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Women Undergoing Chemotherapy and Their Cognitive Functions

Abstract:

Currently, cancer is a major scientific challenge. Chemotherapy has been the most promising alternative treatment to combat cancer. Along the way, cognitive changes can occur and therefore it is necessary to identify these changes, as they represent neurological complications with high improvement when treated. The objective of this study was to study executive functions in women with breast cancer undergoing chemotherapy, seeking to identify aspects such as cognitive flexibility, impulsivity / inhibitory control, operational memory, planning, decision making, categorization and fluency. This is a literature review of publications of the last five years in PubMed, Lilacs, Pepsico, SciELO and BVS. The following descriptors were used: avaliação neuropsicológica/ neuropsychological evaluation, funções executivas/functions executive, quimioterapia/chemotherapy and câncer de mama/breast cancer. 18 articles related to the topic were found. The studies showed the existence of changes in the executive functioning of women undergoing chemotherapy. It is noteworthy that these studies differed among themselves as regards the characterization of the sample and the methods used, which shows little standardization of neuropsychological assessment of this cognitive domain. It is concluded that the cognitive domains related to executive functions are most affected in women with breast cancer receiving chemotherapy. However, this information is still insufficient because subdomains of the executive functions need to be studied in greater integrity in order to achieve greater functional landscape. It is suggested that new studies on the screening of the executive functions must be performed.

Keywords:
Breast cancer; Chemotherapy; Executive functions

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