunoassay for specific detection of Zika virus. Sci Rep. 2016 Aug 24;6:32227. doi: 10.1038/srep32227. https://doi.org/10.1038/srep32227...
] |
E |
Human |
1 (Z004) [73 73. Robbiani DF, Bozzacco L, Keeffe JR, Khouri R, Olsen PC, Gazumyan A, et al. Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico. Cell. 2017 May 4;169(4):597-609.e11. doi:10.1016/j.cell.2017.04.024. https://doi.org/0.1016/j.cell.2017.04.02...
] |
DIII |
Human |
1 (ZKA35) [74 74. Balmaseda A, Stettler K, Medialdea-Carrera R, Collado D, Jin X, Zambrana JV, et al. Antibody-based assay discriminates Zika virus infection from other flaviviruses. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8384-9. doi: 10.1073/pnas.1704984114. https://doi.org/10.1073/pnas.1704984114...
] |
NS1 |
Human |
2 (m301/m302) [75 75. Wu Y, Li S, Du L, Wang C, Zou P, Hong B, et al. Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III. Emerg Microbes Infect. 2017 Oct 11;6(1):1-11. doi: 10.1038/emi.2017.79. https://doi.org/10.1038/emi.2017.79...
] |
DIII |
Murine |
1 (1F12) [76 76. Zhang L, Du X, Chen C, Chen Z, Zhang L, Han Q, et al. Development and characterization of double-antibody sandwich ELISA for detection of zika virus infection. Viruses. 2018 Nov 15;10(11):634. doi: 10.3390/v10110634. https://doi.org/10.3390/v10110634...
] |
NS1 |
Murine |
2 (J5E1/J2G7) [77 77. Kim YH, Lee J, Kim YE, Chong CK, Pinchemel Y, Reisdörfer F, et al. Development of a rapid diagnostic test kit to detect IgG/IgM antibody against zika virus using monoclonal antibodies to the envelope and non-structural protein 1 of the virus. Korean J Parasitol. 2018 Feb 28;56(1):61-70. doi: 10.3347/kjp.2018.56.1.61. https://doi.org/10.3347/kjp.2018.56.1.61...
] |
E/NS1 |
Human |
1 (ZK2B10) [78 78. Li C, Gao F, Yu L, Wang R, Jiang Y, Shi X, et al. A single injection of human neutralizing antibody protects against Zika virus infection and microcephaly in developing mouse embryos. Cell Rep. 2018 May 1;23(5):1424-34. doi: 10.1016/j.celrep.2018.04.005. https://doi.org/10.1016/j.celrep.2018.04...
] |
DIII |
Human |
3 (P1F12/P1H09/P1804) [79 79. Pawley DC, Ricciardi MJ, Dikici E, Deo SK, Daunert S. highly sensitive and selective direct detection of Zika virus particles in human bodily fluids for accurate early diagnosis of infection. ACS Omega. 2019 Apr 30;4(4):6808-18. doi: 10.1021/acsomega.9b00374. https://doi.org/10.1021/acsomega.9b00374...
] |
E |
Human |
1 (ZIKV-195) [8080. Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, et al. Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1591-96. doi:10.1073/pnas.1815432116. https://doi.org/0.1073/pnas.1815432116...
] |
DI/DII |