In the present investigation, the authors have studied the distribution of lysotypes, fermentative types and tetrathionate- reductase in 110 strains of Salmonella typhi, isolated from hemocultures during the period 1966-1970, in the State of Guanabara, Brazil. In order to establish a better epidemiological configuration of the results, this study has been divided and effected in the six following regions: south, middle, north at the Central Railway, the Leopoldina Railway and the rural district. As a general outcome a predomination of the lysotypes A, E 1a, T and negative Vi strains has been obtained. It has stil been verified that 70,90% of the cultures were classified fermentative type Ii and that 95,42% of the strains were tetrathionate-reductase positives.