Langbein et al.,99 Langbein WE, Collins EG, Orebaugh C, et al. Increasing exercise tolerance of persons limited by claudication pain using polestriding. J Vasc Surg. 2002;35(5):887-93. http://dx.doi.org/10.1067/mva.2002.123756. PMid:12021703. http://dx.doi.org/10.1067/mva.2002.12375...
United States |
Controlled RCT |
n = 52 (51 M and 1 W), mean age: 67.05±7.95 years |
Exercise tolerance: incremental load treadmill test, constant load treadmill test, and VO2max analysis |
G1: Nordic walking 3x per week for 24 weeks. |
G2: control group, no exercise. |
Tew et al.,1010 Tew G, Nawaz S, Zwierska I, Saxton JM. Limb-specific and cross-transfer effects of arm-crank exercise training in patients with symptomatic peripheral arterial disease. Clin Sci. 2009;117(12):405-13. http://dx.doi.org/10.1042/CS20080688. PMid:19388883. http://dx.doi.org/10.1042/CS20080688...
United Kingdom |
Controlled RCT |
n = 57 (57 M and 0 W), mean age: 70±8 years |
Exercise tolerance: test on cycle ergometer with electronic break, hand crank, VO2max analysis, blood lactate concentration, and incremental treadmill test |
G1: intermittent aerobic exercise (2 min exercise and 2 min rest) on hand crank ergometer, 2x per week, from 20 to 40 min per day, for 12 weeks. |
G2: control group, no exercises. |
Malagoni et al.,1414 Malagoni AM, Vagnoni E, Felisatti M, et al. Evaluation of patient compliance, quality of life impact and cost-effectiveness of a “test in-train out” exercise-based rehabilitation program for patients with intermittent claudication. Circ J. 2011;75(9):2128-34. http://dx.doi.org/10.1253/circj.CJ-10-1311. PMid:21712607. http://dx.doi.org/10.1253/circj.CJ-10-13...
Italy |
Uncontrolled RCT |
n = 289 (210 M and 79 W), mean age: 71±10.1 years |
Exercise tolerance: constant load treadmill test. |
All participants: 10 min walk 2x per day, 6 days per week, for 2 years. Afterwards, analysis of variables compared participants with good compliance, 13±2months (G1) with those with poor compliance, 12±2 months (G2). |
Quality of life: with SF-36 questionnaire. |
Collins et al.,1111 Collins EG, OʼConnell S, McBurney C, et al. Comparison of walking with poles and traditional walking for peripheral arterial disease rehabilitation. J Cardiopulm Rehabil Prev. 2012;32(4):210-8. http://dx.doi.org/10.1097/HCR.0b013e31825828f4. PMid:22595894. http://dx.doi.org/10.1097/HCR.0b013e3182...
United States |
Controlled RCT |
n = 103 (89 M and 14 W), mean age: 69.7±8.9 years |
Exercise tolerance: incremental load treadmill test, constant load treadmill test (before and after 6, 12, and 24 weeks) and WIQ. Tissue oxygenation: with NIRS. |
Interval exercises (low and high intensity) 3x per week for 24 weeks. |
G1: Nordic walking. |
G2: traditional walking. |
Quality of life: with SF-36 questionnaire. |
|
Dziubek et al.,1515 Dziubek W, Bulińska K, Stefańska M, et al. Peripheral arterial disease decreases muscle torque and functional walking capacity in elderly. Maturitas. 2015;81(4):480-6. http://dx.doi.org/10.1016/j.maturitas.2015.06.001. PMid:26119244. http://dx.doi.org/10.1016/j.maturitas.20...
Poland |
Cross-sectional case-control study |
n = 135 (83 M and 52 W), G1: 85 seniors with PAD and G2: 50 seniors without PAD, mean age: 70.35±7.7 years |
Exercise tolerance: 6WT, plus assessment of lower limb dynamic muscle strength and peak torque with an isokinetic dynamometer |
NA |
Lamberti et al.,1212 Lamberti N, Malagoni AM, Ficarra V, et al. Structured home-based exercise versus invasive treatment: a mission impossible? A pilot randomized study in elderly patients with intermittent claudication. Angiology. 2016;67(8):772-80. http://dx.doi.org/10.1177/0003319715618481. PMid:26635335. http://dx.doi.org/10.1177/00033197156184...
Italy |
Controlled RCT |
n = 27 (21 M and 6 W), mean age: 67±7 years |
Exercise tolerance and claudication: constant load treadmill test and 6WT. |
G1: home exercise, intermittent walking (1 min of exercise and 1 min of rest) 10 min per day, 6x per week, for 16 weeks. |
Quality of life: with SF-36 questionnaire. Also analyzed the cost/effectiveness of treatment and compliance. |
G2: open surgery or revascularization or both, plus instructed to remain active. |
Akerman et al.,1313 Akerman AP, Thomas KN, van Rij AM, Body ED, Alfadhel M, Cotter JD. Heat therapy vs. supervised exercise therapy for peripheral arterial disease: a 12-wk randomized, controlled trial. Am J Physiol Heart Circ Physiol. 2019;316(6):H1495. http://dx.doi.org/10.1152/ajpheart.00151.2019. PMid:31002283. http://dx.doi.org/10.1152/ajpheart.00151...
New Zealand |
Controlled RCT |
n = 22 (15 H and 7 W), mean of 75.3±8.9 years |
Exercise tolerance: walking test, 6WT. |
G1: heat therapy with immersions in a heated swimming pool (~39 °C) from 3 to 5x per week, plus resistance exercises and calisthenics wearing warm clothes, for 15 to 30 min. |
Internal temperature during physical activity: telemetry capsule. |
Oxygenation and volume of blood, vascular function: with FMD, NIRS, PWV, venous occlusion plethysmography, and CO re-breathing. |
G2: walking for 30 to 60 min, 2x per week. |
Both groups exercised for 12 weeks. |
Quality of life: with SF-36 questionnaire. |
|
Also analyzed compliance with program. |
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