BRS 205, a soybean cultivar originated from the cross [BR-16(2) x Ocepar 8] x Tracy-M, is indicated for sowing in November in the State of Rio Grande do Sul, Brazil. Plants have determinate growth habit, white flowers, brown pubescence, low stature, and black hilum. It is resistant to soybean stem canker (Diaporthe phaseolorum f. sp. meridionalis), brown stem rot (Phialophora gregata), frogeye leafspot (Cercospora sojina), and bacterial pustule (Xanthomonas axonopodis pv. glycines). It is moderately resistant to powdery mildew (Microsphaera diffusa). In comparison with RS 7-Jacuí and BR-16, cultivar BRS 205 averaged 6% and 11% higher yields, respectively.